Arizona Diamondbacks vs St. Louis Cardinals Picks and Prediction for Thursday June 25 2026

By: Kim Smith Published 06/25/2026, 01:00 AM ET
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The New York Yankees travel to face the Boston Red Sox at Fenway Park in Boston, Massachusetts, on Thursday, June 25, 2026. First pitch is scheduled for 7:10 PM with coverage available on MLB.TV and MLB Network. At the time of this writing the odds were not released. Be sure to check out our free MLB picks.

Starting Pitchers Headline the Fenway Park Matchup

The Yankees are expected to send Cam Schlittler to the mound. He enters the game with an impressive 8-3 record, a 1.71 ERA, and a 0.89 WHIP across 95.0 innings. He has allowed 67 hits while striking out 109 batters, walking only 18, and surrendering five home runs. Boston is expected to counter with Connelly Early, who owns a 6-5 record with a 3.64 ERA and a 1.27 WHIP over 81.2 innings. He has allowed 73 hits while recording 79 strikeouts, issuing 31 walks, and giving up 14 home runs. Based strictly on the numbers provided, New York enters with a notable advantage in the starting pitching matchup.

Yankees Seeking Another Road Victory

New York enters Thursday's contest with a 47-31 overall record and a strong 25-16 record away from home. The Yankees have gone 2-3 over their last five games, recently defeating Detroit while also suffering losses to Detroit and Cincinnati. Their most recent victory was a narrow 4-3 road win.

The Yankees are batting .245 as a team with 396 runs scored, 636 hits, and 116 home runs. They own a .330 on-base percentage and a .437 slugging percentage. The pitching staff has been one of the best units in this matchup, posting a 3.37 ERA and a 1.18 WHIP while limiting opponents to a .226 batting average. New York has also recorded 678 strikeouts and holds a 30-20 record in night games.

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The biggest strength for New York is its overall balance. The Yankees lead this matchup in runs scored, home runs, on-base percentage, slugging percentage, ERA, WHIP, and opponent batting average. Those advantages have helped them maintain one of the strongest records among the teams featured here.

Red Sox Looking to Defend Home Field

Boston enters the matchup with a 32-45 overall record and a 12-25 record at home. The Red Sox have won three of their last five games, earning victories over Colorado and Seattle while dropping contests against Colorado and Seattle during that same stretch.

The Red Sox are batting .243 with 301 runs scored, 628 hits, and 65 home runs. Boston owns a .312 on-base percentage and a .381 slugging percentage. On the mound, the Red Sox have compiled a 3.82 ERA and a 1.26 WHIP while allowing opponents to hit .244. The staff has recorded 647 strikeouts and issued 228 walks. Boston also owns a 21-25 record in night games.

The primary strength for Boston is its pitching staff. While the Red Sox trail New York in several offensive categories, their 3.82 ERA is solid and gives them a chance to stay competitive. Keeping games close has been important for a club that has not generated offense at the same level as the Yankees.

New York Yankees vs Boston Red Sox Picks and Prediction

New York Yankees vs Boston Red Sox Pick

  • Pick: New York Yankees Moneyline

The Yankees enter this game with the better overall record, the stronger road record, and the advantage in the starting pitching matchup. They also hold clear edges in offensive production and team pitching statistics. Those factors make New York the preferred side in this contest.

New York Yankees vs Boston Red Sox Total Pick

  • Take the under if the total is set at 8.5.

I would lean toward the under if the total is set at 8.5 because both teams bring respectable pitching numbers into the matchup, and the Yankees' starter has been particularly dominant this season. With New York owning a team ERA of 3.37 and Boston carrying a 3.82 ERA, runs may be more difficult to find than expected.

Final Score Prediction: New York Yankees 5 – Boston Red Sox 3

This prediction was written before the completion of game play on Wednesday.

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