San Francisco Dons vs Minnesota Golden Gophers Prediction and Picks - November 22, 2025

By: Dean Whitaker Published 11/22/2025, 07:10 AM ET
Cade Tyson looks to lead the Golden Gophers over the Dons
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Saturday evening on the college hardwood, and we have a San Francisco vs Minnesota prediction ready to rock and roll. The Dons enter this game at 4-1 on the year and off an 84-64 home win over Northwestern State. Minnesota is also 4-1 on the year, and they come in off a 66-54 home win over Chicago State. These teams last met back in 2023, and San Francisco won that game at home by a score of 76-58. Continue reading to see our San Francisco vs Minnesota prediction.

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Dons Crush Northwestern State

San Francisco sits at 4-1 after their most recent win, where balance and efficiency defined the box score. Mookie Cook led the way with 15 points on 5-of-6 shooting, including three triples, while Tyon Riley chipped in 11 points and five rebounds. David Fuchs provided a spark off the bench with 13 points, hitting 8-of-11 free throws, and L. Smiley added 12 points with three made threes. The Dons spread the scoring across the rotation, with nine different players contributing, and their ability to share the ball was evident in the 17 assists they recorded.

Offensively, San Francisco has been steady rather than explosive, averaging 81.4 points per game (159th nationally). Cook has been their most efficient scorer, while Riley and Beasley stretch defenses with perimeter shooting. The Dons also rebound well, pulling down 41 boards per game (top‑100 nationally), which allows them to extend possessions and create second‑chance opportunities. Their ball movement has been a strength, with 17 assists per game ranking them inside the top‑100, showing that this team thrives on unselfish play and spacing rather than relying on one star.

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Defensively, San Francisco has been impressive, allowing just 65.4 points per game, which puts them among the better mid‑major units nationally. They’ve held opponents under 37% shooting in multiple contests, and their length inside has made it difficult for teams to score in the paint. Gigiberia and Graham provide rim protection, while Riley and Smiley help contest shots on the perimeter. Against Minnesota, the Dons’ ability to combine rebounding with disciplined defense will be critical, as slowing down Cade Tyson and forcing the Gophers into half‑court sets is the best path to pulling off another win.

Defense Plays Well In Win Over Chicago State

Minnesota improved to 4-1 after a 66-54 win over Chicago State on November 18, a game where Cade Tyson once again led the way with 21 points. The Gophers built a 31-24 halftime lead and leaned on their defense to close things out, holding the Cougars to just 41% shooting and forcing 12 turnovers. Jaylen Crocker‑Johnson added 11 points and 11 rebounds, while Isaac Asuma chipped in 9 points and 7 assists. It wasn’t the prettiest offensive performance, but Minnesota’s ability to grind out wins with defense has been a hallmark of their early season.

Offensively, the Gophers average 76 points per game, with Tyson emerging as one of the Big Ten’s most reliable scorers at over 23 points per contest. Crocker‑Johnson provides a strong interior presence, averaging a double‑double, while Asuma has been steady as a playmaker, contributing more than 4 assists per game. The concern remains perimeter shooting, as Minnesota ranks near the bottom nationally at just 27% from three. That lack of spacing has forced them to rely heavily on Tyson’s shot‑making and Crocker‑Johnson’s rebounding to generate second‑chance opportunities.

Defensively, Minnesota has been excellent, allowing just 62.4 points per game, good for 20th nationally. They rebound well on the defensive end, ranking sixth in the country, and their ability to contest shots has kept opponents under 41% shooting. Tyson’s length helps on the perimeter, while Crocker‑Johnson anchors the paint. Against San Francisco, the Gophers’ challenge will be slowing down a Dons team that averages over 81 points per game and moves the ball well. If Minnesota can force the game into a half‑court battle and lean on their defensive discipline, they’ll have a strong chance to extend their winning streak.

San Francisco vs Minnesota Pick

San Francisco vs Minnesota Spread Pick

  • San Francisco -2 (4 Units)

San Francisco -2 looks like the right side given how well the Dons have balanced scoring and defense early in the season. They’re averaging 81.4 points per game while holding opponents to just 65.4, a profile that shows they can win both uptempo and grind-it-out contests. Mookie Cook has been efficient inside and out, while Tyon Riley and L. Smiley stretch defenses with perimeter shooting. Their rebounding edge at 41 boards per game also gives them extra possessions, which is critical against a Minnesota team that struggles from deep.

The matchup favors San Francisco because Minnesota leans heavily on Cade Tyson’s scoring and has shot just 27% from three-point range as a team. While the Gophers defend well, ranking top‑20 nationally in points allowed, their lack of consistent perimeter offense makes it difficult to keep pace with a Dons squad that moves the ball and gets contributions from multiple scorers. With San Francisco’s defensive discipline and rebounding advantage, laying the small number feels justified, especially in a game where their depth and efficiency should tilt the balance.

San Francisco vs Minnesota Over/Under Pick

  • Under 139.5 (5 Units)

The Under 139.5 lines up well because both teams bring defensive strengths that can slow the pace. San Francisco allows just 65.4 points per game, ranking among the better mid‑major defenses, while Minnesota sits top‑20 nationally at 62.4 points allowed per game. The Gophers’ struggles from three (just 27% shooting) further limit their ability to push the total upward, and San Francisco’s balanced but methodical offense averages 81.4 points per game, not the kind of tempo that typically drives overs against a disciplined Big Ten defense. With both sides leaning on rebounding and half‑court execution, this matchup profiles as a grind that favors the Under 139.5.

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