UNLV Rebels vs. Wyoming Cowboys Picks and Prediction for Saturday, October 4, 2025
Use Code SSWC The UNLV Rebels (4-0, 0-0 MWC) are looking dominant right now as they are coming off a 41-38 road win over the Miami RedHawks on Sept. 20. Junior quarterback Anthony Colandrea had a good game as he completed 29-of-43 passes for 293 yards with two passing touchdowns and two interceptions as well as 16 rushing attempts for 54 yards (3.4 yards per carry).
The Wyoming Cowboys (2-2, 0-0) are doing a respectable job thus far, but they are on a two-game losing streak as they are coming off a 37-20 road loss against the Colorado Buffaloes on Sept. 20. Sophomore quarterback Kaden Anderson struggled a bit as he completed 11-of-25 passes for 176 yards with a pair of touchdowns.
Rivalries, tempo, trenches — NCAAF picks for UNLV Rebels vs. Wyoming Cowboys.
Rebels 5-0 Start?
The UNLV Rebels are coming off a 41-38 win on the road against the Miami-Ohio RedHawks last game. UNLV was able to score 41 points on 515 total yards (293 passing, 222 rushing). The offense was able to move the football without issues as they were 12-for-17 on third downs and recorded 30 first downs as a team. They were also able to run the ball at an incredible rate, averaging 5.2 yards per rushing attempt. However, they had two interceptions on the day. The Rebels have now beaten UCLA, Sam Houston State, FCS Idaho State to start the season along with Miami-Ohio.
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The defense was brutal as they gave up 38 points on 396 total yards (265 passing, 131 rushing) in the game. The defense was able to force three turnovers (two interceptions, one fumble) in the game and really shut down drives as they limited the RedHawks to 1-for-9 on third down and 1-for-1 on fourth downs.
Anthony Colandrea is completing 71.6% of his passes for 940 yards with eight TDs and three INTs. He has also rushed for 229 yards (5.1ypc) with one TD.
UNLV’s offense has dominated as they are 33rd in college football with 36.8 points per game. Their defense needs to improve as their 28.2 points per game allowed ranks 103rd in the nation.
Injury Report for UNLV
- Quarterback Alex Orji: Undisclosed (OUT)
Cowboys Ready to Get Back in the Win Column
The Wyoming Cowboys are looking to recover from their last game as they lost on the road against the Colorado Buffaloes 37-20 two weeks ago. The offense finished with 20 points on 347 total yards (182 passing, 165 rushing). The team was able to step up without turning the ball over and moved it well, averaging 7.0 yards per pass and 4.0 yards per carry. That los to the Buffaloes came after a 31-6 defeat at home against Utah. The Cowboys opened the season with wins over FCS Northern Iowa and Akron.
The defense was not good as they held Colorado to 37 points on 497 total yards of offense (304 passing, 193 rushing). The team was unable to get stops on the money downs as the Buffs were to 5-for-10 on third down. The Cowboys forced one fumble and recovered it as well.
The Wyoming Cowboys have been unable to score too many points as they are 126th in the nation with 16.8 points per game. Their defense has been clicking as they are giving up 18.8 points per game, which is 39th in college football.
Quarterback Kaden Anderson is completing 55.1% of his passes for 711 yards with five TDs and two interceptions. He's not a threat to run as he has -44 yards rushing.
Injury Report for Wyoming
- Running back Nico Hamilton: Arm (Questionable)
- Tight end John Michael Gyllenborg Undisclosed (Questionable)
- Running back Patrick Broadway II: Knee (OUT)
- Defensive end Caleb Robinson: Achilles (OUT)
- Defensive tackle Dante Drake: Achilles (OUT)
- Offensive lineman Nathan Geiger: Knee (OUT)
UNLV Rebels vs. Wyoming Cowboys Pick
Spread Pick for UNLV vs. Wyoming Cowboys
- UNLV Rebels -175 (4 units)
UNLV is the healthier and better team, so take them to win on the road convincingly. They understand how to get it done on the road. The ability to simply complete passes keeps an offense flowing and there is a significant gap here as the Rebels are 12th in the nation with a 73.0 completion percentage, while the Cowboys are down at 118th with only a 56.8 completion percentage right now. The significant difference offensively is going to be the difference in this clash.
Over/Under Pick for UNLV vs. Wyoming Cowboys
- OVER 49.5 (5 units)
These teams have been humming offensively as of late, with the Rebels scoring 35.5 points in their last two games while the Cowboys are averaging 19.0 points in their previous three outings. Both teams are excellent on third downs this season as UNLV is 25-of-48 (52.08%) so far while Wyoming is a respectable 21-of-55 (38.18%) up to this point. All in all, go with OVER 49.5 POINTS as the better bet to make for this game. These teams have gone over in four of their last five meetings.
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