Athletics vs. Los Angeles Angels Picks and Prediction, Saturday, September 6, 2025
An AL West matchup goes down on Saturday, September 6 at 9:38 p.m. ET as the Athletics are on the road to play the Los Angeles Angels, so continue reading for our Athletics vs Angels prediction. This is written before Friday's game has ended.
When it comes to baseball picks, our MLB Predictions are stellar.
Athletics Drop Series to Cardinals
The Athletics enter play on Friday with a record of 64-77, which is dead last in the AL West. The A's lost the final two games of their three-game series to the St. Louis Cardinals to lose the series. This season, the A's are hitting .253, which ranks fifth. While on the road, the Athletics hit .247. Against left-handers, they hit .258. Against Kikuchi, Thomas is 2-for-2 with a homer, Kurtz hits .200 in 5 ABs, Langeliers hits .167 with a homer in 6 ABs, and Rooker hits .111 in 9 ABs.
The Athletics are set to start right-hander J.T. Ginn, who's 2-6 with a 5.17 ERA in 19 games, including 12 starts. Last time out, he went 6 innings, allowing 5 runs against the Rangers. He's 0-1 with a 9.00 ERA in his career against the Angels, while they have a team ERA of 4.81, which ranks 28th.
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Angels Starting Kikuchi
Los Angeles enters play on Friday with a record of 66-74 and is coming off a series win over the Kansas City Royals on the road. The Angels will be starting left-hander Yusei Kikuchi, who's 6-10 with a 3.83 ERA in 29 starts this season. Kikuchi is 3-4 with a 3.41 ERA in his career against the Athletics, while last time out, he went 5.2 innings, allowing 5 runs against the Astros. Los Angeles has a team ERA of 4.70, which ranks 26th.
The Angels are hitting .228, which ranks 29th, while at home, they are hitting .228. Against the Athletics, Los Angeles is hitting .266. Against Ginn, Neto, O'Hoppe, and Rengifo is 1-for-2; Ward is 1-for-2 with a homer. Adell and Lugo are 0-for-2, and Moncada is 0-for-1.
Athletics vs. Angels Pick
Spread Pick for Athletics vs. Angels
- Angels ML (5 units)
The Athletics and the Angels have both struggled this season, but this is a great spot for the Angels to get the win here at home. Kikuchi has pitched well enough that he will limit the Athletics offense, while Ginn has been hit hard in his career against the Angels, and that should continue here. Los Angeles' offense will be able to score plenty of runs here to cruise to a big win at home, backed by a good enough performance by Kikuchi.
Over/Under Pick for Athletics vs. Angels
- Over (5 units)
The over is also a good spot here, as the pitching matchup should lead to plenty of runs. Ginn has been hit hard this season and in his career against the Angels. Meanwhile, in the 10 games these two teams have played this season, the games have averaged 11.2 runs, which is a good sign for the under. The Athletics are 69-62-10 in hitting the over, while the Angels are 73-61-6 in hitting the over, so look for those trends to continue here.
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