Oklahoma Sooners vs. Alabama Crimson Tide, Prediction, Picks, Odds and Preview, Saturday, November 15, 2025
Use Code SSWC Two top-ranked SEC teams go at it on Saturday and we’re making sure you have the play of the day with our Oklahoma vs. Alabama predictions. The No. 11 Sooners (7-2 SU, 4-4-1 ATS) are coming off of a bye week, but in their most recent action they took down No. 14 Tennessee on the road, 33-27, as +2.5 underdogs. The 4th-ranked Crimson Tide (8-1 SU, 6-2 ATS) got past LSU at home last Saturday, 20-9, as -10 favorites. Kickoff from Bryant-Denny Stadium is scheduled for 3:30 EST. If you are struggling to pick winners, you've come to the right place. We have the strongest College Football Picks.
Oklahoma needs a resume boost
This will be the third straight ranked conference opponent for the Sooners who have split their last two games. The team scored 33 points in their most recent effort, their top offense effort over a month’s worth of games.
Oklahoma, the 11th-ranked team in the land, is 2-2 SU over their last two games, with their offense averaging 22.8 points per game. On the year, they average 28.9 points a game and 373.7 total yards, both 11th in the SEC. Their passing attack also ranks 11th in the conference, with 236.7 yards per game. John Mateer threw for 159 yards and ran for 80 in the win over Tennessee. The senior QB has thrown 1,949 yards, with 8 TDs and 7 INTs this season. Isaiah Satenga III is fifth in the SEC with 692 receiving yards. The Sooners’ run game produces 137 yards per game, led by Tory Blaylock with 401 yards and 4 TDs on 94 carries.
The Sooners’ defense matched the offense over the past four games, allowing 22.8 points per game, while on the year, they’ve allowed 14.1 points, the best mark in the SEC. Their total defense also tops the conference, allowing 264.2 yards per game. They have the second-best run D, allowing 82.4 yards and fourth-best passing D in the conference, with 181.8 yards per game going against them. Oklahoma has recorded 33 sacks and 5 interceptions. After a sack and fumble recovery versus Tennessee, R Mason Thomas is tied for fifth in the SEC with 6.5 sacks. Kip Lewis leads Oklahoma with 53 tackles.
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Thomas (leg) was injured against Tennessee and may not play in this one. LB Kobe McKenzie (undisclosed) is also questionable.
Team notes
- Thomas was announced as one of 17 semifinalists for the Chuck Bednarik Award for the Outstanding Defensive Player of the Year.
- Tate Sandell is 18-19 on field goal attempts and 6-6 on attempts of 50+ yards, with a long of 55 yards.
- Team is tied for fifth in the country with 131 first downs allowed.
- The Sooners have allowed a combined 20 points in the first quarter.
Alabama riding high
The wave keeps on cresting for the Crimson Tide, winners of eight straight games and one of only two undefeated teams in SEC play. They had their best defensive effort in conference play last weekend, with the 9 points allowed the second fewest in a game this season.
Scoring has been down for the Tide over their last four games, with the team averaging 28.3 points per game in that stretch. Their scoring offense ranks eighth in the SEC, averaging 32.8 points per game. In the yardage department, Bama is gaining 403.1 yards each week, also eighth in the conference. They have the third-best passing attack with 291.2 yards each game. Ty Simpson threw for 277 yards versus LSU, his third straight game with over 250 passing yards and no interceptions. The junior QB is second in the SEC with 2,461 yards with 21 TDs and only 1 interception. On the ground, Alabama is averaging 111.9 yards each week. Jam Miller has a team-best 321 yards on 88 carries.
Fourth-ranked Alabama possesses the third-best scoring defense in the SEC, allowing 17.2 points per game. The 303.2 total yards per game yielded by the team is also the third-best mark in the conference. They have the second-best passing defense, allowing 164.1 yards per game, aided by 8 interceptions and 18 sacks. Against the run, the Tide are allowing 139.2 yards per game. Justin Jefferson leads the team with 54 tackles, adding two sacks, an interception and two pass deflections. Yhonzae Pierre leads the team and is seventh in the conference with 6 sacks.
Team notes
- Simson was named one of 13 semifinalists for the Maxwell Award for the most outstanding player in college football.
- Lotzeir Brooks is 15th in the SEC, averaging 16.1 yards per reception.
- Tied for 24th in the nation with just 47 penalties on the year.
- The team ranks 13th overall in first downs defense, allowing their opponents just 148 first downs through nine games.
Oklahoma vs. Alabama Picks
Spread Pick for Oklahoma vs. Alabama
- Oklahoma +6 (4 units)
These two storied programs have met only seven times through the years. Oklahoma owns a 4-2-1 SU advantage in the head-to-head series, including a 21-point win in their first meeting as conference rivals last season. Oklahoma is 3-0 SU and ATS on the road this season and had a week to line this one up. The Sooners’ best option would be to attack Alabama on the ground, but they don’t have a sound enough attack to do enough damage on that front. They do have a strong enough passing attack to move forward and get into scoring position, though that is easier said than done versus Bama, who is 5-0 SU and ATS at home this season. The good thing for the visitors is that their passing defense can match the Tide’s efforts and slow that offense down. Bama will likely not be able to establish any running game either. Oklahoma is 2-1 SU and 3-0 ATS in the last three meetings between the teams.
Take the Sooners, getting the points.
Over/Under Pick for Oklahoma vs. Alabama
- Under 46 (5 units)
This matchup features two of the top three defenses in the SEC. In last season’s meeting, the teams combined for 27 points. With just three games to play, things are getting tight and teams are getting more bruised and battered on top of it. The Sooners’ offense has been down in the scoring department, and they’ve scored 26 points or less in three of their last four games, including a six-point effort against Texas, the second-best defense in the conference, at home. Alabama’s offense has also been scoring less of late and is coming off of their lowest offense output since the season opener. The under is 2-1 in the last three games between these two teams and 12-6 between the teams this season.
Take the under.
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