Delaware vs Colorado Picks and Prediction for Saturday, September 6, 2025
The Delaware Blue Hens (1-0) are looking to build off their first win of the season as they are coming off a 35-17 home victory over the Delaware State Hornets last Thursday. Junior quarterback Nick Minicucci had a strong showing as he completed 28-of-36 passes for 251 yards with three passing touchdowns and zero interceptions while also running nine times for 44 yards (4.9 yards per carry) with a rushing touchdown.
The seventh-ranked Texas Longhorns (0-1) are looking to recover from their opening week loss against the Ohio State Buckeyes on the road 14-7 on Saturday. Senior quarterback Kaidon Salter struggled a bit as he completed 17-of-28 passes for 159 yards with a passing touchdown. He also ran the football 13 times for 43 yards (3.3 yards per carry) and added a rushing touchdown as well.
Your Saturday scout: NCAAF predictions for Delaware Blue Hens vs Colorado Buffaloes you can trust.
Blue Hens Looking to Attack
The Delaware Blue Hens wound up securing a win in the opening game of the season 35-17 at home against the Delaware State Hornets last week. The offense was able to move the football as they were 8-for-13 on third downs and a big reason was the team’s ability to move the ball on the ground, averaging 5.3 yards per rush.
The defense stepped up as they gave up 17 points on 349 total yards (149 passing, 200 rushing) in the game. The defense was able to force a pair of takeaways in the game, but also struggled as Delaware State ran for 4.9 yards per carry.
Delaware has been stepping up as they are tied for 48th in college football with 35.0 points per game. Their defense is stepping up early on as their 17.0 points per game allowed ranks tied for 69th in the nation.
Injury Report for Delaware
- Quarterback Zach Marker: Undisclosed (Questionable)
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Buffaloes Looking to Redemption
The Colorado Buffaloes are looking to recover from their last game as they lost at home against the Georgia Tech Yellow Jackets 27-20 last time out. The offense could not manage to get much going as the team was 5-for-13 on third downs and converted their singular fourth-down attempt.
The defense struggled a bit as they allowed Georgia Tech to score 27 points on 463 total yards of offense (143 passing, 320 rushing). The Yellow Jackets ran for 6.8 yards per carry, but the Buffs were able to force three takeaways on the day as well.
The Colorado Buffaloes have been a good offensive team as they are tied for 89th in the nation with 20.0 points per game. Their defense has been solid as they are giving up 27.0 points per game, which is tied for 102nd in college football.
Injury Report for Colorado
- Running back Dallan Hayden: Undisclosed (Doubtful)
- Wide receiver Omarion Miller; Undisclosed (Doubtful)
Delaware vs. Colorado Pick
Spread Pick for Delaware vs. Colorado
- Colorado Buffaloes -24.5 (4 units)
The Colorado offense looked lost at some points in the opening game, but Kaidon Salter proved he can perform well in his program debut. Nick Minicucci for the Blue Hens did not have a running game last week as he led the team in rushing yards as well. That lack of balance is going to cost them in this game. This game should not be close so take the Colorado Buffaloes laying all these points here.
| # | Handicapper | Profit |
|---|---|---|
| 1 |  Rob Vincilleti | +1,502.00 |
| 2 |  Pro Sports Picks | +1,421.00 |
| 3 |  Brick Haus Sports | +634.00 |
| 4 |  David Delano | +492.00 |
| 5 |  Michael Briggs | +355.00 |
Over/Under Pick for Delaware vs. Colorado
- OVER 52.5 (5 units)
These teams showcased their ability to score the football at a good level during Week 1 of the season. Both teams were able to move the football at a good level and the Buffs failed to record a sack in the opening game. Kaidon Salter and Nick Minicucci showcased their excellence as well so take OVER 52.5 POINTS to hit in this game.
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