Arizona Diamondbacks vs San Francisco Giants Picks and Prediction for Thursday, August 27, 2026

The Arizona Diamondbacks visit the San Francisco Giants at Oracle Park on Thursday, with first pitch scheduled for 9:45 PM ET. Arizona is 70-63, third in the NL West and one game behind San Diego for the final National League Wild Card spot. The Diamondbacks are 3-2 over their last five after beating the Cubs 5-4 on Tuesday. San Francisco is 54-78, fourth in the NL West and 16.5 games behind the final Wild Card position. The Giants have won two straight, including a 3-1 victory over Cincinnati on Tuesday. Arizona has dominated the season series, winning eight of nine meetings. Build your bankroll Thursday with our free MLB picks.

Arizona Diamondbacks Fighting for a Wild Card Spot

Arizona enters the series with plenty at stake in the National League playoff race. The Diamondbacks have alternated wins and losses across their last five games, beating Cincinnati 9-0 and 5-3 before splitting their first two games against Chicago. Arizona has been close to even away from home at 31-34 and has scored 603 runs while allowing 600 through 133 games.

The Diamondbacks are batting .244 with a .317 on-base percentage and .398 slugging percentage. Gabriel Moreno leads Arizona with a .303 batting average and .382 on-base percentage, while Nolan Arenado has a team-high 21 home runs. Ketel Marte also has 21 homers and leads the club with 67 RBI. Corbin Carroll has supplied another important part of the offense, recording 121 hits, 18 home runs, 58 RBI and 20 stolen bases. Arizona’s pitching staff ranks 18th in MLB with a 4.21 ERA and 1.29 WHIP.

Injuries: Jordan Lawlar is day-to-day, Lourdes Gurriel Jr. and Tommy Troy are on the 10-Day IL, Ryan Thompson is on the 15-Day IL and Blake Walston is on the 60-Day IL.

San Francisco Giants Look for Third Straight Win

San Francisco has responded to a three-game losing streak by winning its last two contests. The Giants closed their Boston series with three consecutive defeats before returning home and shutting out Cincinnati 5-0 on Monday. San Francisco followed with a 3-1 win Tuesday. The Giants are 31-33 at Oracle Park but have struggled overall, sitting 24 games below .500 with 30 games remaining on the schedule.

San Francisco ranks 10th in MLB with a .247 batting average and has produced 531 runs, 146 home runs, a .306 on-base percentage and .405 slugging percentage. Luis Arraez leads the Giants with a .324 average, .360 on-base percentage and 136 hits. Rafael Devers provides the primary power threat with 28 home runs and 74 RBI, while Willy Adames and Casey Schmitt have each hit 21 homers. The Giants rank 23rd in pitching with a 4.30 ERA and 1.35 WHIP.

Injuries: Jesus Rodriguez and Marcelo Mayer are on the 10-Day IL, Matt Gage is on the 60-Day IL, Adrian Houser is day-to-day and Bryce Eldridge is on bereavement leave.

Pitching Matchup

Arizona Diamondbacks - Undecided

Arizona had not yet announced its starting pitcher at the time this preview was written.

San Francisco Giants - Logan Webb

Webb is 8-8 with a 3.75 ERA and 1.11 WHIP across 141.2 innings. The right-hander has allowed 122 hits, 35 walks and 10 home runs while striking out 112. Webb has limited baserunners throughout his workload, allowing fewer hits than innings pitched while keeping his walk total low. His 1.11 WHIP is considerably better than San Francisco’s 1.35 team mark.

Arizona Diamondbacks vs San Francisco Giants Game Pick

• Arizona Diamondbacks

Arizona has controlled this matchup throughout the season, winning eight of nine games against San Francisco, and the Diamondbacks enter Thursday only one game outside the final National League Wild Card spot. Arizona has also scored 72 more runs than San Francisco this season and owns the better overall record at 70-63. The Giants have won two straight, but their 54-78 record and 23-45 road mark highlight their season-long problems. Arizona’s deeper lineup and dominant head-to-head results make the Diamondbacks the pick Thursday night.

Arizona Diamondbacks vs San Francisco Giants Over/Under Pick

• Under

Recent scoring results point toward a lower-scoring game at Oracle Park. San Francisco has allowed only one run across its last two games, beating Cincinnati 5-0 and 3-1, while four of the Giants’ last five contests have finished with eight combined runs or fewer. Arizona has also been held scoreless once during its last five games. San Francisco averages just over four runs per game this season, while Arizona sits at roughly 4.5. Those scoring numbers and the Giants’ recent results support the under Thursday.