Georgia Southern vs Southern California (USC) Picks and Prediction for Saturday, September 6, 2025
Use Code SSWC Get ready for an incredible Week 2 showdown as the Georgia Southern Eagles battle it out with the USC Trojans in our Eagles vs. Trojans prediction. Set to unfold at the Los Angeles Memorial Coliseum on September 6th at 7:30 PM ET, this game, airing on FS1, promises an exciting matchup with two teams starting off differently. With these teams looking to step up in this matchup, let's dive into the stats, injuries, and key insights to preview what's in store.College gridiron clarity — NCAAF picks for Georgia Southern Eagles vs Southern California (USC) Trojans with key matchups.
Eagles Looking to Get Going
The Georgia Southern Eagles are getting ready to improve on the offensive side of the ball as they are coming off a 42-14 road loss to the Fresno State Bulldogs. Georgia Southern’s offense is led by quarterback JC French IV, who was able to complete 17-of-28 passes for 148 yards with two passing touchdowns and an interception in the opening game. Their total offense stands at 242.0 yards per game, with rushing accounting for a respectable 84.0 yards. The passing game has been one of the better in the country with an average of 158.0 yards per game
Defensively, Georgia Southern needs improvement as they are allowing 527.0 total yards per game, with their rush defense standing out, allowing 7.8 yards per carry. The Eagles have been unable to be a sufficiently defensive team and need to figure out ways to get stops.
Injury Report for Georgia Southern
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- No injuries to report
Trojans Dominant on the Field
The USC Trojans are looking to be a force this season after a strong ending to the 2024 season and are coming off a 73-13 home win over the Missouri State Bears. Quarterback Jayden Maiava stepped up in this game as he completed 15-of-18 passes for 295 yards with a pair of passing touchdown passes as well as two rushes for nine yards and a touchdown. As a team, they are ranked third nationally in passing yards, averaging 364.0 per game. USCs’ total offense, which averages 597.0 yards per game (second nationally) is clicking on all cylinders. The rushing game, contributing 233.0 yards per game (13th nationally), might see an increased emphasis to hand the ball off.
The Trojans’ defense, allowing an average of 224.0 total yards per game (15th nationally), has been their strength this season. Their rush defense, in particular, has been impressive, conceding only 65.0 yards per game (12th nationally). Their pass defense, allowing 159.0 yards per game (27th nationally), remains a strong point and will be crucial in containing Georgia Southern’s offense.
Injury Report for USC
- Cornerback Chasen Johnson: Undisclosed (Probable)
- Tight end Joey Olsen: Undisclosed (Questionable)
- Cornerback Alex Graham: Undisclosed (Questionable)
- Linebacker Anthony Beavers Jr: Undisclosed (Questionable)
- Cornerback Prophet Brown: Undisclosed (Questionable)
- Defensive lineman Jahkeem Stewart: Leg (Questionable)
- Kicker Caden Chittenden: Undisclosed (Questionable)
Georgia Southern vs. USC Pick
Spread Pick for Georgia Southern vs. USC
- USC Trojans -28.5 (4 units)
This one is pretty simple as the Georgia Southern Eagles did not show much offensively while the USC Trojans completely dominated. Coach Lincoln Riley may have his best roster since making the move from Oklahoma and that showed in Week 1. Jayden Maiava is one of the more underrated quarterbacks and in nonconference action, should continue to step up as he faces lesser competition. Even though it’s a large number, go with the Trojans to cover at home.
Over/Under Pick for Georgia Southern vs. USC
- Under 61.5 (4 units)
The Trojans' offense scored 73 points last week and easily covered the total themselves. However, they should be slowed down a bit this week as the Eagles can force turnovers and run the ball effectively. The Trojans' defense also bolstered up and was on full display in Week 1, allowing just 13 points in the blowout victory. Braylan Shelby was able to come off the edge last week for USC and record a pair of sacks. This defense applies pressure and should be able to keep the total low to hit under 61.5 total points.
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