Atlanta Braves vs San Diego Padres Picks and Prediction for Monday June 22 2026

The Atlanta Braves and San Diego Padres meet at Petco Park in San Diego, California on Monday, June 22, 2026, with first pitch scheduled for 10:00 PM ET. The game will be televised on ESPN. At the time of this writing the odds were not released. Be sure to check out our free MLB picks.

Starting Pitchers Featured in San Diego

Atlanta is expected to start Grant Holmes in this matchup. Holmes enters with a 4-3 record, a 4.33 ERA, and a 1.40 WHIP across 68.2 innings. He has allowed 64 hits while striking out 61 batters, issuing 32 walks, and surrendering 13 home runs.

San Diego is expected to counter with Michael King. King comes into the game with a 4-6 record, a 3.60 ERA, and a 1.19 WHIP over 85.0 innings. He has allowed 66 hits while recording 73 strikeouts, issuing 35 walks, and giving up 10 home runs.

Atlanta Brings One of Baseball's Best Records West

The Braves enter Monday's contest with a 48-27 overall record and a strong 24-14 mark on the road. Atlanta has won two of its last five games, recently defeating Milwaukee twice. The Braves also dropped three games during that stretch, losing twice to San Francisco and once to New York. Despite those recent setbacks, Atlanta continues to own one of the strongest records in baseball.

Atlanta has been productive throughout the season, posting a .253 team batting average with 373 runs scored, 645 hits, and 100 home runs. The Braves own a .318 on-base percentage and a .422 slugging percentage. Their pitching staff has been equally impressive, producing a 3.34 ERA and a 1.19 WHIP while holding opponents to a .224 batting average. Atlanta pitchers have recorded 647 strikeouts and issued 244 walks.

The Braves' greatest strength is their overall balance. Atlanta owns advantages over San Diego in batting average, runs scored, hits, home runs, on-base percentage, slugging percentage, ERA, WHIP, strikeouts, and opponent batting average. Those numbers explain why the Braves have maintained such a strong record through this point of the season.

Padres Return Home Seeking Another Quality Win

The Padres enter this matchup with a 39-36 overall record and a 19-19 record at home. San Diego has won two of its last five games, recently defeating Texas and St. Louis. The Padres also suffered losses to Texas and St. Louis twice during that stretch. Their most recent game was a 6-4 extra-inning victory over Texas.

San Diego owns a .219 batting average with 293 runs scored, 538 hits, and 78 home runs. The Padres have posted a .292 on-base percentage and a .364 slugging percentage. On the pitching side, they carry a 3.90 ERA and a 1.30 WHIP while allowing opponents to hit .242. San Diego pitchers have recorded 623 strikeouts and issued 263 walks.

The strength of the Padres has been their pitching staff. While the offense has lagged behind Atlanta in nearly every category, San Diego has remained competitive because of a pitching staff that owns a sub-4.00 ERA and has limited opposing hitters to a .242 batting average.

Atlanta Braves vs San Diego Padres Picks and Prediction

Atlanta Braves vs San Diego Padres Pick

• Pick: Atlanta Braves Moneyline

Atlanta enters this matchup with the better overall record, stronger road record, and superior numbers across most offensive and pitching categories. The Braves also have a slight edge in overall pitching performance despite San Diego's expected starter carrying solid numbers. With advantages in runs scored, home runs, batting average, ERA, and WHIP, Atlanta is the side I prefer.

Atlanta Braves vs San Diego Padres Total Pick

• Pick: Take the under if the total is set at 8.0

I would lean toward the under if the total is set at 8.0. San Diego averages fewer runs than Atlanta and owns a .219 batting average as a team. Both clubs also bring solid pitching numbers into this contest, with Atlanta carrying a 3.34 ERA and San Diego posting a 3.90 ERA. Those factors point toward a lower-scoring matchup.

Final Score Prediction: Atlanta Braves 4 – San Diego Padres 3

This prediction was written before the completion of game play on Sunday.