Texas A&M Aggies vs. Missouri Tigers, Preview, Odds, Picks and Prediction, Saturday November 8, 2025
The College Football season has seen some high-profile matchups already, and on Saturday, we'll see yet another with our Texas A&M Aggies vs. Missouri Tigers prediction.
The No. 3 Texas A&M Aggies (8-0) have been dominant from the first snap of the 2025 season, and with two impressive, ranked wins on their resume already, they'll be looking to make yet another big statement in this matchup.
On Saturday, they take on the 22 Missouri Tigers (6-2), a team that's dropped two of their last three games, but with an opportunity against one of the best teams in the nation, they could begin climbing the ranks once again with another victory. Read on to see our Texas A&M Aggies vs. Missouri Tigers prediction. If you are struggling to pick winners, you've come to the right place. We have the strongest College Football Picks.
Can Texas A&M remain undefeated?
The third-ranked Texas A&M Aggies have been dominant from the moment 2025 began, and with the team going 3-0 on the road thus far, including two wins over ranked opponents, they've truly earned themselves a spot among the elite teams in the nation. Offense has been the biggest strength of this Aggies team thus far in 2025, as they average 460 yards a game to go along with 38 points, ranking them 14th in the nation, and with a defense that limits opponents to just 24 a game and 321.5 total yards, they're as balanced as any in college football.
This success all comes on the back of sophomore QB Marcel Reed, who has thrown for 17 touchdowns this season and rushed for a further six, and with the running game tallying 19 overall scores on the ground, this is a team set for greatness in 2025.
Last time out for the Aggies was a dominant win over the 20th-ranked LSU Tigers on October 25, with 224 yards and four scores on the ground leading the way as the defense limited their opponents to just 278 yards, coming away winners 49-25 in the process.
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Can Missouri pick up a much-needed upset?
The 22 Missouri Tigers entered the 2025 season full of hope, but after a five-game winning streak to start the year, they've dropped two of their last three as they've now fallen to No. 22 in the College Football standings this season. This is also one of the more balanced teams in the nation, as the Tigers rank fifth in the NCAA in yards allowed at 245 per game while giving up just 17 points, and given that their offense averages 35 points a game, it's easy to see why they're still so optimistic about this season.
| # | Handicapper | Profit |
|---|---|---|
| 1 |  Rob Vincilleti | +450.00 |
| 2 |  Sean Higgs | +327.00 |
| 3 |  David Delano | +182.00 |
| 4 |  Stephen Nover | +100.00 |
| 5 |  Terry Edelmann | +100.00 |
Most of Missouri's success comes from a run game that has combined to put up over 1,800 rushing yards thus far, with starter Ahmad Hardy tallying 11 scores on the year. Beau Pribula (dislocated ankle) was injured in their last game against Vanderbilt (a 17-10 loss on Oct. 25). The Mizzou defense limited Vandy to 265 yards while forcing one turnover, but came up short in a defensive struggle.
Enter freshman Matt Zollers, who will make his first career start. Zoller stepped in for Pribula after the injury and completed 14 of 23 for 138 yards and a TD against Vandy. He'll need some help from Hardy, who has 937 rushing yards and 11 rushing touchdowns this season. He came into that game having attempted just six passes on the season.
Texas A&M Aggies vs. Missouri Tigers picks
Moneyline pick for Texas A&M vs. Missouri
- Texas A&M -7 (4 units)
This matchup should be one of the games of the week in College Football, and despite being the road team, the Aggies come into this one as a tight favorite on the back of a 3-0 mark this season away from home.
On top of that, the Tigers have lost both of their matchups against ranked opponents this season, and with Texas A&M firing on both sides of the ball as of late, expect them to pick up yet another statement victory on the road. Mizzou will be without Pribula, as Zollers will have a tough time in his first start against a strong SEC defense. That defense holds teams to just 119 yards per game on the ground and 3.9 yards per carry. It will be tough for the Tigers to get anything going offensively.
Over/under pick for Texas A&M vs. Missouri
- Over 48 (4 units)
On paper, this one could go either way, as these two teams have elite-level units on both sides of the ball, but after 51 points were scored in their last head-to-head encounter in 2024, this one should be just as high scoring.
For the Aggies, the over sits at 7-3 in their last 10 overall games, with 40 or more points scored in all three of their road games this season, and for the Tigers, the over comes in at 5-5 in their past 10, with 30 or more points scored in five of their six home games this year. Expect some turnovers from the Tigers with a freshman QB going up against an elite defense and that will put the Aggies in scoring position.
Keep it simple, take the over.
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