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Auburn at Purdue Prediction, Picks, Odds, and Line Movement for December 20, 2025

By: Kyle Kargel Published 12/20/2025, 06:34 AM ET

Auburn vs Purdue picks headline a high-profile neutral-site matchup in Indianapolis as these two programs collide in a contrasting-styles battle that immediately jumps off the board for college basketball picks and college basketball predictions. With Purdue installed as a clear favorite, the betting market is asking whether Auburn can hang around or if the Boilermakers impose their will early.

TLDR - Picks and Prediction

  • Spread Pick: Purdue -8.5
  • Total Pick: Under 154.5
  • Projected Final Score: Purdue 80, Auburn 70

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  • Purdue enters the game with a 10-1 record and has consistently controlled tempo this season.
  • Auburn is 8-3 but has shown defensive volatility against upper-tier opponents.
  • Purdue recently held Marquette to 59 points in a lopsided win.
  • The Boilermakers have leaned heavily on interior efficiency and rebounding advantages.
  • Auburn is operating with reduced frontcourt depth due to a season-ending injury.
  • Neutral-site games with contrasting SEC and Big Ten styles often hinge on pace control.

Odds and Line Movement

Current Odds

Team Spread Total
Auburn +8.5 154.5
Purdue -8.5 154.5

Line Movement - Spread

Date Time Auburn Purdue
12/19 10:20AM +8.5 (-110) -8.5 (-110)
12/19 11:42AM +8.5 (-102) -8.5 (-120)
12/19 11:43AM +9.5 (-110) -9.5 (-110)

Line Movement - Total

Date Time Over Under
12/19 10:20AM 152.5 (-105) 152.5 (-115)
12/19 11:27AM 153.5 (-105) 153.5 (-115)
12/19 11:27AM 154.5 (-110) 154.5 (-110)

Auburn vs Purdue Game Preview and Analysis

This neutral-site matchup sets up well for Purdue’s strengths. The Boilermakers have built their 10-1 start on efficiency, discipline, and an ability to dictate where and how opponents score. Their recent performance against Marquette highlighted that edge, as Purdue dominated the paint and limited second-chance looks.

Auburn comes in with an 8-3 record and enough athleticism to generate offense in spurts, but the Tigers have been less reliable defensively when facing structured half-court teams. That issue is magnified here, as Purdue thrives at slowing the game down and forcing opponents into contested shots late in the clock.

The frontcourt matchup is a major swing factor. Purdue’s interior presence has been a consistent advantage this season, while Auburn is now thinner up front and may struggle to hold its ground on the glass. If Purdue establishes that edge early, Auburn is likely forced into quicker possessions and lower-quality perimeter attempts.

From a totals perspective, the number has climbed into the mid-150s, but Purdue’s preference for controlled possessions and defensive rebounding suggests a game that tightens up as it goes along. If the Boilermakers get ahead, they are comfortable bleeding clock and limiting scoring opportunities.

Key Injuries and Notes for AUB and PUR

  • AUB: Center Emeka Opurum is out for the season due to a medical condition.
  • PUR: No injuries reported.

Final Score Prediction

Purdue 80, Auburn 70

ATS and Total Picks

  • Against the Spread: Purdue -8.5
  • Total: Under 154.5
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