Free MLB Picks Today – MLB Best Bets For Friday, September 12 2025
Last night’s 1-2 slip is already in the rearview as we turn the page to a brand-new MLB slate. Today’s board is loaded with opportunity, and we’ve zeroed in on three spots that bring serious betting value. With sharp pitching insights, offensive trends, and key matchup angles, these best bets are designed to put us right back in the win column. It’s time to shake off yesterday and attack today’s card with confidence.
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Pittsburgh Pirates vs Washington Nationals
Pittsburgh is a solid value play tonight over Washington, with Mitch Keller giving the Pirates a clear edge on the mound. Keller enters with a 4.16 ERA and 162.1 innings of work this season, and while his win-loss record is underwhelming, he’s backed by a bullpen that ranks top-10 in WHIP and opponent batting average. Washington counters with Brad Lord (5–8, 4.20 ERA), who’s allowed a .254 opponent average and has struggled to generate swing-and-miss against contact-heavy lineups. The Nationals have dropped four of their last six and were shut out in their most recent outing, while Pittsburgh—despite a six-game skid—has shown flashes of offensive life behind Bryan Reynolds and Oneil Cruz. With Keller capable of working deep and Washington’s lineup lacking consistency, the Pirates have the pitching edge and enough run support to snap their losing streak and take the opener at Nationals Park.
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| # | Handicapper | Profit |
|---|---|---|
| 1 |  Rob Vincilleti | +1,502.00 |
| 2 |  Pro Sports Picks | +1,421.00 |
| 3 |  Brick Haus Sports | +634.00 |
| 4 |  David Delano | +492.00 |
| 5 |  Michael Briggs | +355.00 |
Chicago White Sox vs Cleveland Guardians
Cleveland is a strong favorite to take care of business tonight at Progressive Field, with Tanner Bibee on the mound and playoff positioning still in play. The Guardians have won 60% of games as favorites this season and are 6–1 when favored at -173 or higher. Bibee enters with a 4.69 ERA and has gone at least five innings in six straight starts, while Chicago counters with Martín Pérez, who’s just 1–4 on the year and owns a 7.39 career ERA against Cleveland. The White Sox rank bottom-five in MLB in runs scored, slugging, and OBP, and their bullpen has blown nearly half of its save opportunities. With Cleveland’s superior pitching depth, home-field edge, and urgency in the standings, the Guardians are well-positioned to cover the moneyline and extend Chicago’s skid.
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Los Angeles Angels vs Seattle Mariners (Total)
Tonight’s Angels-Mariners matchup at T-Mobile Park sets up well for the Over 7.5, with power bats on both sides and starting pitchers who’ve shown vulnerability against these lineups. Seattle’s Luis Castillo (3.85 ERA) has allowed a .258 opponent batting average this season and gave up four earned runs in five innings the last time he faced the Angels. Los Angeles counters with Yusei Kikuchi (4.18 ERA), who’s just 1–8 on the road and faces a Mariners squad that ranks third in MLB with 213 home runs. Both teams have hit the Over in more than half their games this season, and with sluggers like Cal Raleigh, Julio Rodríguez, Jo Adell, and Zach Neto all in the lineup, there’s enough firepower to push this total past the number in a hitter-friendly Friday night spot.
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The Picks Are In:
- Pittsburgh -107 over Washington
- Cleveland -145 over Chicago
- LA Angels/ Mariners Over 7.5
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