Athletics vs Chicago White Sox Picks and Prediction for Friday, July 10, 2026

By: Kim Smith Published 07/10/2026, 01:00 AM ET
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The Athletics travel to Rate Field in Chicago, Illinois, to face the Chicago White Sox on Friday, July 10, 2026. First pitch is scheduled for 7:40 PM ET, with coverage available on MLB.TV. The Athletics enter the matchup with a 41-51 overall record and a 22-23 mark on the road, while the White Sox are 47-44 overall and an impressive 28-16 at home. At the time of this writing the odds were not released. ESPN Analytics gives the White Sox a 60.7% chance to win compared to 39.3% for the Athletics. Be sure to check out our ⁠free MLB Picks.

Starting Pitchers

The Athletics are expected to start Aaron Civale, who enters Friday’s game with a 5-6 record, a 5.10 ERA, and a 1.58 WHIP over 72.1 innings. He has allowed 92 hits while striking out 54 batters, walking 22, and giving up 16 home runs. Chicago is expected to counter with Sean Burke, who owns a 5-4 record with a 3.56 ERA and a 1.22 WHIP across 98.2 innings. Burke has surrendered 87 hits while recording 106 strikeouts, issuing 33 walks, and allowing 12 home runs. Based strictly on the numbers provided, Burke enters with advantages in ERA, WHIP, innings pitched, and strikeouts.

Athletics Search for a Turnaround

The Athletics head into Friday night’s contest with a 41-51 overall record and a 22-23 mark on the road. They have struggled over the past week, dropping each of their last five games. The Athletics recently lost to Detroit twice after being swept through three games by Miami. That losing streak has made this an important opportunity to reset as they begin a new series.

Offensively, the Athletics are batting .247 with 419 runs, 776 hits, and 115 home runs. They have posted a .325 on-base percentage and a .407 slugging percentage. Their pitching staff owns a 5.13 ERA with a 1.47 WHIP while allowing opponents to hit .266. The Athletics have also drawn 360 walks, struck out 775 batters, and hold a 12-18 record in day games.

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The biggest positive for the Athletics has been their offensive power. They have hit 115 home runs and own the better batting average than Chicago. However, their pitching numbers have made it difficult to consistently capitalize on that offensive production, as they carry the higher ERA, higher WHIP, and higher opponent batting average into this matchup.

Chicago Hopes to Protect Its Home Field

The White Sox enter the series with a 47-44 overall record and an outstanding 28-16 home record. Chicago has gone 2-3 over its last five games, recently losing twice to Boston after picking up two wins against Cleveland and another extra-inning loss in that same series. Despite the recent setbacks, the White Sox have been difficult to beat at home throughout the season.

Chicago is hitting .239 with 429 runs, 728 hits, and 125 home runs. The White Sox own a .319 on-base percentage and a .411 slugging percentage. Their pitching staff has produced a 4.25 ERA with a 1.34 WHIP while limiting opponents to a .241 batting average. Chicago has also issued 353 walks while recording 771 strikeouts, and the club owns an 18-22 record in day games.

The White Sox have combined power with stronger pitching. Chicago has hit more home runs than the Athletics while also posting better numbers in ERA, WHIP, and opponent batting average. That balanced profile, along with the strong home record, gives the White Sox a clear statistical advantage entering Friday night’s game.

Athletics vs Chicago White Sox Picks and Prediction

Athletics vs Chicago White Sox Pick

  • Pick: Chicago White Sox Moneyline

The White Sox are the stronger choice based on the information provided. Chicago owns the better overall record, an excellent 28-16 home mark, and the higher ESPN Matchup Predictor percentage. The projected starting pitching matchup also favors the White Sox, with Sean Burke holding advantages in ERA, WHIP, and strikeouts. Those factors make Chicago the preferred side.

Athletics vs Chicago White Sox Total Pick

  • Pick: Over 8.5

I’m taking the over if the total is set at 8.5. The Athletics have allowed a 5.13 team ERA this season, while both teams have surpassed 100 home runs. Chicago has hit 125 home runs and the Athletics have hit 115, so I expect enough offense for this matchup to finish above the total.

Final Score Prediction: Chicago White Sox 6 – Athletics 4

This prediction was written before the completion of game play on Thursday.

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