Chicago White Sox vs Detroit Tigers Picks and Prediction for Sunday, August 16, 2026

The Chicago White Sox visit the Detroit Tigers at Comerica Park in Detroit, Michigan, on Sunday, August 16, 2026. First pitch is scheduled for 1:40 PM ET, with MLB.TV providing television coverage. Chicago enters the matchup at 63-58 overall and 26-34 on the road, while Detroit is 60-62 overall and 32-29 at home. At the time of this writing, the odds were not released. Before making your selections for Sunday’s matchup, check out our free MLB picks for more baseball predictions and analysis.

Starting Pitchers

Sean Burke is scheduled to start for Chicago and enters at 7-6 with a 2.99 ERA and 1.08 WHIP across 135.2 innings. He has allowed 108 hits and 15 home runs while recording 152 strikeouts against 39 walks. Detroit counters with Drew Anderson, who is 4-4 with a 3.91 ERA and 1.30 WHIP through 71.1 innings. He has surrendered 66 hits and 10 home runs while striking out 82 and walking 27. Chicago owns the statistical advantage in the starting matchup, with the lower ERA and WHIP along with strong strikeout production over a considerably larger workload.

Chicago Brings the Stronger Starting Matchup

Chicago enters Sunday at 63-58 overall and sits atop the AL Central, although its 26-34 road record has been a weakness. The White Sox are 3-2 over their last five completed games, including a 9-5 road victory over Detroit on Friday. They also defeated Cincinnati 5-0 and Cleveland 5-3, while their two losses to Cincinnati came by scores of 9-8 and 5-4 in 10 innings.

The White Sox are batting .239 with a .318 on-base percentage and .410 slugging percentage. Chicago has scored 583 runs on 973 hits while hitting 161 home runs. Its pitching staff carries a 4.11 ERA and 1.30 WHIP while holding opponents to a .238 batting average. Chicago pitching has recorded 1,024 strikeouts while issuing 438 walks.

Chicago's biggest advantage is the combination of power and its scheduled starter. The White Sox have hit 161 home runs compared with Detroit's 148 and have scored 26 more runs. Their primary concern is overall run prevention, as the 4.11 team ERA and 1.30 WHIP trail Detroit's marks by a noticeable margin. Chicago will need its starting pitching advantage to help compensate for those season-long differences.

Detroit Looks to Answer at Comerica Park

Detroit enters the matchup at 60-62 overall and 32-29 at home. The Tigers have gone 3-2 over their last five completed games despite losing 9-5 to Chicago on Friday. Their three victories during that stretch came by scores of 3-0 and 6-4 against Cleveland and 3-1 in 10 innings at San Francisco. Their other loss was a 6-4 decision against Cleveland.

The Tigers are batting .243 this season with a .319 on-base percentage and .408 slugging percentage. Detroit has scored 557 runs on 1,001 hits while producing 148 home runs. The pitching staff has been the team's statistical strength, posting a 3.52 ERA and 1.21 WHIP while limiting opponents to a .231 batting average. Detroit has recorded 1,000 strikeouts against 373 walks.

Detroit's biggest advantage comes from its season-long pitching performance and home record. The Tigers have the better team ERA, WHIP, and opponent batting average while issuing 65 fewer walks than Chicago. Detroit also owns a winning record at Comerica Park, but Sunday's scheduled starting matchup presents a challenge against a Chicago starter carrying a 2.99 ERA and 1.08 WHIP.

Chicago White Sox vs Detroit Tigers Picks and Prediction

Pick: Chicago White Sox Moneyline

Chicago gets the nod in a matchup between two teams separated by only a few games in the standings. The White Sox are 3-2 over their last five completed games and have the stronger scheduled starting matchup, with their starter carrying a 2.99 ERA and 1.08 WHIP compared with a 3.91 ERA and 1.30 WHIP for Detroit's starter. Chicago also holds season advantages in runs scored, home runs, and slugging percentage, giving the White Sox enough offensive support to back the starting-pitching edge.

Pick: Under 8.5

Take the under if the total is set at 8.5. Chicago's scheduled starter has a 2.99 ERA and 1.08 WHIP, while Detroit owns a strong 3.52 team ERA and 1.21 WHIP. Both teams have shown the ability to play lower-scoring games recently, and Sunday's starting matchup is stronger than the 9-5 score from Friday might suggest. At 8.5, the under is the preferred play.

Preview was completed prior to game play on Saturday.