Bowling Green Falcons vs. Louisville Cardinals Picks and Prediction for Saturday, September 20, 2025
We have an interesting non-conference game in Week 4 of the college football season as the Bowling Green Falcons will be heading to L&N Federal Credit Union Stadium in Louisville, Kentucky on Saturday afternoon to battle against the Louisville Cardinals in our Falcons vs. Cardinals prediction. The game is airing exclusively on the ACC Network, and this game is going to be intriguing as both teams have started the year off strong. The Falcons (2-1) are coming off a 23-13 home win against the Liberty Flames on Saturday. The Cardinals (2-0) are on a two-game winning streak to open the season as they are coming off Sept. 5’s 28-14 home win over the James Madison Dukes. Let’s take a closer look at the Georgia State Panthers vs. Texas State Bobcats prediction! College gridiron clarity — NCAAF picks for Bowling Green Falcons at Louisville Cardinals with key matchups.
Falcons Flying High
The Bowling Green Falcons are looking to open the year strong as they are 2-1 heading into this game, as they attempt to continue dominating before starting their conference schedule next week. Quarterback Drew Pyne has been playing well throughout the season as he has completed 57-of-85 (67.1%) of his passes for 529 yards with a pair of passing touchdowns to zero interceptions. The running game has running back Kaderris Roberts leading the way as he has recorded 27 rushing attempts for 152 yards (5.6 yards per carry) and also has been involved in the passing game with 10 catches for 55 yards (5.5 yards per reception). However, he is yet to find the end zone at all this year.
The defense of the Bowling Green Falcons has been a significant force for the program as they are tied for 47th in college football as they are allowing 18.0 points per game. Georgia State has done a good job as they are getting pressure on the opposing offense as they have tallied seven total sacks as well as forcing two interceptions and three fumble recoveries. The defense needs to work on getting into the backfield with more regularity.
Injury Report for Bowling Green
- Defensive lineman Ian van der Merwe: Undisclosed (Questionable)
- Running back Pasean Wimberley: Undisclosed (Questionable)
- Defensive lineman Martreece Dillard: Undisclosed (Questionable)
- Defensive lineman Brendon Rice: Undisclosed (Questionable)
- Wide receiver Austin Clay: Undisclosed (Questionable)
- Linebacker Andrew Hines III: Undisclosed (Questionable)
- Defensive lineman Isaiah Thomison: Undisclosed (Questionable)
- Linebacker Coleman Teasdale: Undisclosed (Questionable)
- Cornerback Gavin Harris: Undisclosed (Questionable)
- Defensive lineman Dayln White: Undisclosed (Questionable)
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Cardinals Flying High
The Louisville Cardinals need to extend their winning streak if they want to continue to be a threat at the beginning of the year. Quarterback Miller Moss is still looking to find his footing with the team as he has completed 30-of-48 (62.5%) of his passes for 374 yards with two passing touchdowns to two interceptions. However, the running game for the Cardinals has been strong behind running back Isaac Brown, posting 18 rushes for 230 yards (12.8 yards per attempt) with three rushing touchdowns while also being slightly involved in the passing game with three catches for 14 yards.
The defense for the Cardinals has been playing at an amazing level early on as they are giving up 15.5 points per game, which is tied for 37th in college football. Their defense has been able to apply pressure but not force turnovers as they have 10 sacks, one fumble recovery, and one interception.
Injury Report for Louisville
- Defensive lineman CJ May: Undisclosed (Questionable)
- Tight end Nate Kurisky: Undisclosed (Questionable)
- Linebacker Stanquan Clark: Ankle (OUT)
Bowling Green Falcons at Louisville Cardinals Pick
Spread Pick for Bowling Green Falcons at Louisville Cardinals
- Bowling Green Falcons +26.5 (5 units)
This is the first time these two programs are facing off against one another, so that makes it a bit more interesting. This feels like way too many points, as Miller Moss is still trying to find his footing in the offense while Drew Pyne continues to look solid. The lack of a threat for Louisville to get takeaways makes things more difficult, as Bowling Green does not need to score much to have the spread be covered. All in all, go with the Bowling Green Falcons getting 26.5 points on the road to cover the spread.
Over/Under Pick for Bowling Green Falcons at Louisville Cardinals
- Under 52.5 (4 units)
This game has the feeling of an under as the passing attack for both sides has been nonexistent compared to where they need to be in the passing game. The running backs have stepped up as a result, but the defenses should be equipped to sell out for the run. Neither team defensively is allowing too many chunk plays as the Falcons are 86th in college football with 5.5 yards allowed per play thus far, while the Cardinals' defense has been elite, placing them in second place with only 3.2 yards per play run against them. Take under 52.5 total points as these teams are not expected to be scoring too
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