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Virginia Cavaliers vs Louisville Cardinals Picks, Prediction, Odds, and Line Movement for Tuesday January 13 2026

By: Kyle Kargel Published 01/13/2026, 09:39 AM ET
Virginia vs Louisville picks and predictions

Virginia vs Louisville picks are worth a close look as these ACC programs meet with both teams trending toward low-scoring games but with situational factors pointing another way. This matchup stands out for bettors reviewing sharp college basketball picks, especially with Virginia surging under a new coach and Louisville leaning on pace and home court.

TLDR - Picks and Prediction

  • Spread Pick: Louisville -3
  • Total Pick: Over 155
  • Projected Final Score: Louisville 81, Virginia 76

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  • Virginia has won nine of its last ten games.
  • The Cavaliers have covered the spread in three straight games by an average of 10.5 points.
  • Five of Virginia’s last six games have stayed under the total.
  • Virginia has allowed just 65.7 points per game over its last six contests.
  • The under is also 5-1 in Louisville’s last six games.
  • Louisville is playing at a top-15 pace nationally, averaging 15.0 seconds per possession.

Odds and Line Movement

Current Odds

Team Spread
Virginia +3.5 (-106)
Louisville -3.5 (-114)

Line Movement - Spread

Date Time Virginia Louisville
01/12 02:48:37 PM +3.5 -110 -3.5 -110
01/12 07:23:24 PM +2.5 -102 -2.5 -120
01/12 08:04:51 PM +3.5 -110 -3.5 -110
01/13 07:34:10 AM +3.5 -115 -3.5 -105
01/13 09:10:55 AM +3.5 -106 -3.5 -114

Line Movement - Total

Date Time Over Under
01/12 02:48:38 PM 155 -110 155 -110
01/12 06:39:54 PM 153.5 -110 153.5 -110
01/13 08:20:30 AM 153.5 -115 153.5 -105
01/13 09:31:51 AM 154.5 -110 154.5 -110
01/13 09:32:08 AM 155.5 -110 155.5 -110

Virginia vs Louisville Game Preview and Analysis

Louisville swept both meetings last season by an average margin of 17 points, but this Virginia team looks very different under first-year head coach Ryan Odom. The Cavaliers have won nine of their last ten games, with their only loss coming in a triple-overtime thriller at Virginia Tech.

Defensively, Virginia has been strong, allowing just 65.7 points per game over its last six contests. That stretch includes the triple-overtime game, which makes the number even more impressive. The Cavaliers have also covered the spread in three straight games, suggesting the market has not fully caught up to their improvement.

Louisville, meanwhile, has cooled off a bit. The Cardinals are coming off a home win over Boston College but have failed to cover the spread in three straight games. Even so, Louisville continues to push tempo, ranking top-15 nationally in pace, which separates this matchup from many of Virginia’s recent grinder-style games.

Both teams are trending under, but personnel changes matter. Virginia is expected to get senior guard Jacari White back after missing five games. White is shooting 50 percent from three-point range this season, and his return should open up the floor for the Cavaliers. On the Louisville side, Ryan Conwell is expected back, while freshman Mikel Brown remains out.

With both offenses getting healthier and Louisville’s pace forcing extra possessions, this looks like a buy-low spot on the total.

Key Injuries and Notes (UVA / LOU)

  • UVA: Jacari White is expected to return after missing five games.
  • LOU: Ryan Conwell is expected to play.
  • LOU: Mikel Brown is expected to remain out.

Final Score Prediction

  • Final Score: Louisville 81, Virginia 76

ATS and Total Picks

  • Spread: Louisville -3
  • Total: Over 155
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