UCLA vs Oregon Picks and Prediction for Saturday October 10, 2026

The UCLA Bruins will travel north Saturday afternoon for a Big Ten matchup in Eugene, Oregon, against the Oregon Ducks. Kickoff is scheduled for 3:30 PM with coverage on CBS. UCLA enters the weekend ranked No. 21 nationally with a perfect 4-0 record and will face one of its toughest challenges of the season. The Bruins will look to remain undefeated and pick up a significant conference victory on the road. Oregon comes into the game ranked No. 13 nationally with a 3-1 record and will look to use its home-field advantage to get past another ranked opponent. The Ducks have an opportunity to strengthen their position in the Big Ten standings with a victory. Oregon is a 10.5-point favorite, with the total set at 58.5 points. The Ducks are -410 on the money line, while UCLA comes in at +320.  Stay up to date with our College Football Picks.

UCLA tries to stay unbeaten

Nico Iamaleava leads the UCLA offense this season with 820 passing yards and four touchdowns on 62 completions, along with 143 rushing yards and one touchdown on 35 carries. Wayne Knight leads the Bruins rushing attack with 445 yards and nine touchdowns on 49 carries. Anthony Woods has added 269 yards and four touchdowns on 36 carries, while Jaivian Thomas has chipped in 155 yards and three scores on 28 carries. Semaj Morgan leads all UCLA receivers with 174 yards and two touchdowns on 14 catches. Brian Rowe Jr. has added 163 yards on 11 receptions, while Knight has contributed 88 receiving yards on eight catches.

Offensively, UCLA dominated a week ago, scoring 54 points on 475 total yards. Defensively, UCLA was even better, giving up three points on 181 total yards after allowing just one third-down conversion and forcing 5 turnovers in the win.  Nico Iamaleava led the UCLA offense last week, completing 15 passes for 209 yards and one score in the game. Wayne Knight was the top ball carrier on the team with 100 yards and one touchdown on 10 carries. Troy Leigber added 83 yards and one score on five carries, and Anthony Woods chipped in seven carries for 41 yards and one touchdown.  Aidan Mizell led the team with 83 yards and one touchdown on one reception.

Oregon looks to defend their field

Dante Moore leads the Oregon offense this season with 926 passing yards and nine touchdowns on 69 completions. Dylan Raiola has added 413 passing yards and five touchdowns on 30 completions. Jordon Davison leads the Ducks rushing attack with 260 yards and five touchdowns on 49 carries. Dierre Hill Jr. has added 184 yards and three touchdowns on 42 carries, while Brandon Smith has chipped in 85 yards and one score on 16 carries. Evan Stewart leads all Oregon receivers with 278 yards and three touchdowns on 22 catches. Dakorien Moore has added 234 yards and four touchdowns on 14 receptions, while Jamari Johnson has contributed 176 yards and one score on 11 catches.

The Oregon Ducks' offense was phenomenal a week ago, scoring 41 points, including 28 in the second half, on 504 total yards. Defensively, Oregon was shaky, giving up 27 points on 446 total yards but forcing one turnover to seal the victory. Dylan Raiola led the way for Oregon a week ago, completing 19 passes for 280 yards and two scores. Jordon Davison led the way on the ground with 66 yards and one touchdown on 16 carries. Dierre Hill Jr. added 63 yards and two touchdowns on 15 carries. Jamari Johnson led all Oregon receivers with 119 yards on 7 catches.

UCLA vs Oregon Picks and Prediction

Pick: Oregon Ducks -10.5 (-108)

Oregon has an opportunity to pick up a big conference victory Saturday when undefeated UCLA travels to Eugene. The Bruins have been impressive to start the season and should provide a difficult challenge for the Ducks. UCLA will need to find success offensively and avoid allowing Oregon to build an early lead. The Ducks have plenty of talent on both sides of the football and should benefit from playing in front of their home crowd. Oregon will need to limit turnovers and take advantage of its scoring opportunities against a confident UCLA team. The Bruins should have their moments offensively, but Oregon has the overall talent and home-field advantage to take control and hand UCLA its first loss of the season.

Pick: Over 58.5 (-105)

There should be plenty of offensive opportunities Saturday afternoon when UCLA and Oregon meet in Eugene. Both teams have the ability to move the football and create big plays, which could lead to a high-scoring conference matchup. UCLA will need to put points on the board to keep pace with an Oregon team that can score quickly when its offense gets going. The Ducks should look to attack the Bruins' defense and take advantage of their opportunities in the passing game. UCLA also has enough offensive talent to contribute to the scoring and prevent Oregon from completely taking over. Look for both teams to find success moving the football and push the combined score beyond the posted total.

Final Picks: Oregon Ducks -10.5 (-108) and Over 58.5 (-105)