Houston Astros vs Atlanta Braves Picks and Prediction for Friday, September 12, 2025
In the opening game of a three-game interleague series, the Houston Astros are taking on the Atlanta Braves inside Truist Park on Friday evening in our Astros vs. Braves prediction. The Astros are coming off a 6-0 road loss on Thursday against the Toronto Blue Jays while the Braves are off Thursday. The Astros are first in the AL West with a 79-68 record and are sending rookie right-hander AJ Blubaugh to the mound. The Braves are fourth in the NL East with a 65-81 record and have rookie right-hander Hurston Waldrep getting the ball. From splits to bullpens, MLB predictions for the Houston Astros vs the Atlanta Braves highlight the edge.
Astros Looking to Recover
The Houston Astros are looking to recover after their 6-0 road loss against the Toronto Blue Jays on Thursday. The lineup was limited to just 2-for-29 with one walk and nine strikeouts on the day. Houston went 0-for-3 with runners in scoring position and stranded all three men on base. Cristian Javier recorded a loss in this start as he allowed four runs in six innings of work.
The Astros are sending rookie righty AJ Blubaugh to pitch and he is doing well as in seven games (one start), he is 2-1 in 21.0 innings with a 2.57 ERA and a 0.90 WHIP. He has dominated as he has a .171 batting average against so far this year. Blubaugh is facing the Braves for the first time in his young career, so this will be a good test.
Injury Report for Houston
- Pitcher Luis Garcia: Elbow (OUT)
- Pitcher Kaleb Ort: Elbow (OUT)
- Pitcher Spencer Arrighetti: Elbow (OUT)
- Pitcher John Rooney: Concussion/Nasal (OUT)
- Pitcher Bennett Sousa: Elbow (OUT)
- Pitcher Brandon Walter: Elbow (OUT)
- Pitcher Josh Hader: Shoulder (OUT)
- Third baseman Isaac Paredes: Hamstring (OUT)
- Second baseman Brendan Rodgers: Oblique (OUT)
- Right fielder Zach Dezenzo: Hand (OUT)
- Right fielder Pedro Leon: Knee (OUT)
- Pitcher Ronel Blanco: Elbow (OUT)
- Pitcher Hayden Wesneski: Elbow (OUT)
Sign Up for StatSalt News Alerts, Get Free Picks and Discounts
Subscribe Now
Second sub-title
The Atlanta Braves are looking to recover after Wednesday’s 3-2 home loss on Wednesday against the Chicago Cubs in their most recent game. The Braves were able to go 7-for-31 with a pair of walks and seven strikeouts at the plate. Atlanta finished 2-for-7 with runners in scoring position while leaving five men on base. Chris Sale did a good job despite recording the loss as he allowed three runs in five innings.
Rookie right-hander Hurston Waldrep is going to be taking the mound for the Braves in this game and has been pitching well as he is 4-0 with a 2.85 ERA and a 1.06 WHIP in 40.2 innings over seven games (six starts). He has been doing an incredible job in terms of limiting the amount of homers hit, as he has allowed two this year. Waldrep has not pitched against the Astros in his young career.
Injury Report for Atlanta
- Catcher Sean Murphy: Hip (OUT)
- Third baseman Austin Riley: Abdominal (OUT)
- Pitcher Aaron Bummer: Shoulder (OUT)
- Pitcher Grant Holmes: Elbow (OUT)
- Pitcher Spencer Schwellenbach: Elbow (OUT)
- Pitcher AJ Smith-Shawver: Calf/Elbow (OUT)
- Pitcher Reynaldo Lopez: Shoulder (OUT)
- Pitcher Joe Jimenez: Knee (OUT)
Houston Astros vs. Atlanta Braves Pick
Spread Pick for Houston Astros vs. Atlanta Braves
- Houston Astros ML (4 units)
AJ Blubaugh and Hurston Waldrep are very similar with their production this season, so there is not too much of a difference between them. Since the All-Star break, the Astros are 20th with a 4.29 team ERA, while the Braves are 27th with a 5.43 team ERA. In September, there has been a difference in how these offenses are performing as Houston is averaging 4.3 runs per game while Atlanta is scoring 3.22 runs per game in the calendar month. All in all, go with the Houston Astros to secure the victory.
| # | Handicapper | Profit |
|---|---|---|
| 1 |  Rob Vincilleti | +1,502.00 |
| 2 |  Pro Sports Picks | +1,421.00 |
| 3 |  Brick Haus Sports | +634.00 |
| 4 |  David Delano | +492.00 |
| 5 |  Michael Briggs | +355.00 |
Over/Under Pick for Houston Astros vs. Atlanta Braves
- Under (5 units)
These offenses over the last few weeks show some lack of attention as Houston is averaging 3.57 runs in their last 14 game,s while Atlanta is scoring 3.0 runs in their previous 13 games played. The bullpens have been showing a good ability to step up as a whole with the Astros ranking ninth in MLB with a 3.73 reliever ERA while the Braves are 20th with a 4.31 bullpen ERA right now. The under hit in the last four games against one another, so take the under here.
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Bet $5 & Get $150
