Indiana vs Nebraska Picks and Prediction for Saturday October 10, 2026
The Indiana Hoosiers will head to Lincoln, Nebraska, Saturday for a Big Ten showdown against the Nebraska Cornhuskers. The game is scheduled to begin at 12 PM with national television coverage on FOX. Indiana enters the matchup ranked No. 7 in the country and will look to continue its impressive run against another conference opponent. The Hoosiers have established themselves as one of the top teams in college football and will face another challenge on the road. Nebraska will welcome Indiana to Memorial Stadium, looking to take advantage of its home crowd and pick up a significant conference victory. The Cornhuskers have an opportunity to make a statement against a nationally ranked opponent. Indiana is favored by 7.5 points, with the total sitting around 48.5 points. The Hoosiers are -305 on the money line, while Nebraska is +250. Stay in the action with our College Football Picks.
Hoosiers look to stay perfect
Josh Hoover leads the Indiana offense this season with 1,101 passing yards and 15 touchdowns on 76 completions. Turbo Richard leads the Hoosiers rushing attack with 587 yards and five touchdowns on 63 carries. Lee Beebe Jr. has added 520 yards and four touchdowns on 89 carries, while Jayreon Campbell has chipped in 50 yards on eight carries. Charlie Becker leads all Indiana receivers with 477 yards and eight touchdowns on 27 catches. Nick Marsh has added 341 yards and four touchdowns on 23 receptions, while Shazz Preston has contributed 123 yards and one score on nine catches.
Indiana Hoosiers rolled offensively a week ago, compiling 593 yards to score 47 points in the win. Defensively, Indiana was just as stout, giving up 15 points on 254 yards in the game. Josh Hoover led the charge for the Indiana offense a week ago, completing 20 passes for 251 yards and four scores in the game. Richard was the top ball carrier on the team with 204 yards and one touchdown on 13 carries. Lee Beebe Jr. added 122 yards and one touchdown on 18 carries. Nick Marsh was the top receiver on the team with 120 yards and one touchdown on 7 receptions, and Charlie Becker chipped in eight catches for 107 yards and two scores.
Nebraska goes for the huge upset
Anthony Colandrea leads the Nebraska offense this season with 1,142 passing yards and 13 touchdowns on 94 completions, along with 249 rushing yards and two touchdowns on 38 carries. Jamal Rule leads the Cornhuskers rushing attack with 333 yards and five touchdowns on 42 carries. Mekhi Nelson has added 266 yards and four touchdowns on 56 carries. Kwazi Gilmer leads all Nebraska receivers with 387 yards and six touchdowns on 29 catches. Jacory Barney Jr. has added 233 yards and two touchdowns on 18 receptions, while Luke Lindenmeyer has chipped in 116 yards and one score on 12 catches.
The Nebraska offense dominated last week, scoring 48 points, including twenty in the fourth quarter on 447 total yards. Defensively, Nebraska was the better team, giving up 23 points on 395 yards and forcing 2 turnovers in the win. Anthony Colandrea led the way for Nebraska last week, completing 26 passes for 238 yards and three scores, and ran the ball 10 times for 108 yards. Isaiah Mozee added 46 yards on 8 carries, and Mekhi Nelson chipped in 39 yards and two scores on 14 carries. Kwazi Gilmer led the way for the Nebraska receivers with 147 yards and two touchdowns on 11 receptions.
Indiana vs Nebraska Picks and Prediction
Pick: Indiana Hoosiers -7.5
Indiana has continued to prove itself as one of the best teams in the country and should have another opportunity to show its strength against Nebraska. The Cornhuskers will have a tremendous home-field advantage and should come out with plenty of energy against a highly ranked opponent. Indiana will need to handle the early pressure and avoid giving Nebraska extra possessions. The Hoosiers have the offensive ability to put together consistent scoring drives and should be able to challenge the Nebraska defense throughout the afternoon. Nebraska could keep things competitive early, but Indiana has the talent and overall balance to take control in the second half and leave Lincoln with another victory.
Pick: Under 48.5
Nebraska will need to find a way to slow down Indiana if the Cornhuskers want to stay competitive Saturday afternoon. The Hoosiers have plenty of offensive weapons, but playing on the road against a motivated conference opponent could create some difficult situations. Nebraska should try to establish its running game and control the tempo to keep Indiana's offense off the field. The Hoosiers will have opportunities to score, but their defense should also be capable of making things difficult for the Cornhuskers. Neither team should want to get into a game filled with turnovers and short fields. Look for a physical Big Ten matchup with enough defensive stops to keep the combined score under the total.