New Mexico State Aggies vs. New Mexico Lobos Picks and Predictions- Saturday, September 27th

By: Anthony Leute Published 09/25/2025, 04:20 PM ET
New Mexico State versus New Mexico Prediction
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New Mexico State Versus New Mexico Picks and Predictions - Saturday, September 27th

New Mexico State is traveling to University Stadium in Albuquerque, New Mexico for their week five matchup against New Mexico; keep reading for our New Mexico State versus New Mexico prediction. New Mexico State is ninth in the C-USA with a season record of 2-1 and a conference record of 0-1. New Mexico is fifth in the MWC with a season record of 2-1. New Mexico came out on top last season in their game against New Mexico State with a final score of 50-40. Kickoff is scheduled for 4:00 p.m. EDT. Donโ€™t get penalized! Increase your bankroll with our NCAAF Betting Picks!

New Mexico State Relying On Defense

New Mexico State is coming off a loss last week to Louisiana Tech with a final score of 30-20. This would be the first loss of the season for the Aggies as they look to find their first road win of the season on Saturday.

The defense for the Aggies this season has looked great as they rank 42nd overall in points and 55th in total yards allowed. The Aggiesโ€™ defense has excelled in stopping the pass game of their opponents, as they rank 36th in the country in passing yards and 75th in passing yards per reception at 6.9. New Mexico State has shown elite defense as they have four interceptions so far this season in their three games played.

On offense, the Aggies have struggled, ranking 130th in points and 133rd in total yards. The worst part of New Mexico Stateโ€™s offense has been their run game which sits 136th in rushing yards and rushing yards per carry at 1.9. Graduate Running Back Kadarius Calloway leads the team in rushing yards with only 58 yards in his three games played.

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Injuries:

  • T. King WR Questionable - Undisclosed
  • A. Williams III WR Questionable - Undisclosed

New Mexicoโ€™s Stalwart Defending

New Mexico picked up another win last week versus UCLA with a final score of 35-10. This is the second win of the season for the Lobos and their first win on the road. New Mexico has yet to face a conference opponent this season.

The Lobosโ€™ defense has been one of the better defenses in the country. New Mexico ranks 42nd in points and 46th in total yards allowed. The more impressive part of the Lobosโ€™ defense has been their run defense with New Mexico ranking 50th in rushing yards allowed. The defense has done a great job at forcing their opposition back during the run and turning the opponent's run game into negative yards. In their three games played this season, five of their defenders have tackles for a loss, which has helped their team keep the opposing run game in check.

On offense, the Lobos are not too impressive, running 104th in points and 121st in total yards. New Mexico has relied more on its run game to generate yards as it sits 77th in rushing yards and 46th in rushing yards per carry at 4.9. The Lobos' pass game has not looked great, with New Mexico sitting 126th in passing yards and 115th in passing yards per reception at 6.1. Junior Quarterback Jack Layne this season has a pass completion percentage of 66.7% and has 515 total passing yards in his three games started this season.

Injuries:

  • No injuries to report.

New Mexico State Versus New Mexico Picks and Predictions

Spread Pick for New Mexico State Versus New Mexico

  • New Mexico -13.5 (-115) (4 units)ย 

New Mexico had a record against the spread last season of 4-1-0 against non-conference teams. New Mexico State had a record of 1-3-0 against the spread against non-conference teams last season. While New Mexico State does thrive at stopping the pass game, they do not excel as well at stopping the run game. New Mexico should have little issue generating points against the Aggies while also preventing them from scoring. This is going to lead to a one-sided game, which should see the Lobos covering their spread.

Over/Under Pick for New Mexico State Versus New Mexico

  • Over 53.5 (-110) ( 4 units)ย 

New Mexico State had an over/under record of 4-2-0 as a road underdog last season. New Mexico had an over/under record of 2-0-0 last season as a home favorite. While we have two strong defensive teams, we should see a competitive game between these two teams and I believe this line is too low for even this game. New Mexico, since 2023, has an over/under record of 9-3-0 at home.

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