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Detroit Tigers vs New York Yankees Picks and Prediction for Wednesday, September 10, 2025

By: Patty Reyes Published 09/10/2025, 10:23 AM ET
Detroit Tigers vs New York Yankees Picks and Prediction for Wednesday, September 10, 2025

The Detroit Tigers (82-62, 75-63-6 O/U) will be taking on the New York Yankees (80-63, 68-69-6 O/U) on Wednesday evening in the middle game of a three-game American League series for our Tigers vs. Yankees prediction. This article is being written ahead of Tuesday’s game. Right-hander Jack Flaherty (7-13, 4.85 ERA) is going to be pitching in this game for the Tigers while the Yankees are sending lefty Carlos Rodon (16-7, 3.12 ERA) to the hill. Cover the diamond — MLB picks for Detroit Tigers vs New York Yankees you can scan fast.

Tigers Looking for Top Seed in AL Playoffs

The Detroit Tigers are doing a great job as they are first in the AL Central with an 82-62 record up to this point. The Tigers are hitting at a solid level as they are tied with the Milwaukee Brewers for 10th in the bigs with a .740 team OPS while averaging 4.83 runs per game.

The Detroit Tigers are coming off a 6-4 home loss against the Detroit Tigers on Sunday as they were hitless in seven at-bats with runners in scoring position. Charlie Morton struggled in a no-decision as he pitched three innings and allowed three runs.

 

Third baseman Zach McKinstry (.789 OPS, 19 SB) has been a solid hitter who has stepped up throughout the course of the season. Right-hander Jack Flaherty (7-13, 4.85 ERA) will be taking the mound and did not factor into the decision against the Chicago White Sox as he pitched 4.1 innings and allowed four runs on six hits with one hit by pitch, two walks, and two strikeouts.

Injury Report for Detroit

  • Pitcher Kyle Finnegan: Abductor (OUT)
  • Center fielder Matt Vierling: Oblique (OUT)
  • Pitcher Paul Sewald: Shoulder (OUT)
  • Pitcher Reese Olson: Shoulder (OUT)
  • Pitcher Sean Guenther: Hip (OUT)
  • Pitcher Jackson Jobe: Flexor (OUT)
  • Pitcher Jason Foley: Shoulder (OUT)
  • Pitcher Alex Cobb: Hip (OUT)
  • Pitcher Ty Madden: Shoulder (OUT)
  • Pitcher Jose Urquidy: Elbow (OUT)

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Yankees Fighting for AL East Crown

The New York Yankees are looking to continue stepping up as they are second in the AL East with an 80-63 record up to this point. The offense is hitting at an incredible level as they are first in baseball with a .249/.330/.454 team slash line while averaging 5.45 runs per game.

The New York Yankees are coming off Sunday’s 4-3 home win over the Toronto Blue Jays as Ben Rice hit a home run while Aaron Judge and Jazz Chisholm Jr each stole a base. Max Fried stepped up as he recorded the win by throwing seven innings and giving up three runs.

Shortstop Anthony Volpe (19 HR, 16 SB) needs to find some offensive consistency to make this lineup even more dominant. Left-hander Carlos Rodon (16-7, 3.12 ERA) is going to be on the mound and is coming off a win over the Houston Astros, where he threw six innings and gave up two runs (one earned) on three hits with a pair of walks and three strikeouts.

Injury Report for New York

  • Pitcher Brent Headrick: Forearm (OUT)
  • Pitcher Jonathan Loaisiga: Back (OUT)
  • Pitcher Clarke Schmidt: Forearm (OUT)
  • Third baseman Oswaldo Cabrera: Ankle (OUT)
  • Pitcher Jake Cousins: Elbow (OUT)
  • Pitcher Gerrit Cole: Elbow (OUT)

Detroit Tigers vs. New York Yankees Pick

Spread Pick for Detroit Tigers vs. New York Yankees

  • New York Yankees ML (5 units)

When diving into the previous seven starts for these pitchers, there is a massive difference in the outcome. Jack Flaherty is 1-3 with a 5.84 ERA and a 1.38 WHIP in 37.0 innings while Carlos Rodon is 5-0 with a 2.90 ERA and a 1.17 WHIP in 40.1 innings during that stretch. These teams are showing a gap in the ability to hit home runs as the Tigers are ninth in baseball with 26.89 at-bats per home run hit while the Yankees are best in the sport with 19.92 at-bats between homers thus far. All in all, go with the New York Yankees to secure the win.

Over/Under Pick for Detroit Tigers vs. New York Yankees

  • Over (4 units)

These teams have hit well with runners in scoring position this year as the Tigers are fourth in MLB with a .792 team OPS in those opportunities while the Yankees are ninth with a .770 team OPS with runners in scoring position thus far. Both teams avoid hitting into double plays throughout the season as Detroit is third in the majors with 81 double plays hit into while New York is 11th with 89 double plays hit. All in all, go with the over as the better bet.

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