Colorado vs. Kansas State Prediction and Picks for Saturday, November 29th, 2025

By: Trenton Pruitt Published 11/27/2025, 07:11 PM ET
Colorado vs. Kansas State Prediction
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It has been an underwhelming season for the Kansas State Wildcats (5-6, 4-4 B12), but they can still secure bowl game eligibility with a win over the lowly Colorado Buffaloes (3-8, 1-7 B12) on Saturday. We’ve got you covered with our Colorado vs. Kansas State prediction. Kickoff is scheduled for 12:00 ET from Bill Snyder Family Stadium in Manhattan, KS. Don’t get sacked this football season! Try our College Football Picks!

Buffaloes Drop Fourth Straight Game

This is the third season of the Deion Sanders era in Boulder, and this year’s Colorado Buffaloes team has not been very good. The Buffs enter the season finale at just 3-8. They’re 1-7 in Big 12 play, with the lone conference victory coming at home over #22 Iowa State (24-17) back on October 11th. They’ve since lost four games, with those defeats coming at the hands of Utah (53-7), Arizona (52-17), West Virginia (29-22), and #25 Arizona State (42-17), most recently. Colorado hasn’t been much better from a betting perspective, going just 3-7-1 ATS. Six of their 11 games have gone under the total.

In terms of personnel, freshman quarterback Julian Lewis has taken control of the offense. Lewis has thrown for 589 yards on a 55.3% completion rate, adding four touchdowns and no interceptions. RB Micah Welch has spearheaded the rushing attack, gaining 364 yards and two touchdowns on 86 carries (4.2 YPC). The wide receiver trio of Omarion Miller (687 yards, 8 TD), Joseph Williams (489 yards, 4 TD), and Sincere Brown (366 yards, 2 TD) has been the main targets in the passing attack. Williams is questionable with an undisclosed injury.

  • Offensively, the Buffaloes are scoring 21.5 points per game (102nd), while averaging 328.9 yards per week (104th).
  • Defensively, they are 104th in the country this year, conceding 31.1 points per game. They’re allowing 435.2 yards per contest, which is 121st.

Wildcats Lose a 51-47 Barnburner to the Utes

Meanwhile, the Kansas State Wildcats entered the year as one of the frontrunners to win this jumbled Big 12 conference. However, they fell flat on their faces with a 1-3 start. Coach Chris Klieman and his Cats have bounced back, winning four of their next seven games and improving to 5-6 overall. Bowl eligibility is still on the table for Kansas State. They had a chance to secure a six-win season last weekend on the road against #12 Utah, but squandered a 12-point lead with seven minutes left in a 51-47 loss. The Wildcats are now 5-6 ATS and they’ve gone 7-4 to the over.

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Like the team as a whole, QB Avery Johnson entered the year with high expectations as one of the Heisman favorites. The dual threat quarterback has been decent, throwing for 2,270 yards on a 59.9% completion rate, adding 18 touchdowns and six picks. Johnson has 441 yards and eight touchdowns on the ground, but RB Joe Jackson leads the charge with 769 rushing yards and five touchdowns. Top WR Jayce Brown (712 yards, 5 TD) is expected to miss the rest of the season, which means Jaron Tibbs (540 yards, 3 TD) will be Johnson’s main target in the passing game.

  • Kansas State’s offense has been mediocre this season, ranking 46th in scoring (29.1 PPG), while putting up 365.4 yards per game (81st).
  • On the defensive side, the Wildcats are 75th this season, allowing 27.1 points per game. In terms of yardage, they’re 78th, conceding 395.7 yards per contest.

Colorado vs. Kansas State Pick

Spread Pick for Colorado vs. Kansas State

  • Colorado Buffaloes +17.5 (-115) (5 units)

I’m not going to sit here and try to convince anybody that Colorado is good. However, we do have to draw the line somewhere and take a stand. I’m willing to take a shot on the Buffs at +17.5 on Saturday. For starters, Kansas State is just 5-6 both SU and ATS this year, and only one of their wins (@ Kansas 42-17) has come by 18+ points. Just to reiterate, the Wildcats have only stretched out a 3+ possession win in one of their last 11 games.

K-State is also without two of its best offensive playmakers for the remainder of the year. We’re all likely aware of the fact that RB Dylan Edwards (ankle) left the program. QB Avery Johnson’s top target, WR Jayce Brown (undisclosed injury), is also done for the season. And finally, on the flip side, Colorado’s freshman quarterback, Julian Lewis (4/0 TD/INT ratio) has yet to throw an interception this season. If the Buffaloes take care of the ball, which they have, ranking 65th in turnover margin per game (+0.0)–then they should manage to keep this game within three possessions.

Over/Under Pick for Colorado vs. Kansas State 

  • Over 50.5 (-108) (5 units)

Kansas State absolutely gashed #12 Utah on the ground last weekend, racking up 472 yards on 42 attempts (11.2 YPC). They’ll have a very favorable matchup to continue the ground game supremacy on Saturday, as they take on a Colorado squad that’s 134th in rushing yards allowed per game (224.0) and 132nd in rushing yards allowed per play (5.3). To put that in perspective, there are only 136 D1 programs.

On the flip side, Kansas State’s defense hasn’t given up much to write home about either. They’re allowing 27.1 points per game against FBS-level competition (75th). Overall, the Wildcats are ranked 99th in yards allowed per pass play (12.0) and 67th in yards allowed per rush (4.2). Colorado has scored 17+ points in 10 of their 11 games this season. They should be able to put up 20+ points against this underwhelming K-State defense. I’ll predict a 35-20 final in favor of the Wildcats.

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