Athletics vs San Francisco Giants Picks and Prediction for Wednesday June 24 2026

By: Kim Smith Published 06/24/2026, 01:30 AM ET
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The Athletics and San Francisco Giants meet on Wednesday, June 24, 2026, at Oracle Park in San Francisco, California. First pitch is scheduled for 9:45 PM ET, with coverage available on MLB.TV. At the time of this writing the odds were not released. Be sure to check out our free MLB picks.

The Athletics are expected to start Gage Jump in this matchup. Jump enters with a 3-1 record, a 2.37 ERA, and a 0.99 WHIP across 30.1 innings. He has allowed 21 hits, struck out 26 batters, walked nine, and has not allowed a home run. San Francisco is scheduled to counter with Tyler Mahle, who comes into the game with a 1-7 record, a 6.04 ERA, and a 1.54 WHIP over 56.2 innings. He has allowed 63 hits, recorded 57 strikeouts, issued 24 walks, and surrendered 11 home runs.

Athletics Looking to Finish the Road Trip Strong

The Athletics enter this contest with a 38-40 overall record and a 20-17 road record. They have gone 2-3 over their last five games. The Athletics recently defeated the Angels twice while suffering losses to the Angels twice and Pittsburgh.

The Athletics are batting .250 as a team with 364 runs scored, 667 hits, and 105 home runs. They own a .329 on-base percentage and a .420 slugging percentage. On the pitching side, they have posted a 5.00 ERA and a 1.45 WHIP while recording 651 strikeouts. Opponents are batting .263 against them. The Athletics are also 27-24 in night games.

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The biggest strength for the Athletics has been their offensive production. They have scored more runs than San Francisco, hit significantly more home runs, and own advantages in on-base percentage and slugging percentage. Those offensive numbers have helped offset some struggles on the pitching side throughout the season.

Giants Hoping to Reverse Recent Struggles

The Giants come into this game with a 31-46 overall record and a 14-20 home record. San Francisco has gone 2-3 over its last five games. The Giants recently defeated Atlanta twice but suffered losses to Miami three consecutive times during their most recent series.

San Francisco is hitting .257 as a team with 317 runs scored, 684 hits, and 81 home runs. The Giants have produced a .309 on-base percentage and a .419 slugging percentage. Their pitching staff owns a 4.46 ERA and a 1.39 WHIP while recording 608 strikeouts. Opponents are batting .252 against San Francisco. The Giants are 16-30 in night games.

The strength of San Francisco has been its ability to consistently put the ball in play. The Giants hold advantages in batting average and total hits, and they have also posted a better ERA, WHIP, and opponent batting average than the Athletics. However, their overall record and night-game record have made it difficult to turn those advantages into consistent success.

Athletics vs San Francisco Giants Picks and Prediction

Athletics vs San Francisco Giants Pick

  • Pick: Athletics Moneyline

This matchup appears very close according to the matchup predictor, but the Athletics get the edge. They have the better overall record, stronger road record, and a substantial advantage in home run production. The projected starting pitching matchup also strongly favors the Athletics, as their starter enters with a significantly lower ERA and WHIP. Those factors make the Athletics the preferred side.

Athletics vs San Francisco Giants Total Pick

  • Take the over if the total is set at 8.

I would lean toward the over if the number is set at 8. The Athletics have hit 105 home runs and scored 364 runs this season, while San Francisco's projected starter enters with a 6.04 ERA and has allowed 11 home runs. The Athletics also own a 5.00 team ERA, which creates opportunities for the Giants to contribute offensively. Both teams have enough offensive production to push this game over the number.

Final Score Prediction: Athletics 6 – San Francisco Giants 4

This prediction was written before the completion of game play on Tuesday.

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