Eastern Michigan Eagles vs. Buffalo Bulls Picks and Prediction for Saturday, October 4, 2025

The Eastern Michigan Eagles (1-4, 0-1 MAC) are struggling to begin the season as they are coming off a 24-13 road loss against the Central Michigan Chippewas on Saturday. Senior quarterback Noah Kim had a lesser game as he completed 17-of-28 passes for 175 yards with an interception as well as eight rushing attempts for 18 yards (2.3 yards per carry) and a rushing touchdown.

The Buffalo Bulls (2-3, 1-0 MAC) are struggling as they are on a two-game losing streak after Saturday’s 20-17 home loss to the UConn Huskies. Senior quarterback Ta’Quan Roberson was limited in the game as he completed 9-of-15 passes for 104 yards while also carrying the ball three times for seven yards (2.3 yards per rush).

Find the edge fast with NCAAF picks for Eastern Michigan Eagles vs. Buffalo Bulls.

Eagles Looking to Recover

The Eastern Michigan Eagles are coming off a 24-13 loss on the road against the Central Michigan Chippewas last week. Eastern Michigan was able to score 13 points on 298 total yards (175 passing, 123 rushing). The offense was able to run effectively as they averaged 4.2 yards per carry and a touchdown on 29 attempts. However, Eastern Michigan only had possession for 23:36 in the game. The loss was their fourth in five games this season and ninth of 10 going back to last season.

The defense had a respectable showing as they gave up 24 points on 451 total yards (140 passing, 311 rushing) in the game. The defense was able to hold the Chippewas to 4-of-13 on third downs, but allowed them to convert on all three fourth-down tries. Central Michigan was able to run for whatever they wanted, averaging 6.5 yards per carry throughout the four quarters.

Eastern Michigan’s offense has been limited as they are 91st in college football with 24.0 points per game. Their defense is abysmal to begin the season on as their 36.6 points per game allowed ranks 126th in the nation.

Injury Report for Eastern Michigan

• Wide receiver Elijah Holmes Holt: Undisclosed (Questionable)
• Running back James Jointer Jr: Undisclosed (Questionable)
• Defensive lineman Hector Gonzalez: Undisclosed (Questionable)
• Linebacker Zach Mowchan: Undisclosed (Questionable)
• Defensive lineman Jefferson Adam: Undisclosed (Questionable)
• Tight end Jackson Holt: Undisclosed (OUT)

Bulls Looking to Snap Their Losing Streak

The Buffalo Bulls are looking to recover from their last game as they lost at home against the UConn Huskies 20-17. The offense finished with 17 points on 329 total yards (125 passing, 204 rushing). The team was unable to pass the football as they averaged just 4.3 yards per attempt. Buffalo was also held to 4-for-15 on third downs.

The defense looked okay as they held UConn to 20 points on 320 total yards of offense (155 passing, 165 rushing). The team was not able to stop the run as the Huskies averaged 5.3 yards per carry in the game. UConn also did not turn the ball over.

The Eastern Michigan Eagles have been unable to score points consistently as they are 93rd in the nation with 24.0 points per game. Their defense has been clicking as they are giving up 19.6 points per game, which is 46th in college football.

Injury Report for Buffalo

• Quarterback Ta’Quan Roberson: Undisclosed (Probable)
• Cornerback Ramari Taylor: Undisclosed (Questionable)
• Running back Terrance Shelton Jr: Undisclosed (Questionable)
• Running back Messiah Burch: Undisclosed (Questionable)
• Wide receiver Bobby Mays: Undisclosed (Questionable)
• Wide receiver Dwayne Early Jr: Undisclosed (Questionable)
• Wide receiver Jasaiah Gathings: Undisclosed (Questionable)
• Wide receiver Chance Morrow: Undisclosed (Questionable)
• Tight end Ryan Daly: Undisclosed (OUT)

Eastern Michigan Eagles vs. Buffalo Bulls Pick

Spread Pick for Eastern vs. Buffalo Bulls

• Buffalo Bulls -10.5 (4 units)

Ta’Quan Roberson is entering the game with a hand injury, but is expected to play, so he should be able to go and step up in this matchup against a struggling Eastern Michigan program. Noah Kim has seen a drop in his production each of the previous three weeks, and the Bulls’ pass-defense is one of the more stout ones in college football this season. These programs have played every year since 2022 and Buffalo is 2-1 ATS in those games, so take the Buffalo Bulls to cover the spread at home.

Over/Under Pick for Eastern vs. Buffalo Bulls

• Over 54.5 (4 units)

These teams have been able to convert on third down throughout the season as Eastern Michigan is 28-of-69 (40.58%) so far while Buffalo is 26-of-72 (36.11%) to begin the year. Both teams are allowing the quarterback to look sharp as well when diving into the quarterback ratings as the Eagles rank 112th with a 119.4 opposing quarterback rating, while the Bulls are 49th with a 119.9 quarterback rating against. Take the over as the better bet to make in this game.