Los Angeles Dodgers vs. Baltimore Orioles Prediction and Picks - September 5, 2025

By: Anthony Leute Published 09/05/2025, 11:22 AM ET
Dodgers versus Orioles Prediction
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The Dodgers are traveling to Oriole Park at Camden Yards in Baltimore, Maryland for their series against the Orioles; keep reading for our Dodgers versus Orioles Prediction. Los Angeles is at the top of the NL West with a record of 78-62. Baltimore is last in the AL East with a record of 64-76. The Dodgers had a record of 2-1 versus the Orioles in 2024. The first pitch is scheduled for 7:05 p.m. EDT.

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Dodgers Look To Retain Top Spot 

The Dodgers are coming off another loss on Thursday versus the Pirates with a final score of 5-3. This would be the third loss in a row for the Dodgers and would allow the Pirates to sweep them in their series. Los Angeles sits at the top of their division; however, they have a winning percentage of only .557, and the Padres are creeping in on them with a winning percentage of .543.

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Los Angeles is looking to retain their lead spot in their division; however, due to recent struggles at the plate, they have been unable to grab the wins needed to secure their position. On the season the Dodgers are third overall in runs and are eighth in batting average at .252. In their last six games however the Dodgers have only averaged 2.67 runs per game and had a batting average of only .223. This decline in their offense has made it difficult to generate wins and, as a result, put their playoff position in jeopardy.

Right-handed pitcher Tyler Glasnow will be taking the mound for the Dodgers on Friday.

Tyler Glasnow:

  • has a 1-3 record with an ERA of 3.41 and 81 strikeouts in 14 appearances this season.
  • is 4-2 with an ERA of 3.96 and 68 strikeouts in 9 appearances versus the Orioles in his career.

 

 

Orioles Look To Continue Win Streak

The Orioles picked up another win on Wednesday versus the Padres with a final score of 7-5. This is the third win in a row for the Orioles and would sweep their series against the Padres 3-0. Baltimore is far removed from their chance of making the playoffs however have been producing more wins as they rotate more rookies in their lineup.

The offense for the Orioles has been the weak point of the team for most of the season as they rank 17th overall in runs and 21st overall in batting average at .242. However in recent games we have seen a spike in their offensive output and have seen more wins as a result. Almost opposite to the Dodgers, the Orioles have averaged 6.33 runs per game in their last six and had a batting average of .279. The key to their offensive output has been their ability to generate home runs with a slugging percentage sitting at .475 in their last six resulting in ten home runs or 1.66 per game.

Right-handed pitcher Dean Kremer will be starting for the Orioles on Friday.

Dean Kremer:

  • has a 9-10 record with an ERA of 4.52 and 128 strikeouts in 27 appearances this season.
  • has given up 5 runs on 4 hits with 4 walks and a strikeout in 4.2 innings versus the Dodgers in his career.

Dodgers vs. Orioles pick

Spread pick for Dodgers vs. Orioles

 

  • Dodgers -1.5 (-110) (4 units)

The Dodgers are 5-2 against the run line in their last seven games against the Orioles. The Orioles had a 0-2 record against the run line as underdogs against the NL West at home in 2024. The Dodgers are going to need this win, especially after being swept by the Pirates. The Padres are closing the gap on the Dodgers and every win will count moving forward if the Dodgers wish to retain their position. Given they will leave nothing up to chance and their history, I have to side with them to cover their run line.

I am taking the Dodgers at -1.5.

Over/Under Pick for Dodgers vs. Orioles

  • Under 8.5 (-105 ) (4 units)

The Dodgers have an over/under record of 2-5-2 in their last nine games. The Orioles have an over/under record of 10-18 as underdogs at home this season. While the Orioles are exhibiting more offensive prowess as of late, I have to side with a lower scoring game as the Dodgers tend to play better when their pitching can shut down the opposition. This will lead to a one sided game that should not see many runs.

I am siding with the over at 8.5.

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