Purdue Boilermakers vs Washington Huskies Prediction and Picks - November 15, 2025

By: Dean Whitaker Published 11/13/2025, 06:40 PM ET
Demond Williams Jr. looks to lead the Huskies over the Boilermakers
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Big 10 college football action on Saturday evening, and we have a Purdue vs Washington prediction locked and loaded for you. It has been a rough season for the Boilermakers as they come in at 2-8 overall and 0-7 in league play. Washington comes in with a 6-3 record overall, while going 3-3 in league play. Can Purdue at least keep this one close? Read on to see our Purdue vs Washington prediction.

When it comes to college football selections, our College Football predictions are stellar.

The Long Season Continues For Purdue

Purdue comes into this game at 2–8, fresh off a 34–10 loss to Ohio State that highlighted just how much this team has struggled to find rhythm. Quarterback Ryan Browne has had an up-and-down season, throwing for just under 1,900 yards with nine touchdowns and eight interceptions. Against the Buckeyes, he managed only 76 passing yards and an interception, leaving the offense sputtering. Running back Antonio Harris has shown flashes, rushing for 45 yards last week, but the ground game hasn’t been consistent enough to take pressure off Browne. The Boilermakers average just 20.9 points per game, ranking near the bottom nationally, and they’ve been plagued by turnovers with 17 giveaways this season.

The offense has been a mix of short gains and stalled drives, averaging only 357 yards per game. Their passing attack sits middle of the pack nationally, but the lack of explosive plays has hurt them. Wideouts like Rico Walker and Michael Jackson III have provided occasional sparks, but Purdue has struggled to finish drives, ranking near the bottom in red-zone efficiency. Against Washington’s defense, which has been stingy against the run, Purdue will need to find ways to stretch the field and create mismatches. Without that, they risk falling behind early and being forced into a one-dimensional attack.

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Defensively, Purdue has had its share of issues, giving up nearly 28 points per game and over 400 yards of total offense. They’ve been particularly vulnerable against the pass, allowing 234 yards per game, and opponents have converted over 40% of their third downs. The front seven has been inconsistent, surrendering 160 rushing yards per contest, which makes it difficult to control tempo. The Boilermakers have fought hard, but the lack of depth and discipline has shown up week after week. Against Washington’s balanced offense, Purdue will need to force turnovers and shorten the game if they want to keep this competitive.

Huskies Struggle On Offense In Loss To Wisconsin

Washington enters at 6–3, still ranked in the Top 25 despite a tough 13–10 loss to Wisconsin last week. Quarterback Demond Williams Jr. has been the leader of this offense, throwing for over 2,200 yards with 15 touchdowns and completing nearly 72% of his passes. He struggled against the Badgers, finishing with 134 yards and an interception, but his dual-threat ability remains a weapon—he added 61 rushing yards in that game. Running back Jonah Coleman has been a steady force, scoring 13 touchdowns on the season, while wideout Denzel Boston has emerged as the go-to target with 730 receiving yards and eight scores.

The Huskies’ offense has been one of the most efficient in the conference, averaging 32.7 points per game and over 417 yards of total offense. They thrive on balance, with Coleman pounding the ball inside and Williams spreading it around through the air. Washington ranks among the nation’s best in third-down conversions, moving the chains on over 51% of attempts, which keeps drives alive and wears down defenses. Against Purdue’s struggling secondary, expect the Huskies to test deep shots early and lean on Boston to stretch the field. If Williams settles in, this offense has the firepower to put the game out of reach quickly.

Defensively, Washington has been solid, allowing just 20 points per game and ranking top 30 nationally in total defense. They’ve been particularly strong against the run, giving up only 109 yards per contest, which matches up well against Purdue’s inconsistent ground game. The secondary has been steady, holding opponents under 210 passing yards per game, and their ability to get off the field on third downs has been a difference-maker. After the disappointment against Wisconsin, the Huskies will be motivated to bounce back at home, and their defense should set the tone early. With the combination of offensive balance and defensive discipline, Washington looks well-positioned to handle business against a Purdue team that’s been searching for answers all season.

Purdue vs Washington Pick

Purdue vs Washington Spread Pick

  • Washington -17 (2 Units)

Washington -17 looks like the right side because the Huskies’ defense matches up perfectly against Purdue’s weaknesses. The Boilermakers have struggled to generate any consistent offense, averaging just over 20 points per game and ranking near the bottom nationally in red-zone efficiency. Ryan Browne has been turnover-prone, and Purdue’s ground game hasn’t been strong enough to take pressure off him. Washington, meanwhile, is holding opponents to only 20 points per game and has been excellent against the run, giving up just 109 yards per contest. That combination should allow the Huskies to control tempo, force Purdue into predictable passing downs, and create opportunities for their pass rush to take over.

On the other side of the ball, Washington has the balance to pull away and cover a big number. Demond Williams Jr. has been efficient all season, completing over 70% of his passes, while Jonah Coleman provides a reliable rushing attack that keeps defenses honest. Wideout Denzel Boston has emerged as a big-play threat, and against a Purdue secondary that’s been giving up over 230 passing yards per game, the Huskies should find plenty of opportunities downfield. Playing at home after a tough loss to Wisconsin, Washington has both the motivation and the talent to bounce back in a big way. With their defense limiting Purdue’s scoring chances and their offense capable of piling up points, laying 17 feels justified.

Purdue vs Washington Over/Under Pick

  • Under 53 (2 Units)

The Under 53 looks like a solid angle because Washington’s defense has been one of the most reliable units in the conference, holding opponents to just 20 points per game and shutting down the run. Purdue, on the other hand, has struggled to generate offense all season, averaging barely 21 points and ranking near the bottom in red-zone efficiency. With the Huskies likely to control tempo and force the Boilermakers into long, inefficient drives, this matchup sets up for fewer possessions and limited scoring opportunities. Add in Washington’s ability to grind clock with Jonah Coleman on the ground, and the total feels inflated for what projects as a more controlled, lower-scoring game.

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