Cincinnati vs. Oklahoma State Prediction and Picks for Saturday, October 18th, 2025
Use Code SSWC The Oklahoma State Cowboys (1-5, 0-3 B12) have dropped five consecutive games, and the odds are against them (+21.5) to snap their skid this weekend when they host the #24 Cincinnati Bearcats (5-1, 3-0 B12). We’ve got you covered with our Cincinnati vs. Oklahoma State prediction. Kickoff is scheduled for 8:00 ET from Boone Pickens Stadium in Stillwater, OK. Looking to win big this football season? We have the best College Football Picks to help you out!
#24 Bearcats Secure Fifth Straight Win
The Cincinnati Bearcats entered the year with high expectations, but Coach Scott Satterfield's group faded from media attention following a season-opening loss to Nebraska (20-17) in Week 1. After a couple of tune-up wins, Cincinnati is gaining momentum with a trio of Big 12 victories over Kansas (37-34), #14 Iowa State (38-30), and UCF (20-11), most recently. The Bearcats sit atop the Big 12 table at 3-0, and they’re priced at +900 to win the conference championship.
In terms of personnel, it’s QB Brenden Sorsby leading the offense this season. The signal caller has thrown for 1,448 yards on a 64.7% completion rate, adding 14 touchdowns and one interception. WRs Caleb Goodie (354 yards, 2 TD) and Cyrus Allen (294 yards, 5 TD) are Sorsby’s top targets out wide. RB Evan Pryor leads the ground game with 349 yards and two touchdowns on 44 carries (7.9 YPC).
- Cincinnati’s offense has been serviceable this season, ranking 50th in scoring (29.2 PPG), while putting up 418.6 yards per game (37th).
- On the defensive side, the Bearcats are 47th this season, allowing 23.0 points per game. In terms of yardage, they’re 115th, conceding 440.0 yards per contest.
Cowboys Slide to 1-5
It has been pure chaos for the Oklahoma State Cowboys football program this season. The management decided to fire Coach Mike Gundy following a 1-2 start, but things certainly haven’t gotten better since the 21-year vet was dismissed. The Cowboys now sit at 1-5 overall, which includes their 0-3 mark in Big 12 play. Okie State has now lost five straight games, getting blown out by #6 Oregon (69-3), dropping a home game to Tulsa (19-12) as 10.5-point favorites, and losing a trio of conference games to Baylor (45-27), Arizona (41-13), and Houston (39-17), most recently.
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Interim coach Doug Meacham has made a quarterback change, and it’s Sam Jackson V who will be under center for a second straight game. The QB has logged 161 passing yards on a 51.9% completion rate, posting a 1/1 TD/INT ratio. WR Gavin Freeman is the top target out wide, hauling in 19 passes for 203 yards and two touchdowns. Rodney Fields Jr. has spearheaded the rushing attack, picking up 257 yards on 55 carries (4.7 YPC).
- Offensively, the Cowboys are scoring 14.4 points per game (128th), while averaging 289.0 yards per week (126th).
- Defensively, they are 134th in the country this year, conceding 42.6 points per game. They’re allowing 526.0 yards per contest, which is 135th. For context, there are 136 D-1 FBS programs.
Cincinnati vs. Oklahoma State Pick
Spread Pick for Cincinnati vs. Oklahoma State
- Cincinnati Bearcats -21.5 (-110) (5 units)
I have absolutely no issues laying this type of number with Cincinnati on Saturday. This team is picking up steam, riding a five-game winning streak. They’ve posted an average margin of victory of +20.8 points during the five-game sample size. This +20.8 metric is skewed due to a 70-0 blowout over Northwestern State, but I think it’s a nice data point that proves the Bearcats aren’t afraid to run up the score on inferior opponents.
They’ll take on an Oklahoma State side that has dropped five straight games, giving up 42.6 points per game during the stretch! The Bearcats should destroy this team, and there’s a realistic chance that they win this game by 35+ points.
Over/Under Pick for Cincinnati vs. Oklahoma State
- Over 57.5 (-110) (5 units)
I was back-and-forth on this total, but I ultimately think it’s best to play the over. Cincinnati’s offense should do a bulk of the work in this one. The Bearcats are 4-1 to the over in their last five games.
The big question is whether or not Oklahoma State’s offense can contribute enough scoring. I think they can manage to score 17 points. Cincy’s defense is a middling group, and they’re actually allowing 440.0 yards per game. That’s 115th in the country! The Cowboys should be able to move the ball in this game, and all we really need is two to three successful possessions to get this game over. They’ve scored at least 13 points in three straight games. A 49-13 score would suffice, and I think that’s in the realm of possibilities.
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