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Arizona Wildcats vs Arizona State Sun Devils Prediction and Picks - November 28, 2025

By: Dean Whitaker Published 11/27/2025, 03:25 AM ET
Jeff Sims looks to lead the Sun Devils over the Wildcats

Friday evening Big 12 College football action, and we have an Arizona vs Arizona State prediction locked and loaded for you. Arizona comes in off a 41-17 home win over Baylor to move to 8-3 on the year. Arizona State enters this game off a 42-17 road win over Colorado, and they are also 8-3 on the year. Arizona State won last year's meeting on the road by a score of 49-7. Can Arizona get revenge for that loss? Read on to see our Arizona vs Arizona State prediction.

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Cats Rip Apart Bears At Home

Arizona heads into the Territorial Cup at 8-3 overall and 5-3 in Big 12 play, riding high after a convincing 41-17 win over Baylor on November 22 in Tucson. Noah Fifita threw for 183 yards and a touchdown, while Ismail Mahdi added 93 rushing yards and a score. Kedrick Reescano was the star of the day, punching in three rushing touchdowns, and the defense sealed the victory with a late pick-six. That win marked Arizona’s fourth straight, a surge that has vaulted them back into the Top 25 and given them momentum heading into their rivalry clash with ASU.

The Wildcats’ offense has been efficient all season, averaging 407.6 yards per game and 33.5 points per contest, which ranks 29th nationally. Fifita has been the steady hand at quarterback, throwing for 2,677 yards and 25 touchdowns, while Mahdi leads the ground game with 732 rushing yards. Reescano has added 370 yards and eight scores, giving Arizona a strong one-two punch in the backfield. Kris Hutson and Jacob Cowing have provided reliable targets in the passing game, helping Arizona maintain balance. The Wildcats average nearly 22 first downs per game, showing their ability to sustain drives and wear down defenses.

Defensively, Arizona has been one of the better units in the Big 12, allowing just 309.5 yards per game and 20 points per contest, ranking 24th nationally. The secondary has been particularly strong, giving up only 159.7 passing yards per game, which places them among the top 10 in the country. The run defense has been more vulnerable at 149.8 yards per game, but the Wildcats have consistently come up with timely stops and turnovers. With bowl positioning and bragging rights on the line, Arizona’s defense will be tested by ASU’s rushing attack, but their recent form suggests they’re ready for the challenge.

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ASA Grabs Easy Road Win Against Colorado

Arizona State enters the Territorial Cup at 8-3 overall and 6-2 in Big 12 play, coming off a 42-17 win over Colorado on November 22 in Boulder. Raleek Brown was unstoppable, rushing for 255 yards and two touchdowns, including an electrifying 88-yard burst that sealed the game late. Jeff Sims added balance through the air with 206 passing yards and two touchdowns, while Derek Eusebio hauled in a long scoring grab. Despite committing four turnovers, the Sun Devils’ defense held firm, limiting Colorado to just 300 total yards. That victory kept ASU’s postseason hopes alive and set the stage for a high-stakes rivalry clash with Arizona.

The Sun Devils’ offense has leaned heavily on the ground game, averaging 197 rushing yards per contest and 416.9 total yards per game. Brown has been the centerpiece, rushing for 1,078 yards at 6.2 yards per carry, giving ASU a reliable workhorse who can control tempo and flip games with explosive runs. Sims has thrown for 772 yards and seven touchdowns, while also rushing for 423 yards, making him a dual-threat option when the passing game needs a spark. Ja’Kobi Tyson has been the top receiving weapon with 689 yards and eight touchdowns, while Metayer and Eusebio provide secondary options. Overall, ASU averages 26.3 points per game, ranking 79th nationally, and their ability to sustain drives shows in nearly 22 first downs per contest.

Defensively, ASU has been solid but not dominant, allowing 339.5 yards per game and 23 points per contest, ranking 54th nationally in scoring defense. The run defense has been respectable at 119.3 yards allowed per game, but the secondary has been more vulnerable, giving up 220.2 passing yards per contest. The Sun Devils have forced 13 turnovers this season, though ball security remains an issue with 14 giveaways of their own. Against Arizona, the defense will need to tighten coverage against Noah Fifita’s passing attack while relying on Brown to keep the offense on schedule. With both teams sitting at 8-3, bowl positioning and bragging rights are on the line, making this one of the most anticipated Territorial Cup matchups in recent memory.

Arizona vs Arizona State Pick

Arizona vs Arizona State Spread Pick

  • Arizona -1.5 (5 Units)

Backing Arizona at -1.5 feels justified given how consistent the Wildcats have been down the stretch. They’ve won four straight, including a convincing 41-17 victory over Baylor, and their offense has found balance behind Noah Fifita’s steady passing and the one-two punch of Ismail Mahdi and Kedrick Reescano in the backfield. Arizona averages 33.5 points per game and over 407 yards of offense, ranking inside the top 30 nationally in scoring. With Fifita throwing for 2,677 yards and 25 touchdowns, the Wildcats have the kind of quarterback play that travels well in rivalry games. Laying less than a field goal leans into their ability to finish drives and control tempo.

Defensively, Arizona has the edge that makes the spread appealing. The Wildcats allow just 20 points per game and 309 total yards, with a secondary that ranks among the nation’s best at only 159 passing yards allowed per contest. That strength matches up well against Arizona State’s passing game, forcing the Sun Devils to lean heavily on Raleek Brown. While Brown is dynamic, Arizona’s defense has shown it can limit explosive plays and force turnovers at key moments. In a rivalry game where emotions run high, Arizona’s balance on both sides of the ball and their recent form suggest they can cover the small number and walk away with bragging rights.

Arizona vs Arizona State Over/Under Pick

  • Over 48.5 (4 Units)

The Over 48.5 looks appealing because both offenses have shown they can consistently put points on the board. Arizona averages 33.5 points per game behind Noah Fifita’s 25 touchdown passes and a balanced rushing attack, while Arizona State leans on Raleek Brown’s explosiveness and Jeff Sims’ dual‑threat ability to generate chunk plays. The Sun Devils score 26.3 points per game, and their defense has been vulnerable at times, giving up 23 points per contest, which sets the stage for Arizona’s passing game to thrive. With both teams capable of hitting big plays and neither defense likely to completely shut down the other, this rivalry matchup has the ingredients to push past 48.5.

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