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Louisiana Ragin' Cajuns vs. Eastern Michigan Eagles Picks and Prediction for Saturday, September 20, 2025

By: Patty Reyes Published 09/18/2025, 05:27 PM ET
Louisiana Ragin' Cajuns at Eastern Michigan Eagles Picks and Prediction for Saturday, September 20, 2025

The Louisiana Ragin Cajuns (1-2, 1-2 O/U) are facing off against the Eastern Michigan Eagles (0-3, 1-2 O/U) are battling it out in Week 4 of the 2025 college football season on Saturday afternoon inside Rynearson Stadium in nonconference action for our Ragin Cajuns vs. Eagles prediction. The Ragin' Cajuns are coming off a 52-10 road loss on Saturday against the Missouri Tigers. The Eagles have opened the season on a three-game losing streak as they are coming off their 48-23 road loss against the Kentucky Wildcats on Saturday. Before kickoff: NCAAF predictions for the Louisiana Ragin' Cajuns at Eastern Michigan Eagles in one clean snapshot.

Ragin' Cajuns Looking to Find Momentum

The Louisiana Ragin' Cajuns have been trying to flip the switch as they are 1-2 after their 52-10 road loss against the Missouri Tigers. The offense as a whole has been quiet as they are ranked 131st in yards per game. Quarterback Daniel Beale has struggled under center this season as he completed 15-of-36 (41.7%) of his passes for 91 yards with one touchdown pass. Running back Zylan Perry has been doing some lifting for the offense as well as he has 30 rushes for 226 yards (7.5 yards per attempt) with a rushing touchdown while also adding a pair of receptions for 14 yards (7.0 yards per catch).

Louisiana’s defense was able to perform at a decent level as they are giving up just 25.3 points per game. The defense needs to figure out how to apply more pressure, as they have five sacks, two interceptions, zero forced fumbles, and one fumble recovery. They need to figure out how to put things together if they want to be more successful.

Injury Report for Louisiana

  • Quarterback Walker Howard: Oblique (OUT)

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Eagles Have Their Wings Clipped

The Eastern Michigan Eagles are looking to recover after losing last week to the Kentucky Wildcats on the road 48-23. The offense is struggling as they are averaging 24.3 points per game up to this point. Quarterback Noah Kim has not done too much passing the football as he completed 66-of-105 (62.9%) of his passes for 767 yards with four passing touchdowns and an interception. He also ran the ball at a decent level with 20 rushes for 43 yards (2.2 yards per carry) with one rushing touchdown. The team needs to figure out how to continue getting the ball to wide receiver Terry Lockett Jr as he has been their deep threat with 16 catches for 230 yards (14.4 yards per reception) with one touchdown reception.

The defense has been abysmal as they are giving up 42.7 points per game so far this season. The defense recorded just one sack, zero interceptions, one forced fumbles, and zero fumble recoveries. If the team can wake up defensively, they can start to correct their woes.

Injury Report for Eastern Michigan

No injuries to report

Louisiana Ragin' Cajuns vs. Eastern Michigan Eagles Pick

Spread Pick for Louisiana vs. Eastern Michigan

  • Louisiana Ragin' Cajuns -140 (5 units)

There is a significant difference between these two teams and it is clear. The Eagles are struggling offensively and are one of the worst defenses in college football. They are three games in and have recorded one sack and have zero takeaways, which means the Ragin Cajuns can simply not worry about shaky pass protection and Daniel Beale will have a clean pocket for a majority of the game. All in all, go with the Louisiana Ragin' Cajuns to win on the road.

Over/Under Pick for Louisiana vs. Eastern Michigan

  • Over 49.5 (5 units)

Similar thought process as the moneyline pick, when we have a defense that is not getting stops or forcing turnovers, where do the points go? They have allowed at least 48 points in two of their three games and they still allowed 28 to Long Island University. Louisiana may not be much of an offensive threat, but with the Eastern Michigan defense, who isn’t? Take over 49.5 total points as both teams should be able to score at a relatively good level throughout the game.

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