Boston Red Sox vs. Toronto Blue Jays Pick and Prediction, Thursday, September 25, 2025
On Thursday afternoon, the Boston Red Sox and Toronto Blue Jays meet in the final game of a three-game series at Rogers Centre, and we will set you up with a Red Sox vs. Jays prediction to go along with free picks. Brayan Bello will pitch for the Red Sox while Shane Bieber throws for the Jays. Read on for a prediction on the score and a game breakdown. Need a hot take on the MLB Season? Check out our Free MLB Picks and cash in.
Red Sox Holding Steady
Entering action Wednesday afternoon, the Boston Red Sox are slotted into the second wild card spot in the American League, with a one-game lead on Houston and Detroit. Brayan Bello will toe the rubber in the final game of this series with Toronto.
- He was charged with the loss last Thursday against the Athletics, allowing four runs (three earned) on five hits and two walks in four innings. He struck out three.
- It was the first time Bello was unable to fire at least five innings since way back on May 28, and the 70 pitches were his second-lowest total of the season.
- The month of September has not been kind so far for the right-hander, who has a 5.85 ERA, 1.45 WHIP, and 13:9 K:BB across his last 20 innings.
- Bello will try to develop some consistency and right the ship in what may be his final appearance of the regular season here in Toronto, where he'll bring a career-best 3.34 ERA and 1.24 WHIP to go with a 121:56 K:BB over 161.2 frames. But he has not been sharp lately, and this is a huge game, so the leash may be short.
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Bieber Toes the Rubber in Finale
Shane Bieber will take the mound in the final game of this divisional series with the Sox. He gave up two runs on four hits and one walk over 6.1 innings to take the loss Saturday against Kansas City. He struck out four in another strong effort.
- The right-hander picked up his second consecutive quality start, as both runs he yielded came on back-to-back solo homers by Bobby Witt and Vinnie Pasquantino in the fourth inning.
- The one-time Cy Young Award winner has been excellent in his 35.1 total innings, pitching to a 3.57 ERA, 0.96 WHIP, and 34:5 K:BB. Bieber is slated to make his final start of the season at home against the Red Sox here.
- The Blue Jays had hoped to shuffle their rotation in preparation for the playoffs, but they are not out of the woods yet, as the American League is tightening up.
Entering play Wednesday, the Blue Jays hold a one-game lead on the New York Yankees for first place in the AL East. They have been dominant at Rogers Centre, recording a 50-26 mark. But the Yankees are right on their tail.
Red Sox vs. Blue Jays Game Pick
Money Line Pick for Red Sox vs. Blue Jays
- Toronto Blue Jays -1.5 (4 units)
Shane Bieber has shown flashes of his Cy Young form in 35+ innings for the Blue Jays. He has a 3.57 ERA, 0.96 WHIP, and 34:5 K: BB and will take the mound in this critical game. The Red Sox sit in the second AL wild-card spot, one game up on the Detroit Tigers and two games over the Houston Astros, making each of their remaining games just as crucial as they are for Toronto. The Blue Jays have clinched at least a wild-card berth, and I like them here in this game against Bello, who has been average at best lately, posting a 5.85 ERA over his last 20 frames. Take Toronto by two.
OVER/UNDER PICK for Red Sox vs. Blue Jays
- UNDER (4 units)
Toronto is clinging to the American League East title and holds a one-game lead on the Yankees entering play Wednesday. The Blue Jays had hoped to shuffle their rotation in preparation for the playoffs, but they are not out of the woods yet, as the American League is tightening up. Bello and Bieber understand the magnitude of this game, so I expect a strong effort from both pitchers and a short leash if they struggle. The total has gone under in four of Toronto’s last six games facing AL foes. Take the under.
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