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Arizona Wildcats vs Cincinnati Bearcats Prediction and Picks - November 15, 2025

By: Dean Whitaker Published 11/13/2025, 06:00 PM ET
Brendan Sorsby looks to lead the Bearcats over the Wildcats

Big 12 college football action on Saturday afternoon, and we have an Arizona vs Cincinnati prediction locked and loaded for you. Arizona enters this contest off a hard-fought 24-20 home win over Kansas to move to 6-3 on the year. The Bearcats lost to Utah on the road two weeks ago by a score of 45-14, but they are still 7-2 on the year. Read on to see our Arizona vs Cincinnati prediction.

When it comes to college football selections, our College Football predictions are stellar.

Cats Gain Bowl Eligibility With Win Over Kansas

Arizona comes into this game at 6–3 overall and 3–3 in Big 12 play, fresh off a 24–20 win over Kansas that showed their resilience in tight contests. Quarterback Noah Fifita has been the steady hand guiding the offense, throwing for 2,200 yards with 23 touchdowns against just four interceptions. His ability to stay composed under pressure has been critical, especially in games where the Wildcats have had to grind out drives late. Running back Ismail Mahdi has added balance to the offense, rushing for nearly 600 yards on the season and giving Arizona a reliable option to keep defenses honest. Wideout Jayin Whatley has been Fifita’s favorite target, hauling in 35 catches for 420 yards and four scores, providing a consistent threat on the perimeter.

Defensively, Arizona has been one of the more underrated units in the country, ranking 17th nationally in total defense and seventh against the pass. They’ve allowed just 19.9 points per game, and their secondary has been particularly stingy, limiting explosive plays and forcing quarterbacks into mistakes. The Wildcats also boast a +8 turnover margin, which has been a difference-maker in close games. That ability to win the turnover battle has kept them competitive even when the offense stalls, and it will be crucial against a Cincinnati team that thrives on rhythm and tempo.

For Arizona, the key will be controlling possession and keeping Fifita upright against a Bearcats defense that likes to bring pressure. If Mahdi can establish the run and the defense continues to force turnovers, the Wildcats have a chance to pull off another road upset. This game is about proving they can hang with ranked opponents consistently, and the pieces are there for Arizona to make it a four-quarter fight.

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Bearcats Get Crushed By The Utes

Cincinnati enters at 7–2 overall and 5–1 in Big 12 play, sitting inside the top 25 despite a tough 45–14 loss to Utah earlier this month. Quarterback Brendan Sorsby has been the leader of the offense, throwing for more than 2,000 yards with 20 touchdowns and just two interceptions. His efficiency has kept the Bearcats moving, and when paired with running back Tawee Walker, who has rushed for over 530 yards, Cincinnati has been able to maintain balance between the air and ground attack. Wide receiver Cyrus Allen has been the big-play threat, averaging nearly 15 yards per catch and scoring nine touchdowns, giving Sorsby a reliable option to stretch defenses vertically.

The Bearcats’ offense has been productive, averaging 35.6 points per game and ranking among the top 25 nationally in rushing yards. Their ability to sustain drives and finish in the red zone has been a strength, though penalties have been an issue, as Cincinnati ranks near the bottom of the FBS in penalty yards per game. That lack of discipline has cost them momentum in key spots, and against a disciplined Arizona defense, it could be a deciding factor. Still, when Sorsby is in rhythm and Walker is finding lanes, this unit can put points on the board quickly.

Defensively, Cincinnati has been solid but not elite, allowing just under 22 points per game while ranking 46th nationally in scoring defense. They’ve been strong in the red zone, holding opponents to scores on just 77% of trips, but they’ve struggled at times against the pass, giving up over 225 yards per game. The Bearcats will need to tighten coverage against Fifita and Whatley, while relying on their front seven to disrupt Mahdi’s running lanes. With home-field advantage and a chance to stay in the Big 12 race, Cincinnati will be motivated to deliver a statement win. If they can clean up the penalties and keep their offense balanced, the Bearcats have the tools to protect their ranking and hold off a dangerous Arizona squad.

Arizona vs Cincinnati Pick

Arizona vs Cincinnati Spread Pick

  • Arizona +6.5 (2 Units)

Arizona +6.5 looks like a strong play given how resilient the Wildcats have been in tight games this season. Quarterback Noah Fifita has shown poise under pressure, spreading the ball effectively while limiting turnovers, and running back Ismail Mahdi has provided balance with his ability to move the chains on the ground. Arizona’s defense has been one of the most underrated units in the Big 12, ranking inside the top 20 nationally and forcing a steady stream of turnovers. That combination of efficient offense and opportunistic defense makes them well-suited to hang around against a ranked Cincinnati team, even on the road.

Cincinnati has been solid, but they’ve also shown vulnerability, particularly with penalties and lapses in pass coverage. Arizona’s ability to capitalize on mistakes and control tempo gives them a path to keep this game close into the fourth quarter. With Fifita’s accuracy, Mahdi’s consistency, and a defense that thrives on disrupting rhythm, the Wildcats have the tools to cover the number. Even if the Bearcats find ways to score, Arizona’s balance and toughness make +6.5 a valuable cushion in what projects to be a competitive matchup.

Arizona vs Cincinnati Over/Under Pick

  • Under 56 (3 Units)

The Under 56 feels like the right angle because both Arizona and Cincinnati have defenses that can dictate tempo and force offenses into long, methodical drives rather than quick strikes. Arizona has quietly built one of the more disciplined units in the Big 12, ranking inside the top 20 nationally in total defense and thriving on turnovers, which often stall opponents before they can build momentum. Cincinnati, meanwhile, has been especially tough in the red zone, holding opponents to scores on just over three‑quarters of their trips, and their front seven has consistently clogged running lanes to keep games from turning into shootouts. While both offenses are capable of putting points on the board, the combination of Arizona’s ability to limit explosive plays and Cincinnati’s knack for tightening up near the goal line suggests this matchup will be more of a grind. Add in the fact that penalties have slowed the Bearcats at times and Arizona prefers to lean on balance rather than all‑out tempo, and you get a game script that points toward a lower total where possessions are valuable and scoring opportunities are harder to come by.

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