Cincinnati Reds vs St. Louis Cardinals Picks and Prediction for Sunday June 7 2026

The Cincinnati Reds and St. Louis Cardinals will meet at Busch Stadium in St. Louis, Missouri, on Sunday, June 7, 2026, at 2:15 PM ET. The game will be televised on MLB.TV. At the time of this writing the odds were not released. Be sure to check out our free MLB picks.

Starting Pitchers

The Reds are expected to start Rhett Lowder, who is 3-3 with a 5.40 ERA and a 1.41 WHIP across 38.1 innings. He has allowed 36 hits, struck out 27 batters, walked 18, and surrendered 2 home runs. The Cardinals are expected to counter with Michael McGreevy, who is 3-5 with a 2.98 ERA and a 1.10 WHIP over 66.1 innings. He has allowed 56 hits, recorded 44 strikeouts, issued 17 walks, and given up 8 home runs.

Cincinnati Looking for a Better Finish to the Series

The Reds enter this matchup with a 31-31 overall record and a 15-15 mark on the road. Cincinnati recently lost to St. Louis 10-3, lost to Kansas City 5-2, defeated Kansas City 4-3 in 10 innings, lost to Kansas City 9-2, and defeated Atlanta 6-4. The Reds have won two of their last five games and are coming off a difficult loss in the most recent meeting against the Cardinals.

Cincinnati is batting .229 with 267 runs, 477 hits, and 77 home runs. The Reds own a .312 on-base percentage and a .394 slugging percentage. Their pitching staff has posted a 4.81 ERA and a 1.47 WHIP while allowing opponents to hit .250. Cincinnati has also drawn 288 walks and recorded 486 strikeouts.

The biggest strength for Cincinnati is its power production. The Reds have hit 77 home runs, which is more than St. Louis has produced this season. However, the pitching numbers have been a challenge, as Cincinnati enters with the higher ERA and WHIP in this matchup.

St. Louis Bringing Momentum into Sunday

The Cardinals come into the game with a 33-28 overall record and a 17-16 record at home. St. Louis recently defeated Cincinnati 10-3, beat Texas 5-3, lost to Texas 7-4, lost to Texas 2-1, and defeated Chicago 5-1. The Cardinals have won three of their last five games and will try to continue that success after a convincing victory over the Reds.

St. Louis is batting .241 with 267 runs, 494 hits, and 66 home runs. The Cardinals have a .320 on-base percentage and a .385 slugging percentage. On the mound, they own a 4.13 ERA and a 1.36 WHIP while allowing opponents to hit .254. The pitching staff has issued 216 walks and recorded 472 strikeouts.

The Cardinals' key advantage is run prevention. St. Louis has a significantly lower ERA and WHIP than Cincinnati, and that difference has helped the Cardinals maintain a better overall record. The recent 10-3 victory over the Reds further highlights that advantage.

Cincinnati Reds vs St. Louis Cardinals Picks and Prediction

Cincinnati Reds vs St. Louis Cardinals Pick

• Pick: St. Louis Cardinals Moneyline

The Cardinals are the preferred side based on the information provided. St. Louis owns the better overall record, the stronger matchup predictor percentage, and the more effective pitching staff. The Cardinals also won the most recent meeting 10-3 and enter this contest with a lower ERA and WHIP than Cincinnati. Those factors make St. Louis the stronger play.

Cincinnati Reds vs St. Louis Cardinals Total Pick

Pick: Over

• Take the over if the total is set at 8.5.

I lean toward the over because Cincinnati's pitching staff carries a 4.81 ERA and a 1.47 WHIP, while the most recent meeting between these teams produced 13 total runs. The Reds have also been involved in games with nine, 13, and 10 total runs during their last five contests. That recent scoring environment points toward the over.

Final Score Prediction: St. Louis Cardinals 6 – Cincinnati Reds 4

This prediction was written before the completion of game play on Saturday.