Cincinnati Reds vs Milwaukee Brewers Picks and Prediction for Sunday September 13 2026

The Cincinnati Reds visit the Milwaukee Brewers at American Family Field in Milwaukee, Wisconsin, on Sunday, September 13, 2026. First pitch is scheduled for 2:10 PM ET with coverage on MLB.TV. Cincinnati enters at 69-78 overall and 33-40 on the road, while Milwaukee is 92-56 overall and 51-25 at home. The Brewers won the series opener 20-0 and enter Sunday on a four-game winning streak, while the Reds have dropped four straight. At the time of this writing the odds were not released. Be sure to check out our free MLB picks for more MLB predictions throughout the season.

Starting Pitchers

Cincinnati is scheduled to start Chase Burns, who enters at 15-3 with a 2.73 ERA and 1.14 WHIP through 148.1 innings. He has allowed 118 hits and 15 home runs while recording 176 strikeouts against 51 walks. Milwaukee counters with Shane Drohan, who is 7-5 with a 4.09 ERA and 1.31 WHIP across 114.1 innings. He has surrendered 111 hits and 12 home runs while striking out 115 and walking 39. Cincinnati owns the clear starting-pitching advantage based on the supplied numbers, particularly in ERA, WHIP, strikeouts and overall record.

Cincinnati Needs Its Starter to Stop the Slide

Cincinnati enters Sunday at 69-78 overall and 33-40 away from home. The Reds have lost four straight games, including a 20-0 defeat in the series opener. Their other recent losses came by scores of 14-1, 3-2 and 6-3, while their lone victory over the last five was a 12-8 win. Cincinnati has therefore been outscored heavily during the current losing streak, with two of those defeats coming by double digits.

The Reds are batting .229 with 611 runs, 1,119 hits and 196 home runs. They own a .307 on-base percentage and .396 slugging percentage. Their pitching staff carries a 4.84 ERA and 1.44 WHIP while opponents are batting .254. Cincinnati has recorded 1,192 strikeouts against 604 walks and owns a 30-27 record in day games.

Cincinnati's biggest strength is power, as the Reds have hit considerably more home runs than Milwaukee. The problem is that nearly every other major team category favors the Brewers. Cincinnati has the weaker batting average, on-base percentage, ERA, WHIP and opponent batting average. Sunday's scheduled starter gives the Reds a legitimate chance to remain competitive, but they need a major turnaround after allowing 34 runs over their last two games.

Milwaukee Continues to Roll at Home

Milwaukee enters Sunday at 92-56 overall and 51-25 at American Family Field. The Brewers have won four consecutive games, taking their last four by scores of 20-0, 8-6, 4-3 in 10 innings and 4-3. Their only loss over the last five came in a 12-8 decision. Milwaukee's offense exploded in the series opener, but the Brewers have also shown they can win close games.

The Brewers are batting .259 with 762 runs, 1,303 hits and 141 home runs. They own a .341 on-base percentage and .404 slugging percentage. Their pitching staff has been excellent with a 3.53 ERA and 1.18 WHIP while opponents are batting only .221. Milwaukee has recorded 1,414 strikeouts against 477 walks and is 33-21 in day games.

Milwaukee's strength is its balance. The Brewers have the much better batting average, on-base percentage, run production and pitching profile, and their 51-25 home record is another major advantage. Cincinnati has more home runs and the superior scheduled starter, but Milwaukee has been the significantly better overall team and carries the stronger recent form into Sunday.

Cincinnati Reds vs Milwaukee Brewers Picks and Prediction

Pick: Milwaukee Brewers Moneyline

The Milwaukee Brewers Moneyline is the preferred side. Cincinnati has the better scheduled starter, but Milwaukee owns the stronger overall profile by a wide margin. The Brewers are 23 games better in the standings, have won four straight and are 51-25 at home. Cincinnati, meanwhile, has lost four in a row and was beaten 20-0 in the series opener. The starting matchup keeps this from being an automatic blowout call, but Milwaukee's superior offense, bullpen-level team profile and home form make the Brewers the better side.

Pick: Under 8.5

Take the Under if the total is set at 8.5 or higher. The series opener was an extreme scoring outlier, but Sunday's pitching matchup is much different. Cincinnati's scheduled starter enters with a 2.73 ERA and 1.14 WHIP while recording 176 strikeouts, giving the Reds their best chance to suppress Milwaukee's offense. The Brewers' starter has been less effective, but Cincinnati has scored only six runs over its last four games. At 8.5 or higher, the Under is the better target.

Final Picks: Milwaukee Brewers Moneyline and Under 8.5

This preview was completed on Saturday. Starting pitchers, betting lines and other game information are subject to change before the game begins.