Arizona Diamondbacks vs San Francisco Giants Prediction and Picks - Monday, September 8, 2025
An NL West matchup goes down on Monday, September 8, as the Arizona Diamondbacks take on the San Francisco Giants at 9:45 p.m. ET, so continue reading for our Diamondbacks vs Giants prediction. This is written before Sunday's game has ended.
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Diamondbacks Take Series Against Red Sox
Arizona has won the first two games against the Red Sox to take the series as the Diamondbacks look for the sweep on Sunday. Arizona enters play on Sunday with a record of 72-71. The Diamondbacks are hitting .250, which ranks 13th, while on the road are hitting .245. Against the Giants, Arizona is hitting .268.
The Diamondbacks are set to start right-hander Nabil Crismatt, who's 2-0 with a 2.14 ERA in 4 appearances, including three starts. Last time out, he went 6.1 innings, allowing two runs against the Rangers. He's 2-0 with a 5.24 ERA in his career against the Giants in 15 appearances. Arizona has a team ERA of 4.45, which ranks 23rd.
Giants Chasing Wild Card Spot
San Francisco enters play on Sunday with a record of 72-70 and is four games back of a Wild Card spot. The Giants have split the first two games against the Cardinals. San Francisco is set to start right-hander Logan Webb, who's 13-9 with a 3.17 ERA in 29 starts this season. Last time out, he went five innings, allowing two runs against the Rockies. He's 6-4 with a 2.46 ERA in his career against the Diamondbacks. San Francisco has a team ERA of 3.76, which ranks fifth.
The Giants are hitting .239, which ranks 24th, while at home, they are hitting .240. Against the Diamondbacks, San Francisco is hitting .272, while in the month of September, they are hitting .332.
Diamondbacks vs Giants Pick
Spread Pick for Diamondbacks vs. Giants
- Giants ML (5 units)
San Francisco is starting Webb, who will be the difference here, as this is a great spot for the Giants to get the win. The Giants' offense is also hot as of late, as San Francisco should be able to continue their success against Crismatt, who has been hit hard by the Giants. Expect Webb to go 6-7 innings, allowing only a couple of runs to cruise to a big win in the series opener on Monday.
Take the Giants ML.
Over/Under Pick for Diamondbacks vs Giants
- Under (4 Units)
With Webb on the mound, the under is a great spot here as San Francisco's pitching staff is one of the best in the majors and will limit the offense. This season, the Giants are 68-66-8 in hitting the under, while at home are 38-28-3 in hitting the under. Arizona, meanwhile, is 67-67-9 in hitting the under, while on the road they are 34-33-5. Look for those trends to continue as the under is a great spot.
Take the under.