Cincinnati Reds vs. Milwaukee Brewers Picks and Prediction for Saturday, September 28, 2025
Use Code SSWC In the final game of the 2025 regular season, the Cincinnati Reds are facing off against the Milwaukee Brewers inside American Family Field on Sunday afternoon in our Reds vs. Brewers prediction. The Reds were able to record a 7-4 road win on Saturday. The Reds are third in the NL Central with an 83-78 record and are sending right-hander Brady Singer to the mound. The Brewers are first in the NL Central with a 96-65 record and have right-hander Freddy Peralta getting the ball. First pitch focus — MLB picks for Cincinnati Reds vs. Milwaukee Brewers that cut through the noise.
Reds Looking to End the Year on the Right Foot
The Cincinnati Reds are looking to build off Saturday’s 7-4 road win against the Milwaukee Brewers in their most recent game. The Reds were able to go 10-for-38 with seven walks and 13 strikeouts at the plate as a team as Sal Stewart hit a home run. Cincinnati finished 3-for-12 with runners in scoring position while leaving 12 men on base. Andrew Abbott pitched well enough as he won by going 5.1 innings and allowing three runs.
Right-hander Brady Singer is going to be taking the mound for the Cincinnati Reds in this game and has been stepping up as he is 14-11 with a 3.95 ERA and a 1.23 WHIP in 166.1 innings over 31 starts. He has been able to limit the number of homers as he has given up 18 in his first season with the team. Singer is facing the Brew Crew for the third time this season and is 1-1 in 10.0 innings and allowed eight runs (six earned) on 13 hits with four walks and 11 strikeouts.
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Injury Report for Cincinnati
- Pitcher Nick Lodolo: Groin (Questionable)
- Pitcher Ian Gibaut: Shoulder (OUT)
- Pitcher Wade Miley: Flexor (OUT)
- Pitcher Rhett Lowder: Forearm (OUT)
- Pitcher Carson Spiers: Shoulder (OUT)
- Left fielder Tyler Callihan: Forearm (OUT)
- Pitcher Brandon Williamson: Elbow (OUT)
- Pitcher Julian Aguiar: Elbow (OUT)
Brewers Waiting Until the Playoffs
The Milwaukee Brewers are looking to bounce back from their 7-4 home loss against the Cincinnati Reds on Saturday in the penultimate game of the regular season. The lineup was able to go 7-for-34 with three walks and seven strikeouts on the day as Jackson Chourio hit a homer. The Brew Crew went 2-for-7 with runners in scoring position and stranded seven men on base. Robert Gasser recorded the loss as he pitched 2.2 innings and gave up four runs.
The Brewers are sending righty Freddy Peralta to pitch and he is making his 33rd start of the season. He is 17-6 with a 2.68 ERA and a 1.07 WHIP in 174.2.0 innings so far. He has been able to limit the number of hits allowed as he has a .191 batting average against so far. Peralta faced the Reds once this season in a loss as he gave up three runs on seven hits with three walks and nine strikeouts over six innings on the bump.
Injury Report for Milwaukee
- Pitcher Brandon Woodruff: Lat (OUT)
- Pitcher Jose Quintana: Calf (OUT)
- Pitcher Shelby Miller: Elbow (OUT)
- Pitcher Tylor Megill: Flexor Strain (OUT)
- Pitcher Logan Henderson: Elbow (OUT)
- Pitcher DL Hll: Oblique (OUT)
- Pitcher Jordan Montgomery: Elbow (OUT)
- Center fielder Garrett Mitchell: Oblique (OUT)
- Pitcher Connor Thomas: Elbow (OUT)
Cincinnati Reds vs. Milwaukee Brewers Pick
Spread Pick for Reds vs. Brewers
- Cincinnati Reds ML (5 units)
The Cincinnati Reds seem like they know they are just going through the motions until the NLDS, as they have already clinched home-field advantage throughout the playoffs. In September, there is a slight difference between these pitchers as Brady Singer is 2-2 with a 3.13 ERA and a .207 batting average against in 23.0 innings (four starts) while Freddy Peralta is 1-1 with a 3.43 ERA and a 1.05 WHIP in 21.0 innings (four starts) so far. +All in all, go with the Cincinnati Reds to end this series with a sweep.
Over/Under Pick for Reds vs. Brewers
- Under (4 units)
When looking at the previous seven starts, these pitchers are not giving up runs as Brady Singer is 4-2 with a 2.85 ERA and a 0.98 WHIP in 41.0 innings of work in that span. Freddy Peralta is 3-1 with a 1.89 ERA and a 0.89 WHIP in 38.0 innings. In the previous seven days, these teams have not been hitting too well as the Reds are 20th with a .644 team OPS while averaging 3.0 runs per game, while the Brewers are 29th with just a .534 team OPS while scoring 2.17 runs per game. The under hit in the first two games of the season, so take the under here.
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