Missouri State vs Delaware Picks and Prediction for Tuesday October 20 2026

By: Eddie Kline Published 10/18/2026, 10:56 PM ET

Conference USA foes will square off on Tuesday night, when the Missouri State Bears take on the Delaware Blue Hens from Delaware Stadium. The opening kickoff will take place at 7:00 pm EST on Tuesday October 20, 2026. The Blue Hens opened as a three-point favorite and the total is 51.5. The game will be televised on ESPNU. Be sure to check out our free college football picks for more NCAAF predictions throughout the season.

Missouri State needs to improve on defense

The Missouri State Bears won seven games in their first season of FBS football and finished with a 5-3 record in the Conference USA. The Bears (2-4) started the 2026 campaign with a 50-0 loss at Texas A&M and were competitive in a ten-point loss at SMU. On Wednesday, Yousef Obeid kicked a 20-yard field goal as time expired to lift Missouri State to a 24-21 home victory versus Kennesaw State.Β 

Duke transfer Henry Belin IV got the start for Missouri State at quarterback and provided experience at the position. Belin IV shredded the Kennesaw State secondary for 300 yards and two touchdowns. Isaiah Myers caught seven passes for 135 yards and scored twice for the Bears.Β 

Missouri State struggles on both sides of the ball. The Bears rank fourth worst in Conference USA in total offense (357 ypg) and are scoring a shade above 22 points per game. Missouri State owns the worst defense in the conference and surrenders 30.5 points on average.

Delaware moving it through the air

The Delaware Blue Hens were one of the most consistent FCS programs before becoming a member of Conference USA. The Blue Hens (2-4) split their four non-conference games and are looking for their first conference victory this season. On Tuesday, Delaware was penalized 13 times for 101 yards during a disappointing 33-30 road loss against Middle Tennessee.Β 

Delaware freshman QB Tyler Bell shined in his first collegiate start with 306 passing yards and two touchdowns. Senior WR Donovan Lewis caught six passes for 83 yards. The Blue Hens were limited to a dismal 70 rushing yards on 30 carries.Β 

The Blue Hens lead the conference in passing offense (271 ypg) and are scoring 22.8 points per game. Jo Silver leads the team with 230 rushing yards on 58 carries. Delaware ranks near the bottom of the conference in total defense and is giving up 26.8 points per contest.

Missouri State vs Delaware Picks and Prediction

Pick: Delaware -3

This will be the first meeting at the FBS level for these two programs. In Missouri State’s lone conference game on the road they lost to Western Kentucky by a 34-13 final score. Delaware senior QB Nick Minnicucci has missed the last two games with a lower leg injury, but Tyler Bell showed plenty of potential. Take the Blue Hens to win and cover at home.

Pick: Over 51.5

In three road games this season, Missorui State has surrendered 118 points. The Bears have the worst passing defense in the conference and the Blue Hens are lethal through the air. Delaware just scored 30 points in a losing effort and will exceed that number at home. Take the over.Β 

Final Score Prediction: Delaware 34, Missouri State 24

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