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Southern Miss Golden Eagles vs. Louisiana Tech Bulldogs Picks and Prediction for Saturday, September 20, 2025

By: Robert Antuann Published 09/18/2025, 05:14 PM ET
Southern Miss Golden Eagles at Louisiana Tech Bulldogs Picks and Prediction for Saturday, September 20, 2025

We have an exciting non-conference game for Week 4 of the college football season as the Southern Miss Golden Eagles are traveling to Jope Aillet Stadium in Ruston, Louisiana on Saturday evening to take on the Louisiana Tech Bulldogs in our Golden Eagles vs. Bulldogs prediction. The game is airing exclusively on ESPN+, so this game is going to be intriguing as both teams are entering with a 2-1 record. The Golden Eagles (2-1) are on a two-game winning streak after a 38-2 home win over the Appalachian State Mountaineers on Saturday. The Bulldogs (2-1) are coming off Saturday’s dominant 49-14 home win over the New Mexico State Aggies.Before kickoff: NCAAF predictions for Southern Miss Golden Eagles at Louisiana Tech Bulldogs in one clean snapshot.

Golden Eagles Ready to Extend Their Winning Streak

The Southern Miss Golden Eagles are looking to open the season on a strong note as they are now 2-1 heading into this game, as they attempt to extend their winning streak. The Golden Eagles are middling offensively as they are tied for 66th in the sport with 31.0 points per game right now. Quarterback Braylon Braxton has been playing stepping up throughout the season as he has completed 68-of-99 (68.7%) of his passes for 692 yards with seven passing touchdowns to two interceptions. The running game has running back Jeffrey Pittman leading the way as he has recorded 25 rushing attempts for 126 yards (5.0 yards per carry) with a pair of rushing touchdowns but also has been involved in the passing game with 10 catches for 62 yards (6.2 yards per reception) but has not found the end zone as a receiver.

The defense of the Southern Miss Golden Eagles has been struggling a bit as they are tied for 89th in college football as they are allowing 25.3 points per game. Southern Miss is getting pressure and forcing mistakes as they have tallied nine sacks, six interceptions (one returned for a touchdown), a forced fumble, and zero fumble recoveries. If the defense can continue to improve and get stops, it will be in a good position to keep winning games.

Injury Report for Southern Miss

No injuries to report

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Bulldogs Showing Their Bark

The Louisiana Tech Bulldogs need to keep winning if they want to be a force this year. Louisiana Tech has been scoring at a good level as they are tied for 68th in the country with 30.7 points per game so far. Quarterback Blake Baker took over for a struggling Trey Kukuk last week and seemingly is in line for the start here as he has completed 11-of-24 (45.8%) of his passes for 228 yards with a pair of passing touchdowns and zero interceptions while running 21 times for 116 yards (5.5 yards per attempt) with a rushing touchdown.

The defense for the Bulldogs has been playing at an elite level as they are giving up 12.3 points per game, which is tied for 23rd in college football. Their defense has been able to apply pressure and force turnovers as they have eight sacks, four forced fumbles, two fumble recoveries, and five interceptions.

Injury Report for Louisiana Tech

  • Quarterback Trey Kukuk: Undisclosed (Questionable)
  • Wide receiver Jay Wilkerson: Undisclosed (Questionable)

Southern Miss Golden Eagles at Louisiana Tech Bulldogs Pick

Spread Pick for Southern Miss Golden Eagles at Louisiana Tech Bulldogs

  • Southern Miss Golden Eagles +145 (4 units)

The Southern Miss Golden Eagles seemingly have stability at the quarterback position, while the Louisiana Tech Bulldogs have not. With the uncertainty of Kukuc or Baker under center, there seemingly is a ceiling of what to expect out of the Bulldogs' offense. The defense is going to be able to keep Louisiana Tech in the game, but the amount of points the team can score is questionable. Southern Miss looks like a well-oiled machine offensively and should continue to do just that. All in all, take the Southern Miss Golden Eagles to win this game as a road underdog.

Over/Under Pick for Southern Miss Golden Eagles at Louisiana Tech Bulldogs

  • Under 50.5 (4 units)

Just like the spread, the quarterback uncertainty for the home team leaves way too many question marks to be comfortable with the over. Braylon Braxton could score the football, but the Golden Eagles can play a good brand of defense as a result of the uncertainty. Southern Miss’ defense is going to get stops and slow down Louisiana Tech and Louisiana Tech’s defense should do the same. Take the under to hit here.

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