Old Dominion (ODU) vs. Marshall Picks and Prediction, Saturday, October 11, 2025

By: Jason Green Published 10/09/2025, 05:55 PM ET
Old Dominion vs. Marshall prediction
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In a Sun Belt affair on Saturday afternoon at Joan C. Edwards Stadium in Huntington, West Virginia, Marshall (2-3) plays host to Old Dominion (4-1). Since losing to a ranked Indiana team in their season opener, Old Dominion has run the table with four straight wins, while Marshall is coming off a barnburner loss. Here in this Old Dominion vs. Marshall Prediction, check out the full score info and other free NCAAF picks.

ODU is a big betting favorite in this game, posted at -14.5 with the total sitting at 57.

ODU is Killing it on Defense

ODU is tied for 16th in the nation, only giving up an average of 14.6 ppg overall, and in their last two games, they have only given up seven points in each. In their last game, they were at home in a 47-7 beatdown over Coastal Carolina, where they outgained them 619 yards to 189 yards and rushed for 302 yards. Colton Joseph passed for 315 yards with four TD and no INT, Trequan Jones rushed for 98 yards, and Na'eem Abdul-Rahim Gladding led the way with 101 receiving yards. The Monarchs covered as a 20-point favorite and are 4-1 ATS on the season.

  • ODU has one of the best run games in the nation, ranking seventh in rushing yards per game and 57th in passing yards per game.
  • Joseph (1,215 yards 12 TD 4 INT) had three picks and no TD in the opener but has 12 TD and only one INT in the last four games.
  • Jones (451 yards 4 TD) is the lead back and the second leading rusher is Joseph (433 yards 5 TD) and each is averaging over eight yards per carry.
  • Three Monarchs have at least 295 receiving yards, led by Ja'Cory Thomas (343 yards 3 TD).
  • ODU will be facing a Marshall defense that only ranks 123rd against the pass and 84th against the run.

Marshall Puts Up 51 Points and Still Loses

In their last game, Marshall was on the road and while their offense blew up for 51 points, they lost to Louisiana 54-51 in overtime. They took the loss despite outgaining the Rajin’ Cajuns 503 yards to 461 yards and forcing two turnovers while only committing one. Carlos Del Rio-Wilson passed for 258 yards with three TD and no INT, Michael Allen rushed for 138 yards and two TD, and Demarcus Lacey had 146 receiving yards and two TD. The Thundering Herd failed to cover as a 2-point favorite and they had covered the spread in their previous two games.

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  • Like Old Dominion, Marshall is led by the run game, ranking 39th in rushing yards per game and only 119th in passing yards per game.
  • Del Rio-Wilson (637 yards 9 TD 0 INT) has been airing it out more in the last two games, where he had at least 258 yards and seven TD.
  • Allen (273 yards 3 TD) leads the team in rushing and has totaled 238 yards in the last two games.
  • Lacey (275 yards 3 TD) is the only player with over 136 receiving yards.
  • The Thundering Hrrd are up against an ODU defense that ranks 13th against the pass but only 95th against the run.

Old Dominion vs. Marshall Carolina Pick

Spread Pick for ODU vs. Marshall

  • Old Dominion -14.5 (+4 Units)

Old Dominion has won four in a row since a loss in their opener and Marshall had won two in a row before losing their last game. The Thundering Herd have scored at least 42 points in their last two games, while the Monarchs have only given up seven points in each of their last two games. Marshall only has two wins, with one coming against an FCS team and the other against a team that currently only has one win. While ODU also beat an FCS team, they also have a road win over Virginia Tech from the ACC. Regarding the Old Dominion vs. Marshall prediction, the Monarchs will give up more than seven points to a good Marshall offense but their offense will kill it facing a suspect Thundering Herd defense, which is why they will cover the big spread on the road.

Over/Under Pick for ODU vs. Marshall

  • Over 57Β 

The total has gone Over for Marshall’s last two games and that is the pick I am leaning towards. The Thundering Herd have scored at least 42 points in each of their last two games. While they will be facing a solid Old Dominion defense, they will get their points since they will move the ball on the ground, facing a Monarchs defense that only ranks 95th in the nation against the run. Marshall will not light up the scoreboard, but Old Dominion will. They have scored at least 45 points in two of their last three games and will be facing a Thundering Herd defense that gave up 54 points in their last game and only ranks tied for 15th in the nation in points against per game. This game will see a lot of points scored, especially by ODU, which is why the Over is the pick.

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