Indiana Hoosiers vs Kentucky Wildcats Prediction and Picks - December 13, 2025
It's the Big 10 vs the SEC on Saturday evening, and we have an Indiana vs Kentucky prediction ready to rock and roll. The Hoosiers are off to a 113-72 destruction of Penn State to move to 8-2 on the year. Kentucky enters this contest off a 103-67 home win over North Carolina Central, and they are now at 6-4 on the year. These teams last met back in 2016, and the Hoosiers won that game by a score of 73-67. Continue reading to see our Indiana vs Kentucky prediction.
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Hoosiers Crush The Nittany Lions At Home
Indiana’s most recent game was a 113–72 win over Penn State on December 9, where Lamar Wilkerson exploded for 44 points, hitting 8-of-12 from three and 14-of-15 free throws. Tayton Conerway added 17 points and seven assists, and the Hoosiers shot 69% from the field overall. It was a statement performance after back-to-back losses to Louisville and Minnesota, and it showed how dangerous Indiana can be when their perimeter shooting is locked in.
Offensively, Indiana averages 88.2 points per game while shooting 50.3% from the field, one of the most efficient marks in the Big Ten. Wilkerson leads the team at 18.8 points per game, while DeVries adds 17.2 and provides consistent outside shooting. Tayton Conerway chips in 12.3 points and nearly 5 assists per game, giving the Hoosiers a steady backcourt presence. Reed Bailey and Sam Alexis provide size and rebounding inside, while freshman Trent Sisley has shown flashes of promise with 7.8 points per game. Indiana’s ability to spread the floor with multiple shooters makes them tough to guard, especially when Wilkerson is in rhythm.
Defensively, Indiana allows just 66.9 points per game and holds opponents to 39.2% shooting. They rebound well as a unit, pulling down 36 boards per game, and their ball movement on offense (20.4 assists per game) often translates into defensive energy. Conor Enright leads the team in assists and helps set the tone with his playmaking. The Hoosiers’ challenge against Kentucky will be slowing down the Wildcats’ balanced attack while maintaining their own offensive efficiency.
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Kentucky Hits Triple Digits Against NC Central
Kentucky’s most recent game was a 103–67 win over North Carolina Central on December 9, where Jasper Johnson had 22 points and Otega Oweh added 21. The Wildcats shot 61% from the field and dominated the boards 35-21, bouncing back from a tough 94–59 loss to Gonzaga just days earlier. It was a reminder of how dangerous Kentucky can be at home, where they’ve gone 6–1 this season.
Offensively, Kentucky averages 85.5 points per game while shooting 48.7% from the field. Oweh leads the team with 14.4 points per game, while Denzel Aberdeen adds 12.4 and Collin Chandler contributes 11.2. Freshman center Malachi Moreno has been a force inside, averaging 10.1 points and 7.1 rebounds, and Jasper Johnson provides scoring punch off the bench. The Wildcats share the ball well, averaging 19 assists per game, and their depth across positions allows them to attack in multiple ways.
Defensively, Kentucky allows 67 points per game and holds opponents to 39% shooting. They rebound at a high level (42 boards per game) and block 4.4 shots per contest, with Moreno and Brandon Garrison anchoring the paint. The Wildcats’ ability to control tempo and protect the rim has been key to their success at Rupp Arena. Against Indiana’s perimeter-heavy offense, Kentucky will need to close out on shooters while relying on their size advantage inside to dictate the flow of the game.
Indiana vs Kentucky Pick
Indiana vs Kentucky Spread Pick
- Kentucky -4.5 (5 Units)
Kentucky laying -4.5 feels like the right side given how well they’ve bounced back and the way they’ve controlled games at home. Their most recent outing was a 103–67 win over North Carolina Central on December 9, where Jasper Johnson had 22 points and Otega Oweh added 21 as the Wildcats shot 61% from the field and dominated the boards 35-221. That performance came just days after a tough loss to Gonzaga, and it showed how quickly Kentucky can reset and overwhelm opponents with their depth. Averaging 85.5 points per game while holding teams to just 67, the Wildcats have the balance to dictate tempo and wear down Indiana over 40 minutes.
Indiana, meanwhile, is coming off a 113–72 win over Penn State on December 9, highlighted by Lamar Wilkerson’s 44-point explosion. The Hoosiers average 88.2 points per game and shoot over 50% from the field, but they’ve also shown vulnerability against stronger defenses, dropping games to Louisville and Minnesota earlier this month. Kentucky’s size inside with Malachi Moreno and Brandon Garrison, combined with Oweh’s scoring and Denzel Aberdeen’s steady backcourt play, gives them the tools to slow Indiana’s perimeter attack. With the Wildcats’ ability to rebound, protect the rim, and share the ball, laying -4.5 looks justified — Kentucky has the defensive edge and home-court advantage to cover.
Indiana vs Kentucky Over/Under Pick
- Over 157.5 (4 Units)
The Over 157.5 looks like a strong angle in Indiana–Kentucky given how both teams are built to score and push tempo. Indiana’s most recent game was a 113–72 win over Penn State on December 9, where Lamar Wilkerson erupted for 44 points and the Hoosiers shot 60% from the field with 11 made threes. They average 88.2 points per game and move the ball well with over 20 assists per contest, making them one of the most efficient offenses in the Big Ten. Kentucky, meanwhile, is coming off a 103–67 win over North Carolina Central on December 9, where Otega Oweh scored 20 and the Wildcats shot 61% while dominating the glass. The Wildcats average 85.5 points per game and have multiple scoring options across their roster, with freshmen Malachi Moreno and Jasper Johnson adding depth to an already balanced attack. With both teams capable of hitting the 80s and neither defense likely to completely shut down the other’s strengths, the Over 157.5 feels well-positioned to cash.
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