Colorado Rockies vs. Seattle Mariners Picks and Prediction for Tuesday, September 23, 2025
The Colorado Rockies (43-113, 69-83-4 O/U) will be taking on the Seattle Mariners (87-69, 85-66-5 O/U) on Tuesday night in the opening game of a three-game interleague series for our Rockies vs. Mariners prediction. Both teams are off on Monday, so they are rested for this matchup. Rookie right-hander McCade Brown (0-4, 9.17 ERA) is going to be pitching in this game for the Rockies, while the Mariners are sending righty Bryce Miller (4-5, 5.58 ERA) to the hill. From splits to bullpens, MLB predictions for the Colorado Rockies vs. the Seattle Mariners highlight the edge.
Rockies Looking to Play Spoiler
The Colorado Rockies are looking to end the season well as they are fifth in the NL West with a 43-113 record up to this point. The offense is playing at a terrible level as they are 27th in the sport with a .239/.295/.389 team slash line while scoring 3.74 runs per game.
The Colorado Rockies are coming off a 3-1 home win over the Los Angeles Angels on Sunday, and it helped as Blaine Crim hit a home run. Kyle Freeland picked up a win as he threw six shutout innings.
Center fielder Brenton Doyle (.650 OPS, 30 walks) has been struggling and could use a resurgence in the last week of the season to improve his numbers a bit. Rookie righty McCade Brown (0-4, 9.17 ERA) is going to be on the mound and is coming off a no-decision against the Miami Marlins, where he gave up three runs on four hits with four walks and one strikeout.
Injury Report for Colorado
- Pitcher Chase Dollander: Knee (OUT)
- Pitcher Luis Peralta: Hip (OUT)
- Shortstop Warming Bernabel: Concussion (OUT)
- Pitcher Dugan Darnell: Hip (OUT)
- Second baseman Thairo Estrada: Hamstring (OUT)
- Pitcher Seth Halvorsen: Elbow (OUT)
- Pitcher Zach Agnos: Hand (OUT)
- Designated hitter Kris Bryant: Lumbar (OUT)
- Pitcher Jeff Criswell: Elbow (OUT)
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Mariners Trying to Lock Down AL West Crown
The Seattle Mariners are looking to continue their hot stretch to end the season as they are currently leading the AL West with an 87-69 record up to this point. The offense is performing well as they are 11th in MLB with a .244/.320/.420 team slash line while averaging 4.75 runs per game.
The Seattle Mariners were able to secure a 7-3 road win over the Houston Astros on Sunday, and it helps as J.P. Crawford and Cal Raleigh each hit home runs. Logan Gilbert pitched well as he gave up one run in six innings in the victory.
Center fielder Julio Rodriguez (31 HR, 28 SB) has been putting up an outstanding season and should continue to hit as the season winds down. Right-hander Bryce Miller (4-5, 5.58 ERA) will get the start here and is coming off a no-decision against the Kansas City Royals, where he allowed three runs on eight hits with two walks and four strikeouts in 5.0 innings of work.
Injury Report for Seattle
- Pitcher Bryan Woo: Pectoral (Questionable)
- Pitcher Jackson Kowar: Shoulder (OUT)
- Pitcher Trent Thornton: Achilles (OUT)
- Pitcher Logan Evans: Elbow (OUT)
- Pitcher Gregory Santos: Knee (OUT)
- Second baseman Ryan Bliss: Biceps (OUT)
Colorado Rockies vs. Seattle Mariners Pick
Spread Pick for Rockies vs. Mariners
- Seattle Mariners ML (5 units)
The Seattle Mariners have something to play for here, while the Colorado Rockies are just waiting for the season to be over. The road/home splits show a significant difference offensively as the Rockies are last in MLB with a .593 road OPS while the Mariners are 23rd with a .698 team OPS at home so far. These bullpens have a massive difference as Colorado is 29th in the bigs with a 5.27 reliever ERA while the Mariners is 11th with a 3.73 bullpen ERA. The Mariners are 7-3 in their last 10 games against the Rockies, so go with the Seattle Mariners to record the victory at home.
Over/Under Pick for Rockies vs. Mariners
- Over (4 units)
When diving into the road/home splits this season, both pitchers are getting rocked as McCade Brown is 0-2 with a 6.75 ERA and a 1.88 WHIP in 8.0 innings (two road starts) so far while Bryce Miller is 2-2 with a 5.60 ERA and a .259 batting average against in 35.1 innings (seven home starts) so far. Over the last seven days, these teams are hitting at a good level as Seattle is fourth with a .852 team OPS while Colorado is 15th with a .706 team OPS in that span. All in all, take the over as the better play for this game.
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