Rutgers vs. Purdue Prediction and Picks for Saturday, October 25th, 2025

By: Trenton Pruitt Published 10/23/2025, 06:28 PM ET
Rutgers vs. Purdue Prediction
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Neither of these teams are playing for a conference title in 2025, but this should still be a fun Big Ten tilt as the Purdue Boilermakers (2-5, 0-4 B1G) gear up to host the Rutgers Scarlet Knights (3-4, 0-4 B1G). We’ve got you covered with our Rutgers vs. Purdue prediction. Kickoff is scheduled for 12:00 ET from Ross-Ade Stadium in West Lafayette, IN. Don’t get sacked this football season! Try our College Football Picks!

Scarlet Knights Drop Fourth Straight Game

This is Coach Greg Schiano’s 17th season leading the Rutgers Scarlet Knights, but the program has fallen flat on its face after a promising 3-0 start in 2025. Once Big Ten play rolled around, the Scarlet Knights dropped four straight games and now sit at 3-4. Those four conference losses came at the hands of Iowa (38-28), Minnesota (31-28), Washington (38-19), and #8 Oregon (56-10), most recently. From a sports betting perspective, Rutgers is 3-4 ATS and 6-1 to the over.

Veteran quarterback Athan Kaliakmanis is leading the offense this season, and he has looked solid. The signal caller has thrown for 1,864 yards on a 62.4% completion rate, adding 11 touchdowns and five interceptions. Kaliakmanis’ favorite option out wide has been WR Ian Strong, who has 543 yards and two touchdowns on 37 receptions. RB Antwan Raymond has handled a bulk of the rushing workload, gaining 615 yards and nine touchdowns on 120 carries (5.1 YPC).

  • Offensively, the Scarlet Knights are scoring 27.3 points per game (62nd), while averaging 384.7 yards per week (66th).
  • Defensively, they are 119th in the country this year, conceding 35.2 points per game. They’re allowing 474.2 yards per contest, which is 129th.

Boilermakers 0-5 in Last Five Games

This is Coach Barry Odom’s first season as the head coach of the Purdue Boilermakers football program, and he’s having a tough time getting accustomed to the Big Ten. After a solid 2-0 non-conference start, the Boilermakers have now dropped five straight games. The recent string of losses for Purdue have come against USC (33-17), #24 Notre Dame (56-30), #22 Illinois (43-27), Minnesota (27-20), and Northwestern (19-0), most recently. At 0-4 in Big Ten play, the Boilermakers are in the cellar of the conference. Purdue is 3-4 ATS and 5-2 to the under.

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QB Ryan Browne is still dealing with a shoulder injury and is listed as doubtful, which means we will likely see backup QB Malachi Singleton back in the saddle on Saturday. Singleton has thrown for 255 yards on a 57.1% completion rate, adding one touchdown and two picks. He does have an additional 142 rushing yards and a touchdown on 25 carries (5.7 YPC) this year. RB Devin Mockobee is the lead rusher with 430 yards and four touchdowns on 109 totes (3.9 YPC). WR Michael Jackson III (390 yards, 1 TD) leads things out wide in the passing attack.

  • Purdue’s offense has been subpar this season, ranking 99th in scoring (20.8 PPG), while putting up 397.2 yards per game (50th).
  • On the defensive side, the Boilermakers are 94th this season, allowing 29.7 points per game. In terms of yardage, they’re 76th, conceding 389.2 yards per contest.

Rutgers vs. Purdue Pick

Spread Pick for Rutgers vs. Purdue

  • Rutgers Scarlet Knights -2.0 (-110) (5 units)

Both of these schools are searching for their first Big Ten wins of the year, and I think it’ll be Rutgers who finally gets off the schneid and secures a win.

For me, the Scarlet Knights just seem to have the higher ceiling on the offensive side of the ball with a veteran quarterback in Athan Kaliakmanis. Plus, the Boilermakers will likely turn to a backup quarterback in Malachi Singleton on Saturday. He leads a Purdue squad that’s just 5-13 ATS in its last 18 games overall, as well as 2-7 ATS in its last nine home games specifically.

Over/Under Pick for Rutgers vs. Purdue

  • Under 58.5 (-108) (5 units)

These defenses both have a ton of issues, and I think we’ll see some scoring on Saturday afternoon, but we do have to draw the line somewhere in regard to the total. 58.5 points is pretty lofty, so I’m going to buy back and lock in the under. For Purdue, they’re coming off of a 19-0 shutout loss against Northwestern with Singleton under center. The backup QB has posted a 57.1% completion rate this year, and, being that we have one game where they were blanked as a data point, I just can’t get on board with an over in this spot. Purdue is 5-2 to the under this season, and that’s a trend that I expect to continue.

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