Oregon Ducks vs Washington Huskies Prediction and Picks - November 29, 2025

By: Dean Whitaker Published 11/27/2025, 11:34 PM ET
Jordan Washington looks to lead the Huskies over the Ducks
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Big 10 Saturday afternoon, College football action, and we have an Oregon vs Washington prediction locked and loaded for you. The Ducks enter this contest off a 42-27 home win over USC, which moved them to 10-1 on the year. Washington comes in off a 48-14 road win over UCLA to move to 8-3 on the year. Can Washington play spoiler and kick Oregon out of the playoff picture? Read on to see our Oregon vs Washington prediction.

When it comes to college football selections, our College Football predictions are stellar.

Oregon Looks To Stay In Playoff Race

Oregon improved to 10-1 overall and 7-1 in Big Ten play after a 42-27 win over USC on November 22 in Eugene. Quarterback Dante Moore threw for 257 yards and two touchdowns, while tight end Kenyon Sadiq hauled in two scores. Running back Noah Whittington added 104 rushing yards and a touchdown, and wideout Malik Benson electrified the crowd with an 85-yard punt return for a score. The Ducks controlled the game with explosive plays and timely defense, keeping their College Football Playoff hopes alive heading into the rivalry clash with Washington.

Offensively, Oregon has been one of the most balanced attacks in the country, averaging 436 yards per game in the win over USC and consistently producing through both the air and ground. Moore has thrown for 2,447 yards and 23 touchdowns this season, spreading the ball to Sadiq and a deep receiving corps. Whittington has been steady in the backfield with 727 rushing yards and six scores, giving the Ducks a reliable option to complement their passing game. Oregon’s offensive line has provided protection and opened lanes, allowing the Ducks to dictate tempo against most opponents.

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Defensively, Oregon has shown resilience, holding USC to 382 total yards and forcing two turnovers. Linebacker Bryce Boettcher scored on a goal-line plunge after a penalty extended a drive, and the Ducks’ front seven limited USC’s rushing attack to just 30 yards from its lead back. Oregon’s defense has been opportunistic, with Boettcher leading the team in tackles (90) and Tui Tuioti contributing 5.5 sacks. Against Washington, the Ducks will need to maintain discipline against a balanced Huskies offense that has been surging in recent weeks.

Washington Destroys UCLA On The Road

Washington enters at 8-3 overall and 5-3 in Big Ten play, coming off a dominant 48-14 win over UCLA at the Rose Bowl on November 22. Quarterback Demond Williams Jr. accounted for four touchdowns — two through the air and two on the ground — while safety Alex McLaughlin returned a fumble 59 yards for a score. Running back Jonah Coleman added a short touchdown run, and wide receiver Decker DeGraaf capped the night with a 24-yard touchdown reception. The Huskies piled up 426 yards of offense and forced three turnovers, overwhelming the Bruins in every phase.

Offensively, Washington has been efficient and explosive, averaging 414.6 yards per game and 33.4 points per contest. Williams has thrown for 2,721 yards and 19 touchdowns, while also rushing for 11 scores, making him one of the most dynamic quarterbacks in the conference. Coleman has been the workhorse in the backfield with 651 rushing yards and 14 touchdowns, while wideout Denzel Boston leads the receiving corps with 730 yards and eight scores. The Huskies’ ability to mix power running with vertical passing has made them difficult to contain, especially when Williams is in rhythm.

Defensively, Washington has been stout, allowing just 17.5 points per game and 327 yards per outing. McLaughlin leads the secondary with 81 tackles, while edge rusher Jayden Lane has contributed 3.5 sacks. The Huskies forced three turnovers against UCLA, including McLaughlin’s scoop-and-score, and consistently pressured the Bruins into mistakes. Against Oregon, Washington will need to replicate that defensive intensity, focusing on limiting Moore’s passing lanes and containing Whittington on the ground. With the rivalry stakes high, the Huskies’ defense will be tested against one of the nation’s most balanced offenses.

Oregon vs Washington Pick

Oregon vs Washington Spread Pick

  • Washington +6.5 (4 Units)

Washington catching +6.5 feels like the right side because of how well their defense has been playing down the stretch. The Huskies are allowing just 17.5 points per game and have consistently forced turnovers, including three in their win over UCLA. That kind of defensive intensity matches up well against Oregon’s high-powered offense, giving Washington a chance to keep this rivalry game tight. With quarterback Demond Williams Jr. providing balance as both a passer and runner, and running back Jonah Coleman pounding out tough yards, Washington has the tools to sustain drives and shorten the game.

On the other side, Oregon has been explosive, averaging over 33 points per contest, but Washington’s ability to control tempo and limit possessions makes the +6.5 attractive. The Huskies have playmakers in the passing game like Denzel Boston and Chase Roberts, who can stretch the field and keep Oregon’s secondary honest. If Washington’s defense can slow down Dante Moore’s rhythm and force the Ducks into longer drives, the Huskies should be able to hang around. In a rivalry matchup with playoff implications, taking the points with Washington looks like a smart play.

Oregon vs Washington Over/Under Pick

  • Under 51.5 (4 Units)

The Under 51.5 looks like a strong angle because both Oregon and Washington bring defenses capable of limiting explosive plays, with the Ducks holding opponents to just over 20 points per game and the Huskies allowing only 17.5. Washington’s run-heavy approach with Jonah Coleman and Demond Williams Jr. tends to chew clock, while Oregon balances Dante Moore’s passing with Noah Whittington’s ground game to control tempo rather than push shootouts. In a rivalry matchup where possessions will be valued and mistakes minimized, the pace and defensive efficiency point toward a game that stays beneath 51.5.

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