Chicago Cubs vs New York Mets Picks and Prediction for Monday June 22 2026

The Chicago Cubs and New York Mets meet at Citi Field in Queens, New York on Monday, June 22, 2026, with first pitch scheduled for 7:10 PM ET. The game will be televised on MLB.TV. At the time of this writing the odds were not released. Be sure to check out our free MLB picks.

Starting Pitchers Take the Spotlight

Chicago is expected to start Edward Cabrera in this matchup. Cabrera enters with a 4-4 record, a 5.21 ERA, and a 1.40 WHIP across 67.1 innings. He has allowed 69 hits while striking out 61 batters, issuing 25 walks, and surrendering 14 home runs.

New York is expected to counter with Kodai Senga. Senga has struggled this season, posting a 0-5 record with a 9.00 ERA and a 1.88 WHIP over 24.0 innings. He has allowed 28 hits while recording 28 strikeouts, issuing 17 walks, and giving up 7 home runs.

Chicago Hopes to Continue Its Winning Form

The Cubs enter this contest with a 40-37 overall record and a 17-20 mark on the road. Chicago has won three of its last five games, recently defeating Toronto and Colorado twice. The Cubs also recently lost to Toronto and Colorado during that stretch but have still managed to post a winning record over their last five contests.

Chicago owns a .244 team batting average with 366 runs scored, 639 hits, and 90 home runs. The Cubs have produced a .337 on-base percentage and a .401 slugging percentage. On the mound, Chicago carries a 4.28 ERA and a 1.24 WHIP while allowing opponents to hit .240. The pitching staff has recorded 602 strikeouts and issued 231 walks.

The biggest strength for Chicago is its ability to consistently reach base. The Cubs own a .337 on-base percentage, which is significantly better than New York's mark. They have also scored more runs, collected more hits, and hit more home runs, giving them an offensive advantage entering this matchup.

New York Looking to Gain Ground at Home

The Mets enter Monday with a 34-42 overall record and an 18-18 record at home. New York has won two of its last five games, recently defeating Philadelphia and Cincinnati. The Mets also suffered losses to Philadelphia once and Cincinnati twice during that stretch, including a 15-3 defeat in their most recent game.

New York has posted a .233 batting average with 309 runs scored, 592 hits, and 81 home runs. The Mets own a .298 on-base percentage and a .373 slugging percentage. Their pitching staff has produced a 4.07 ERA and a 1.28 WHIP while allowing opponents to hit .233. New York pitchers have recorded 688 strikeouts and issued 270 walks.

One area working in New York's favor is the pitching staff's ability to generate strikeouts. The Mets have recorded 688 strikeouts this season, well ahead of Chicago's total. They also hold a slight edge in ERA and opponent batting average, helping keep them competitive despite offensive struggles.

Chicago Cubs vs New York Mets Picks and Prediction

Chicago Cubs vs New York Mets Pick

• Pick: Chicago Cubs Moneyline

Chicago enters this matchup with the better overall record and an advantage in ESPN's matchup predictor. The Cubs also lead the Mets in batting average, runs scored, hits, home runs, on-base percentage, and slugging percentage. While New York has some advantages on the pitching side, Chicago's stronger offensive profile and better recent results make the Cubs the preferred selection.

Chicago Cubs vs New York Mets Total Pick

• Pick: Take the over if the total is set at 8.5

I would lean toward the over if the total is set at 8.5. Chicago has scored 366 runs and hit 90 home runs this season, while New York has allowed several high-scoring games recently. Both starting pitchers enter with ERAs above 5.00, including one at 9.00, which suggests opportunities for offense from both lineups.

Final Score Prediction: Chicago Cubs 6 – New York Mets 4

This prediction was written before the completion of game play on Sunday.