Oregon vs Ohio State Picks and Prediction for Saturday November 7, 2026
The Oregon Ducks will be on the road Saturday afternoon for a massive Big Ten matchup against the Ohio State Buckeyes inside Ohio Stadium in Columbus, Ohio. The game is scheduled to kick off at 3:30 PM ET, with coverage available on CBS. Oregon comes into this matchup ranked No. 23 in the nation with a 5-3 record, having won three of its last five games following an eight-point home victory against Northwestern a week ago. The Ohio State Buckeyes return home Saturday ranked No. 12 in the country with six wins through their first eight games, following a 12-point road loss to USC last week that snapped their winning streak. Ohio State enters Saturday as a 7.5-point home favorite at -305 on the moneyline, while Oregon is listed at +245. The total for this Big Ten showdown is set at 46.5 points. Keep up with our College Football Picks.
Oregon looks for the huge win
Dylan Raiola leads the Oregon offense this season with 1,097 passing yards and nine touchdowns on 96 completions. Dante Moore completed 69 passes for 926 yards and nine touchdowns before suffering an injury. Brock Thomas has also contributed under center for Oregon, completing 23 passes for 226 yards and one touchdown. Jordan Davison is the top running back on the Oregon roster with 439 yards and seven touchdowns on 91 carries. Dierre Hill Jr. has added 399 yards and three scores on 83 carries. Dakorien Moore leads the Oregon receiving corps with 545 yards and six touchdowns on 41 receptions. Evan Stewart has chipped in 423 yards and four scores on 31 catches.
Defensively, Oregon did just enough last week, allowing 26 points on 456 total yards while limiting its opponent to seven third-down conversions to help secure the victory. Offensively, Oregon rolled, scoring 34 points, including 21 in the second half, on 441 total yards. Dylan Raiola led the Oregon offense, completing 22 passes for 336 yards and three touchdowns. Brandon Smith added a team-high 82 rushing yards and one touchdown on eight carries. Dakorien Moore lit it up through the air, compiling 128 receiving yards and two touchdowns on seven catches.
Ohio State tries to stay afloat
Julian Sayin has been the offensive leader for Ohio State this season, throwing for 2,007 yards and 19 touchdowns on 131 completions before suffering an injury. Luke Fahey has completed 30 passes for 463 yards and three touchdowns. Bo Jackson is the top ball carrier on the Ohio State roster with 637 yards and four touchdowns on 128 carries. Ja’Kobi Jackson has added 354 yards and a team-high six rushing touchdowns on 59 carries. Jeremiah Smith is the top target in the Ohio State offense with 1,067 yards and 13 touchdowns on 62 receptions. Devin McCuin has chipped in 285 yards and two scores on 20 catches.
Defensively, Ohio State struggled last week, allowing 30 points, including 20 in the first half, on 338 total yards. Offensively, Ohio State moved the ball well, compiling 464 total yards but scoring just 18 points after converting only seven third downs and turning the ball over once in the game. Luke Fahey led the Ohio State offense, completing 21 passes for 260 yards and one touchdown. Bo Jackson posted a team-high 121 rushing yards on 21 carries. Jeremiah Smith added 83 receiving yards and one touchdown on 10 catches.
Oregon vs Ohio State Picks and Prediction
Pick: Oregon Ducks 7.5
Oregon has the offensive talent and overall team speed necessary to challenge Ohio State in this matchup. The Ducks should be able to generate opportunities by spreading the field and forcing the Buckeyes to defend multiple offensive threats. Ohio State has plenty of talent on both sides of the football, but Oregon could find success by establishing an aggressive offensive rhythm and avoiding predictable passing situations. The Ducks will also need to create defensive pressure and force Ohio State into difficult third-down situations. Look for Oregon to rely on its offensive versatility and ability to create explosive plays to keep this game close with a legitimate opportunity to secure the road upset.
Total Pick: Under 46.5
Both teams have enough offensive talent to produce points, but the importance of this matchup could lead to a more conservative approach at times. Ohio State has the defensive personnel necessary to challenge Oregon's offensive rhythm, while the Ducks should look to limit explosive plays and force the Buckeyes into long possessions. Both teams will need to protect the football and avoid giving their opponent short fields. Expect a physical matchup with defensive adjustments playing a major role as the game progresses. Look for both defenses to make enough stops to keep this matchup under the total.