Washington Huskies vs UCLA Bruins Prediction and Picks - November 22, 2025
Use Code SSWC Saturday evening Big 10 College football action, and we have a Washington vs UCLA prediction locked and loaded for you. The Huskies come in off a 49-13 destruction of Purdue at home to move to 7-3 on the year. The rough season for the Bruins continues as they are now 3-7 on the year after a 48-10 loss to Ohio State on the road. Washington won last year's meeting at home by a score of 31-19. Read on to see our Washington vs UCLA prediction.
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Washington Bounces Back Big
Washington bounced back in a big way last weekend, rolling past Purdue 49-13 at Husky Stadium last week. Quarterback Demond Williams Jr. was nearly flawless, completing 16 of 19 passes for 257 yards and two touchdowns, while also adding 23 rushing yards. Running back Jordan Washington broke free for a 68-yard score, and Adam Mohammed punched in three rushing touchdowns to pace the ground game. The Huskies piled up 506 total yards and forced Purdue into sloppy mistakes, showing the kind of balance that has kept them in the Big Ten race.
Williams has been the steady hand all season, throwing for 2,508 yards with 17 touchdowns against just five interceptions, while also rushing for 513 yards and four scores. Jonah Coleman has been the workhorse in the backfield with 645 rushing yards and 13 touchdowns, and Mohammed has chipped in 304 yards and five scores. Through the air, Denzel Boston (730 yards, 8 TDs) has been the go-to target, while Dezmen Roebuck (431 yards, 5 TDs) and Decker DeGraaf (281 yards, 1 TD) provide depth. Washington averages 34.3 points per game, ranking 25th nationally, and their ability to spread the ball around makes them difficult to defend.
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Defensively, the Huskies have been one of the most reliable units in the conference, allowing just 313.7 yards per game and 19.3 points per contest. Their run defense has been stout, giving up only 107.9 yards per game, while the secondary has held opponents to 205.8 passing yards. With nine takeaways, Washington has shown the ability to flip momentum, and their overall discipline has kept them in tight games. Heading into Pasadena, the Huskies will look to continue their strong play on both sides of the ball as they chase a spot in the upper tier of the Big Ten standings.
UCLA Crushed By The Buckeyes
UCLA’s last trip to the field was a tough one, as they were overwhelmed by No. 1 Ohio State in Columbus, falling 48-10 on November 15, 2025. Quarterback Luke Duncan completed 16 of 23 passes for 154 yards and a touchdown, but the Bruins managed just 294 total yards against the Buckeyes’ suffocating defense. The lone bright spot came on a scoring strike to Kameron Gilmer, but the game was largely one-sided as Ohio State controlled the line of scrimmage and forced UCLA into long, unproductive drives.
The Bruins’ offense has struggled all season, averaging just 19.4 points per game. Quarterback Nico Iamaleava has thrown for 1,659 yards with 12 touchdowns but also seven interceptions, while adding 474 rushing yards and four scores. He is questionable for this one (concussion). If he can't go, then it will be Duncan again. The rushing attack has been inconsistent, with Jalen Berger (281 yards, 2 TDs) and Anthony Woods (252 yards) splitting carries, while Iamaleava’s mobility has been the most reliable source of production. In the passing game, Gilmer (432 yards, 3 TDs) and Titus Mokiao-Atimalala (251 yards, 3 TDs) have been the top options, but the lack of explosive plays has limited UCLA’s ability to keep pace with stronger opponents.
Defensively, UCLA has been porous, allowing 383 yards per game and 32.4 points per contest. Their pass defense has been respectable, ranking 25th nationally at 188.8 yards allowed, but the run defense has been a major weakness, giving up 194.2 yards per game. With only three takeaways all season, the Bruins have struggled to create momentum-shifting plays, leaving their offense to fight uphill battles. Facing Washington, UCLA will need Iamaleava to protect the ball and the defense to find ways to slow down Coleman and Williams, or else risk another lopsided defeat in front of the Rose Bowl crowd.
Washington vs UCLA Pick
Washington vs UCLA Spread Pick
- Washington -10.5 (3 Units)
Washington -10.5 looks like the right side because the Huskies have been dominant on both sides of the ball. Quarterback Demond Williams Jr. has completed over 72% of his passes for 2,508 yards and 17 touchdowns, while also rushing for 513 yards, giving Washington a balanced attack that averages 34.3 points per game. Running back Jonah Coleman has been a touchdown machine with 13 scores, and wideout Denzel Boston has emerged as a reliable deep threat with 730 yards and eight touchdowns. Against a UCLA defense that’s giving up 32.4 points per game and ranks 120th nationally against the run, Washington’s offense should be able to dictate tempo and pull away.
The Huskies’ defense makes the spread even more appealing. They rank 18th nationally in total defense, allowing just 313.7 yards per game, and have been especially stout against the run at 107.9 yards allowed. UCLA, meanwhile, has struggled to find consistency, averaging only 19.4 points per game with quarterback Nico Iamaleava battling through concussion issues. Even if he suits up, the Bruins’ offense has been mistake-prone and one-dimensional, while Washington has the personnel to pressure him and force turnovers. With the Huskies’ balance and UCLA’s struggles, laying the 10.5 points feels justified in a matchup that tilts heavily toward Washington
Washington vs UCLA Over/Under Pick
- Under 51.5 (3 Units)
The Under 51.5 makes sense because Washington’s defense has been one of the best in the country, allowing just 19.3 points per game and holding opponents under 315 total yards on average. UCLA’s offense, meanwhile, has struggled all season, producing only 19.4 points per game and ranking outside the top 100 nationally in passing. Even if Nico Iamaleava plays, the Bruins’ attack has been inconsistent and turnover-prone, while Washington’s balanced offense is more likely to control tempo than push for a shootout. With the Huskies’ ability to limit big plays and UCLA’s lack of scoring punch, this matchup profiles as a lower-scoring contest that stays beneath the number.
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