Cleveland Guardians vs Chicago White Sox Picks and Prediction for Wednesday June 24 2026
Use Code SSWC The Cleveland Guardians and Chicago White Sox continue their series on Wednesday, June 24, 2026, at Rate Field in Chicago, Illinois. First pitch is scheduled for 2:10 PM ET, with coverage available on MLB.TV. At the time of this writing the odds were not released. Be sure to check out our free MLB picks.
Starting Pitchers Take Center Stage
Cleveland is scheduled to send Tanner Bibee to the mound. He enters this matchup with a 2-8 record, a 4.03 ERA, and a 1.18 WHIP across 89.1 innings. He has allowed 77 hits while striking out 78 batters, walking 28, and surrendering 16 home runs. Chicago is expected to counter with Erick Fedde, who comes into the game with a 2-6 record, a 4.46 ERA, and a 1.39 WHIP in 70.2 innings. He has given up 71 hits, struck out 48 batters, issued 27 walks, and allowed 14 home runs.
Cleveland Looking to Bounce Back
The Guardians enter this contest with a 41-38 overall record and a 22-21 record on the road. Cleveland has split its last five games, going 2-3 during that stretch. The Guardians recently lost to Chicago and Houston twice but picked up victories over Houston and Milwaukee.
Offensively, Cleveland owns a .228 team batting average with 315 runs scored, 591 hits, and 74 home runs. The club has produced a .313 on-base percentage and a .369 slugging percentage. On the mound, the Guardians have posted a 3.82 ERA with a 1.26 WHIP. They have recorded 723 strikeouts while allowing opponents to hit .237 against them.
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The biggest strength for Cleveland has been its pitching staff. The Guardians hold the lower team ERA in this matchup and have generated considerably more strikeouts than Chicago. Even though the offense has not produced at the same level as some contenders, the pitching numbers have helped keep Cleveland above .500 throughout the season.
Chicago Hoping to Build on the Series Opener
Chicago comes into this matchup with a 40-37 overall record and an impressive 25-12 home record. The White Sox are 2-3 over their last five games. They recently defeated Cleveland and New York but suffered three consecutive losses to Detroit before opening this series with a win.
The White Sox are batting .238 as a team with 359 runs, 608 hits, and 107 home runs. They have produced a .319 on-base percentage and a .410 slugging percentage. Chicago's pitching staff has compiled a 4.42 ERA and a 1.34 WHIP while recording 634 strikeouts. Opponents are hitting .242 against the White Sox this season.
The strength of Chicago's club has clearly been its power production. The White Sox have hit 107 home runs, significantly more than Cleveland's 74. They have also scored more runs and posted a higher slugging percentage. Those offensive advantages have helped Chicago build one of the strongest home records in the league.
Cleveland Guardians vs Chicago White Sox Picks and Prediction
Cleveland Guardians vs Chicago White Sox Pick
- Pick: Cleveland Guardians Moneyline
This matchup appears extremely competitive, which is reflected by the matchup predictor showing only a slight edge for Cleveland. The Guardians have the better overall record, the stronger pitching numbers, and the lower ERA. Their projected starter also owns the better ERA and WHIP entering this contest. Chicago's home record is excellent, but Cleveland's pitching advantages give the visitors a slight edge.
Cleveland Guardians vs Chicago White Sox Total Pick
- Take the under if the total is set at 8.
I would lean toward the under if the number is set at 8. Cleveland's pitching staff has been one of the better units in this matchup, posting a 3.82 ERA and allowing opponents to hit just .237. While Chicago has shown more power throughout the season, both starting pitchers have ERAs near the low-to-mid fours, which could keep scoring from getting out of control. With two fairly evenly matched clubs, I expect a competitive game that stays around the number.
Final Score Prediction: Cleveland Guardians 4 – Chicago White Sox 3
This prediction was written before the completion of game play on Tuesday.
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