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Minnesota Twins vs. Los Angeles Angels Prediction and Picks - September 9, 2025

By: Sean Harper Updated 09/09/2025, 12:29 PM ET
Minnesota Twins vs Los Angeles Angels Prediction and Picks

The MLB is winding down the 2025 regular season with a matchup between the Minnesota Twins vs the Los Angeles Angels. Look inside for our late-season prediction and picks. The Minnesota Twins (64-80, 29-44 away) will face off against the Los Angeles Angels (67-77, 35-38 home) on September 10, 2025, at Angel Stadium in Anaheim, California. The game is scheduled for 3:07 PM local time, with weather conditions expected to be sunny and warm at 79°F. The Twins will send right-hander Taj Bradley (6-7, 4.92 ERA) to the mound, while the Angels counter with right-hander Jose Soriano (10-10, 4.07 ERA). The Twins lead the season series 4-0 after a dominant 12-3 win on Monday night.

When it comes to MLB picks, our MLB Predictions are stellar!

Twins Dominate Angels 12-3 Behind Lewis

The Minnesota Twins cruised to a 12-3 victory over the Los Angeles Angels at Angel Stadium, powered by Royce Lewis’ two home runs and four RBIs, along with a solo homer from James Outman. Simeon Woods Richardson earned the win with a steady five-inning performance, allowing three earned runs and striking out six, while the Twins’ offense capitalized on four Angels errors to extend their lead. With 12 hits and contributions from across the lineup, the Twins showcased their ability to dominate both offensively and defensively, improving to 64-80 on the season.

Injuries have plagued the Twins, with key players like Cory Lewis (SP), Anthony Misiewicz (RP), and Daniel Duarte (RP) on the injured list. Byron Buxton (CF) and Justin Topa (RP) are listed as day-to-day, which could impact their lineup and bullpen depth. Statistically, the Twins have struggled offensively, with a team batting average of .239 and an average of 4.2 runs per game. Their pitching staff has a team ERA of 4.56, ranking them in the bottom half of the league. Defensively, they average 0.6 errors per game, which has contributed to their struggles in close contests. Taj Bradley, the Twins’ probable starter, has had an up-and-down season with a 4.92 ERA and 1.31 WHIP over 126.1 innings. While he has shown flashes of potential, his inconsistency has been a concern, particularly against teams with power-heavy lineups like the Angels.

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Angels Struggle with Inconsistency Amid Injuries and Defensive Woes

The Los Angeles Angels have been inconsistent, going 2-4 in their last six games. After suffering back-to-back blowout losses to Oakland (17-4 and 10-4), they bounced back with a narrow 4-3 win followed by a 12-3 loss to the Twins in their most recent game. Jo Adell, who leads the team with 35 home runs and 94 RBIs, has been a key contributor, though he is currently listed as day-to-day with a minor injury. The Angels have also been without Nolan Schanuel (1B) and Jorge Soler (RF), both on the injured list, which has limited their offensive depth.

The Angels’ offense has been slightly more productive than the Twins, with a team batting average of .228 and an average of 4.3 runs per game. Their pitching staff, led by Jose Soriano, has a team ERA of 4.81, which ranks near the bottom of the league. Soriano has been a workhorse this season, pitching 163.2 innings with a 4.07 ERA and 148 strikeouts. Defensively, the Angels average 0.7 errors per game, which has occasionally cost them in tight games.

Angels vs. Twins Pick

Spread Pick for Angels vs. Twins

  • Los Angeles Angels -1.5 (4 Units)

The Twins have been more reliable against the run line as away underdogs, covering 66% of the time (31-16). However, they have struggled overall, covering just 46.9% of their games this season. The Angels, on the other hand, have been strong as home underdogs, covering 67.4% of the time (31-15). Both teams have been inconsistent against the spread, but the Angels’ home-field advantage and slightly better recent form give them an edge. The Angels are favored to win this matchup, and with Soriano on the mound, they have a solid chance to cover the run line. Go with Los Angeles!

Over/Under Pick for Angels vs. Twins

  • Over 8.5 (5 Units)

The Twins have gone under the total in 53.3% of their games as away underdogs, while the Angels have gone over in 54.7% of their games overall. Recent trends suggest that the Angels’ games tend to hit the over when playing at home, especially against teams with struggling pitching staffs like the Twins. Bet the over on total runs with confidence, as both teams have shown vulnerabilities in their pitching and defensive performances. Go OVER and Good Luck!

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