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Colorado Rockies vs. Los Angeles Dodgers Prediction and Picks – September 10, 2025

By: Andy Hammel Updated 10/31/2025, 03:51 PM ET
Giants vs Dodgers Prediction

The Rockies and Dodgers will play the third game of their series in Los Angeles this Wednesday, and we'll preview the lines and odds in our Colorado Rockies vs. Los Angeles Dodgers prediction. The Dodgers are up 2-0 in the series after winning 7-2 on Tuesday night, becoming the latest team to dominate a series against the moribund 2025 iteration of the Rockies. Game 3 will start at 10:10 PM ET on Wednesday, September 10.

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Can Rockies Win a Game This Series?

The Rockies rank firmly at the bottom of the 2025 MLB standings – they're 40-105 overall, 4-16 in their last 20 outings, and weeks past being eliminated from playoff contention. As far as the long-term health of the franchise is concerned, there's little left at stake down the stretch of the regular season. The Rockies, in September, are playing for pride and the extension of their professional careers. Can they do enough against the Dodgers on Wednesday to keep things interesting, if not prevent a sweep?

Colorado ranks 29th in runs (543), 22nd in batting average (.241), and 27th in OPS (.690) among MLB teams heading into Wednesday. Their pitching ranks 30th in ERA (6.00), opposing batting average (.298), and WHIP (1.60). Additionally, the Rockies have logged only 967 strikeouts–103 behind the 29th-place Cardinals, putting them easily at the bottom in another key pitching metric.

Kyle Freeland will start for the Rockies on Wednesday. He leads the team in innings pitched (139.1) and strikeouts (107), with a 5.10 ERA and a 1.45 WHIP. He's 4-14 this season, but logged a win in the Rockies' 3-0 victory over the Padres on September 5.

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Will Dodgers Stay Atop NL West?

The Dodgers are cruising to a berth in the 2025 playoffs at 81-64 overall, but they're only two spots ahead of the Padres (79-66) and seven spots ahead of the Giants (74-71) for the division lead. With seven games left against the Giants on their regular-season schedule, the Dodgers still have plenty of room to lose ground in the race if they aren't strong down the stretch. Can they stay on top this Wednesday against the most beatable team on their 2025 schedule?

Los Angeles ranks third among MLB teams in runs (722), 9th in batting average (.251), and third in OPS (.763). Their pitching is more toward the middle of the pack, ranking 18th in ERA (4.08), 9th in opposing batting average (.239), and 15th in WHIP (1.28).

Blake Snell will start for the Dodgers on Wednesday. He's 3-4 this season with a 3.19 ERA and 1.49 WHIP, but he's been credited with losses in each of his last three starts: at San Diego (1-2), against Arizona (0-3), and at Pittsburgh (3-5). Snell missed a significant part of the season with left shoulder inflammation–he made only two starts between March and April, before plunging back into the lineup at the start of August.

Colorado Rockies vs. Los Angeles Dodgers Pick

Spread Pick for Rockies vs. Dodgers

  • Los Angeles Dodgers -1.5 (-160)

The Rockies have been dismal in 2025, and they're entering Game 3 of a series against the Dodgers in which they've already lost 1-3 and 2-7. The last time Colorado didn't win a series they played in was against the Dodgers–a series in August, at Colorado, that the teams split 2-2. Their 4-16 record in their last 20 games starts and ends with the Rockies playing the Dodgers. I'd take the Dodgers to extend that success before I'd take the Rockies to do anything about it.

Over/Under Pick for Rockies vs. Dodgers

  • Under 8.5 (-115)

The Team Total Under is 6-2-2 in the Dodgers' last ten games. The Rockies have three wins since their home series against the Dodgers in August; they've posted three zero-run offensive games over the same stretch. If the Dodgers' offense dictates this game, as they should, then I wouldn't bet on a high point total at the end.

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