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St. John's Red Storm vs UConn Huskies Picks, Prediction, Odds, and Line Movement for Wednesday February 25 2026

By: Kyle Kargel Published 02/25/2026, 08:41 AM ET
St. John's vs UConn predictions

St. John’s vs UConn picks are front and center in this Big East showdown, and I’m breaking it down with a sharp betting lens. If you’re grinding through college basketball picks every night like I am, this is the type of matchup you circle. St. John’s sits alone in first place after taking the first meeting, and UConn is still searching for answers on defense.

TLDR - Picks and Prediction

  • Spread Pick: St. John’s +4.5
  • Total Pick: Under 146.5
  • Projected Final Score: St. John’s 74, UConn 72

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  • St. John’s won the first meeting 81-72 on February 6 at MSG.
  • The Red Storm shot 50% from the floor in that win.
  • Zuby Ejiofor posted 21 points and 10 rebounds in the first matchup.
  • St. John’s has won 13 straight games entering this contest.
  • Rick Pitino is 3-0 vs. Dan Hurley since arriving at St. John’s.
  • UConn dropped a home game to double-digit underdog Creighton after the first loss to St. John’s.
  • UConn’s defense has not been the same since Donovan Clingan left for the NBA.

Odds and Line Movement

Current Odds

Market St. John’s UConn
Spread +4.5 -4.5
Market Over Under
Total (146.5) 146.5 146.5

Line Movement - Spread

Date Time St. John’s UConn
02/24 07:05:20PM +4.5 (-102) -4.5 (-120)
02/24 07:04:46PM +5.5 (-115) -5.5 (-105)
02/24 11:25:35AM +4.5 (-106) -4.5 (-114)
02/24 10:53:04AM +4.0 (-106) -4.0 (-114)

Line Movement - Total

Date Time Over Under
02/25 03:44:48AM 146.5 (-115) 146.5 (-105)
02/25 01:40:47AM 146.5 (-110) 146.5 (-110)
02/24 11:25:35AM 145.5 (-115) 145.5 (-105)
02/24 10:53:04AM 145.5 (-115) 145.5 (-105)

St. John’s vs UConn Game Preview and Analysis

This almost feels like the 80s again. St. John’s is in first place, riding a 13-game win streak, and playing with real edge under Rick Pitino. The Red Storm already handled UConn once, winning 81-72 at MSG. They shot 50% in that game and controlled the paint.

Zuby Ejiofor was the difference. The 6-9 forward scored 21 points and grabbed 10 rebounds. He set the tone inside. Bryce Hopkins adds another 14 points per game, giving Pitino two strong frontcourt pieces that attack the rim and crash the glass.

On the other side, UConn’s defense has slipped. Dan Hurley has openly talked about it. Since Donovan Clingan left for the NBA, the Huskies do not have that same rim presence. In the first meeting, they struggled to protect the paint and allowed clean looks.

UConn also lost at home to double-digit underdog Creighton after falling to St. John’s. That tells me the issues are not a one-game problem. This time, the game moves to downtown Hartford at PeoplesBank Arena. That building holds more fans, but it is not the same tight home-court feel as Gampel Pavilion in Storrs.

From a betting angle, the spread opened around UConn -4 and was briefly pushed to -5.5 before settling back near -4.5. That tells me early money tested the Huskies, but buyback came in on St. John’s. The total opened at 145.5 and has ticked up to 146.5. I see value on the dog and lean under because this game should tighten up late.

St. John’s

St. John’s is playing with confidence. They attack inside and defend with energy. Ejiofor and Hopkins give them scoring in the paint, which is the exact area where UConn has shown cracks. Winning 13 straight is not a fluke. Pitino has them locked in on both ends.

UConn

UConn still has talent, but the defense is not championship level right now. Without Clingan, the rim protection is weaker. Hurley is searching for consistency. Moving this game to Hartford may help with crowd size, but it does not fix the interior matchup problem.

Key Injuries and Notes - SJU vs UCONN

  • UConn has struggled defensively since Donovan Clingan left for the NBA.
  • St. John’s has won 13 straight games entering this matchup.
  • Rick Pitino is 3-0 against Dan Hurley since taking over at St. John’s.
  • The game will be played at PeoplesBank Arena in downtown Hartford instead of Gampel Pavilion.

Final Score Prediction

I expect another tight, physical battle. St. John’s has the inside edge, and UConn is still trying to find its defensive identity.

  • Projected Final Score: St. John’s 74, UConn 72

ATS and Total Picks

  • ATS Pick: St. John’s +4.5
  • Total Pick: Under 146.5
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