Arizona Diamondbacks vs Colorado Rockies Picks and Prediction for Thursday, September 24, 2026

On Thursday, the Arizona Diamondbacks visit the Colorado Rockies at Coors Field, with the opening pitch scheduled for 3:10 PM ET and the game televised on MLB.TV. Arizona is 83-74, 38-38 away and third in the NL West, 14 games behind Los Angeles. The Diamondbacks have won three straight, including Tuesday’s 7-2 victory over Colorado, and sit four games behind the final NL wild-card position. Colorado is 57-100, 32-47 at home and fifth in the NL West. The Rockies have lost two straight and have been eliminated from playoff contention. Let’s break down the matchup with our free MLB picks.

Arizona Diamondbacks Riding a Three-Game Winning Streak

Arizona has scored 20 runs during its three-game winning streak, beating the Yankees 5-3 and 8-4 before Tuesday’s 7-2 victory at Coors Field. Gabriel Moreno leads Arizona with a .306 average, .384 on-base percentage and .481 slugging percentage while adding 15 home runs and 77 RBI. Nolan Arenado has supplied the biggest power numbers with 28 homers and 79 RBI. Corbin Carroll has 22 home runs, 73 RBI and 21 stolen bases, while Ketel Marte has also hit 22 homers.

The Diamondbacks are batting .245 with 700 runs, 158 home runs, a .316 on-base percentage and .399 slugging percentage. Arizona ranks 15th in MLB in batting average, while its pitching staff ranks 12th with a 4.09 ERA. Diamondbacks pitchers have recorded a 1.27 WHIP and .247 opponent average across 1,399 innings. Arizona has also been one of baseball’s best defensive clubs, ranking second with 64 errors and a .989 fielding percentage.

Injuries: Tyler Locklear (out), Ryan Thompson (out), A.J. Puk (out), Andrew Saalfrank (out), Cristian Mena (out).

Colorado Rockies Trying to Reverse a Difficult Stretch

Colorado has lost four of its last five games, with the only victory coming 5-3 against Seattle. Hunter Goodman has been Colorado’s top power hitter with 39 home runs, 82 RBI and a .524 slugging percentage. TJ Rumfield is batting .298 with a .389 on-base percentage and 159 hits, while Jake McCarthy has a .295 average, 15 homers, 83 RBI and 31 stolen bases. Mickey Moniak has added 23 home runs and 65 RBI.

The Rockies are batting .253 with 729 runs, 171 home runs, a .323 on-base percentage and .415 slugging percentage. Colorado ranks fifth in MLB in batting average, but pitching has been a major issue. The Rockies rank 30th with a 5.58 ERA, 1.53 WHIP, and .288 opponent average while allowing 216 home runs. Colorado also ranks 24th defensively with 96 errors and a .983 fielding percentage. The Rockies are 17-36 in day games.

Injuries: Kris Bryant (out), Willi Castro (out), McCade Brown (out), Chase Dollander (out), Pierson Ohl (out).

Pitching Matchup

Arizona Diamondbacks - Eduardo Rodriguez

Eduardo Rodriguez is 15-7 with a 2.89 ERA and 1.23 WHIP across 183.2 innings. The left-hander has allowed 164 hits and 18 home runs while striking out 140 and walking 62. 

Colorado Rockies - Tanner Gordon

Tanner Gordon is 1-5 with a 6.01 ERA and 1.55 WHIP across 100.1 innings. The right-hander has surrendered 136 hits and 19 home runs while recording 84 strikeouts and only 20 walks. 

Arizona Diamondbacks vs Colorado Rockies Game Pick

• Arizona Diamondbacks

Arizona is the pick with a large starting-pitching advantage and much more at stake late in the season. Rodriguez owns a 2.89 ERA and 1.23 WHIP, while Gordon has posted a 6.01 ERA and allowed 136 hits in 100.1 innings. Arizona has also won three straight and scored seven runs in Tuesday’s series opener. Colorado can hit, but its pitching staff owns a 5.58 ERA and .288 opponent average. Those numbers create another favorable setup for the Diamondbacks at Coors Field.

Arizona Diamondbacks vs Colorado Rockies Over/Under Pick

• Over

The play is over with Coors Field pairing two offenses capable of producing runs and a Colorado staff that has struggled throughout the season. The Rockies are batting .253 with a .415 slugging percentage and 729 runs, while Arizona has scored 20 times during its three-game winning streak. Gordon’s 6.01 ERA and 1.55 WHIP add another major scoring factor. Rodriguez can limit Colorado, but the Diamondbacks have a favorable matchup against a Rockies staff that has allowed a .288 opponent average and 216 home runs.